Results 71 to 80 of about 3,768,017 (341)
ABSTRACT Arteriovenous malformations (AVMs) are rare, high‐flow, vascular anomalies that can occur either sporadically or as part of a genetic syndrome. AVMs can progress with serious morbidity and even mortality if left unchecked. Sirolimus is an mTOR inhibitor that is effective in low‐flow vascular malformations; however, its role in AVMs is unclear.
Will Swansson +3 more
wiley +1 more source
Personalizing medicine in silico and in socio [PDF]
Proponents of the emerging field of P4 medicine (defined as personalized, predictive, preventive and participatory) argue that computational integration and analysis of patient-specific “big data” will revolutionize our health care systems, in particular
Green, Sara, Vogt, Henrik
core
ABSTRACT Objective To evaluate the diagnostic yield and utility of universal paired tumor–normal multigene panel sequencing in newly diagnosed pediatric solid and central nervous system (CNS) tumor patients and to compare the detection of germline pathogenic/likely pathogenic variants (PV/LPVs) against established clinical referral criteria for cancer ...
Natalie Waligorski +9 more
wiley +1 more source
GENETICS FOR DIAGNOSTICS IN PREVENTIVE MEDICINE
The sequencing of first human genome followed by rapid development of technologies, that led to significant lowering of costs for genetic analyze and its fast performing, made possible a broad invention of genetic diagnostics methods into clinical ...
I. V. Sidonets, A. N. Meshkov
doaj +1 more source
ABSTRACT Purpose Although not always achieved, complete chemotherapy‐induced nausea and vomiting (CINV) control is the conventional goal of CINV prophylaxis. In this two‐center, mixed‐methods study, we sought to understand the preferences of adolescent patients and family caregivers for CINV control endpoints.
Haley Newman +8 more
wiley +1 more source
Newsletter of the Evans Memorial Department of Clinical Research and Preventive Medicine at University ...
Levinsky, Norman G. +1 more
core
Outcomes of Live Virus Vaccination in Patients With Vascular Anomalies Being Treated With Sirolimus
ABSTRACT Background Live vaccination in patients with vascular anomalies (VA) receiving sirolimus remains controversial due to immunosuppressive effects and theoretical risks. Procedure This single‐center retrospective study included patients with VA less than 4 years old at the start of sirolimus therapy who were incompletely vaccinated.
Svatava Merkle +5 more
wiley +1 more source
Newsletter of the Evans Memorial Department of Clinical Research and Preventive Medicine at University ...
Levinsky, Norman G. +1 more
core
Women’s use of Preventive Primary Care in the Late Postpartum Period [PDF]
The literature has limited data on how women access health care after the traditional postpartum period (postpartum). Modeled after a paper by Bryant (2016), this project assesses the prevalence of primary care visits in the late postpartum period (LPP ...
Price, Katherine, BS +1 more
core +1 more source
ABSTRACT Background Kaposiform lymphangiomatosis (KLA) is an aggressive complex lymphatic anomaly. Patients exhibit malformed lymphatic vessels and often develop hemorrhagic effusions and elevated angiopoietin‐2 (Ang‐2) levels. A somatic NRAS p.Q61R (NRASQ61R) mutation has been associated with KLA.
C. Griffin McDaniel +3 more
wiley +1 more source

