Results 71 to 80 of about 431,604 (298)

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Maintenance management and servises (case study: PERKESO building's in penisular of Malaysia) [PDF]

, 2006
Maintenance Management and Services is a combination of several actions in which to retain or restore an item to perform its required action. PERTUBUHAN KESELAMATAN SOSIAL (PERKESO) as one of the semi government sector in Malaysia that has many assets ...
Hashim, Ahmad Riza
core  

A review of multi-component maintenance models with economic dependence [PDF]

, 1997
In this paper we review the literature on multi-component maintenance models with economic dependence. The emphasis is on papers that appeared after 1991, but there is an overlap with Section 2 of the most recent review paper by Cho and Parlar (1991). We
A Federgruen, A Haurie, BD Sivazlian, BL Kralj, D Assaf, D Sculli, DI Cho, DR Suie, DW Jorgenson, EA Silver, FA Duyn Schouten Van der, FA Duyn Schouten Van der, Frank A. van der Duyn Schouten, G Dijkhuizen Van, IB Gertsbakh, IB Gertsbakh, J Jansen, JJ McCall, JM Worm, JP Stinson, JS Dagpunar, K Okumoto, K Tatsuno, LC Thomas, M Berg, M Berg, M Berg, M Hariga, M Hariga, M Kaspi, M Ohashi, MA Hariga, MJG Eijs Van, MJG Eijs Van, MR Garey, N Fard, P Ritchken, PL Jackson, R Dekker, R Dekker, R Dekker, R Dekker, R Dekker, R Dekker, R Dekker, R Radner, Ralph E. Wildeman, RC Vergin, Rommert Dekker, S Epstein, S Wael Vos de, S Özekici, SG Vanneste, SH Sheu, SK Goyal, SK Goyal, SK Goyal, SK Goyal, SO Duffuaa, T Aven, TW Archibald, TY Liang, W Bäckert, WL Maxwell   +63 more
core   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Research of Preventive Maintenance Task Optimization of Military Aircraft Based on S4000P

Hangkong gongcheng jinzhan, 2020
Preventive maintenance is the main measure to restore and maintain the safety and reliability of the aircraft, and its optimization as a common concern is concerned by both aircraft manufacturers and users.
NAN Yanfei, JIANG Qingxi, LIN Cong
doaj   +1 more source

The Importance of Preventive and Corrective Maintenance in Works [PDF]

, 2018
The present study addresses the problems brought by the lack of preventive and corrective maintenance. The purpose of this work is to focus on the importance of preventive and corrective maintenance, for the prevention and conservation of engineering ...
Balduino, Â. R. (Ângelo), Costa, A. L. (André)   +1 more
core   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Preventive maintenance strategy of electric multiple unit critical equipment based on replacement repair

机车电传动, 2022
Considering that the entire electric multiple unit (EMU) needs to be withdrawn from service for carrying out preventive maintenance (PM) of the critical equipment, leading to an increase to downtime loss, the concept of replacement repair is proposed in ...
XIONG Lü, LIU Zhilong
doaj  

A model based on cost minimization and reliability enhancement to solve the power plant preventive maintenance scheduling problem [PDF]

, 2015
1. Introduction and problem description The Power Plant Preventive Maintenance Scheduling Problem (PPPMSP) requires determining the period for which generating units of an electric power system should be taken offline for planned preventive ...
Perez-Canto, Salvador
core  

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source