Results 141 to 150 of about 4,517,719 (281)

BOPPPS-driven learning plan guidance in preventive medicine laboratory education: Implementation strategy and multidimensional outcomes. [PDF]

BMC Med Educ
Mi W, Lv Z, Song Y, Su M, Meng Q, Xiao L, Zhang B, Kong J, Liu S.   +8 more
europepmc   +1 more source

The multifaceted roles of lysosomes in cancer

Molecular Oncology, EarlyView.
Lysosomes support cancer cell adaptation by integrating macromolecule degradation and nutrient recycling with nutrient sensing, inter‐organelle communication and immune regulation. These interconnected functions can promote tumour growth, stress tolerance and therapy resistance, while also creating context‐dependent vulnerabilities that may be ...
Jia Li, Kevin M. Ryan
wiley   +1 more source

Exploring diverse applications of team-based care in preventive medicine: a scoping review. [PDF]

BMC Prim Care
Nguyen V, S Kumar S, Reyes S, Zhao J, Ng CJ.   +4 more
europepmc   +1 more source

USP7 inhibits FOXO1 activity in chronic lymphocytic leukaemia cells enhancing cell survival

Molecular Oncology, EarlyView.
CLL cells rely on BCR‐mediated signalling for survival and proliferation in part through suppression of FOXO1. FOXO1 activity is regulated by a plethora of post‐translational modifications including phosphorylation and ubiquitination. We demonstrated that dual inhibition of BCR signalling and the deubiquitinase USP7 activates FOXO1, modulating its ...
Hassan N.B. Almuhanna, Jodie Hay, Michael W. Moles, Lucy Clarke, Jennifer Cassels, Alison Sefcick, Alison M. McCaig, Heather G. Jørgensen, Alison M. Michie   +8 more
wiley   +1 more source

Development of an Integrated 6-Year Preventive Medicine Curriculum for Medical Students in Korea: An Expert-informed Deliberative Curriculum Development Study. [PDF]

J Prev Med Public Health
Ahn J, Kang YS, Lee K, Park JH, Ryu SY, Ha M, Choi YJ, Oh J, Lee SH.   +8 more
europepmc   +1 more source

Preventive Medicine on the Farm [PDF]

Nature, 1953
openaire   +2 more sources

The impact of leukocyte‐associated RNA retention on platelet RNA‐based cancer detection

Molecular Oncology, EarlyView.
Platelets carry RNA signals that may help detect cancer, but platelet samples can also retain RNA from white blood cells. We found that this retained white blood cell signal did not significantly affect machine learning cancer classification, suggesting that the cancer‐related RNA signal in platelets is largely independent of leukocyte‐associated RNA ...
Michał Sieczczyński, Krzysztof Pastuszak, Anna Samelak‐Czajka, Zuzanna Cemka, Paulina Jackowiak, Tomasz Stefaniak, Sylwia Łapińska‐Szumczyk, Jacek Jassem, Anna J. Żaczek, Matthew T. Rondina, Myron G. Best, Sjors G. J. G. In 't Veld, Anna Supernat   +12 more
wiley   +1 more source

Society for Veterinary Epidemiology and Preventive Medicine : Proceedings of a meeting held at the University of Bristol on the 24th, 25th and 26th of March 1999

, 1999
Society for Veterinary Epidemiology and Preventive Medicine
core  

The Intersection of Psychological Distress, Cardiovascular Health, and Allostatic Load in Occupational Settings: Implications for Preventive Medicine, Occupational Health, and Clinical Management. [PDF]

Medicina (Kaunas)
Park EKC, Park WH, Jeon EY.
europepmc   +1 more source

Overcoming platinum resistance by the disulfiram metabolite CuET in novel preclinical models of human carcinomas

Molecular Oncology, EarlyView.
Cisplatin‐resistant cancer cells survive DNA‐damaging platinum‐based treatment yet remain sensitive to CuET‐induced proteotoxic stress. The distinct mechanism of action allows CuET to overcome and eliminate cisplatin‐resistant tumour cells, unless highly expressed metallothioneins (MTs) interfere with CuET, thereby highlighting MT levels as candidate ...
Stefanos Arampatzis, Tereza Buchtová, Jirina Bartkova, Marie Lund Bay, Christoffer Lynge Halvorsen, Zuzana Machacova, Zdenek Skrott, Martin Mistrik, Ekaterina Dulina, Miguel Andujar‐Sanchez, Estrid Høgdall, Tine Henrichsen Schnack, Claus Høgdall, Berit Jul Mosgaard, Marie Boennelycke, Jacob Brink Laursen, Allan Jensen, Susanne K. Kjær, Tuula Kallunki, Robert Strauss, Jiri Bartek   +20 more
wiley   +1 more source