Results 41 to 50 of about 123,273 (258)

Preventive maintenance scheduling: a simulation-optimization approach

open access: yesProduction and Manufacturing Research: An Open Access Journal, 2021
This paper presents a framework for preventive maintenance (PM) scheduling in the semiconductor industry. We propose an approach for finding PM’s start time within a PM window to minimize production losses due to maintenance activities. In this study, we
Agus Darmawan, D. Daniel Sheu
doaj   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

DETERMINATION OF THE OPTIMAL VEHICLE MAINTENANCE STRATEGY AS ONE OF THE CONDITIONS OF IMPROVING THE SAFETY OF TRAFFIC [PDF]

open access: yesProceedings on Engineering Sciences, 2019
Two types of preventive maintenance are mostly used. First is preventive maintenance based on reliability information (on empirically defined distribution of possibility of work time until breakdown). By application of this type of preventive maintenance,
Vojislav KRSTIĆ, Boris ANTIĆ
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Investigation of Maintenance Methods

open access: yesDüzce University Faculty of Forestry Journal of Forestry, 2008
Cleaning, lubrication, overhaul, calibration and experiments conducted bymaintenance personnel make up maintenance tasks. It is essential that an activemaintenance planning be implemented in order that production functions could carry onuninterruptedly ...
Derya Sevim Korkut   +2 more
doaj  

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Study of Using Weighting Property Index for Selecting the Best Maintenance Management System (MMS) at Power Plants

open access: yesDiyala Journal of Engineering Sciences, 2018
To make Power Plants (PPs) economical, the maintenance functions should be optimized by carefully selecting and planning the Maintenance Management System (MMS) that will address the maintenance needs of the plant at the least cost.
Lamyaa M. Dawood   +2 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

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