Results 51 to 60 of about 123,273 (258)
Maintenance Optimization for Repairable Deteriorating Systems under Imperfect Preventive Maintenance
This study deals with the preventive maintenance optimization problem based on a reliability threshold. The conditional reliability threshold is used instead of the system reliability threshold.
Juhyun Lee, Byunghoon Kim, Suneung Ahn
doaj +1 more source
Preventive maintenance scheduling with integer programming and constraint programming [PDF]
Preventive maintenance scheduling is to perform a series of tasks that prevents or minimizes production breakdowns and improves the reliability. Mathematical models have been developed to solve the preventive maintenance scheduling problem.
Majid Esmaelian, Hajar Bakran
doaj +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Mofularity design has been applied in many European countries, especially in industrial assembling and manufacturing. Modularity design cause manufacture process and assembly process easier and cheaper.
Julianingsih Julianingsih +1 more
doaj
Considering that the entire electric multiple unit (EMU) needs to be withdrawn from service for carrying out preventive maintenance (PM) of the critical equipment, leading to an increase to downtime loss, the concept of replacement repair is proposed in ...
XIONG Lü, LIU Zhilong
doaj
The Role of Managerial Commitment and TPM Implementation Strategies in Productivity Benefits
The present research proposes a structural equation model to integrate four latent variables: managerial commitment, preventive maintenance, total productive maintenance, and productivity benefits.
José Roberto Díaz-Reza +5 more
doaj +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Research of Preventive Maintenance Task Optimization of Military Aircraft Based on S4000P
Preventive maintenance is the main measure to restore and maintain the safety and reliability of the aircraft, and its optimization as a common concern is concerned by both aircraft manufacturers and users.
NAN Yanfei, JIANG Qingxi, LIN Cong
doaj +1 more source
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source

