Results 91 to 100 of about 1,228,014 (309)
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
BMJ OpenIntroduction With demographic changes, there is increasing demand for individuals and governments to lengthen working lives. Jobs that are very physically demanding are likely to be more difficult to sustain at older ages.
Karen Walker-Bone +5 more
doaj +1 more source
Preventive medicine: A cure for the healthcare crisis [PDF]
, 2006 Introductory Editorial: Few would dispute the premise that prevention, early detection, and early intervention form the first line of defense on the disease management (DM) continuum.
Clarke, Janice L., Meiris, Deborah
core +1 more source
How can veterinarians be interesting partners for organic dairy farmers? French farmers’ point of views [PDF]
, 2017 Organic dairy farmers must live up to the organic goal of ‘good health’ in respect the organic principles and regulation. Veterinarians could be the organic dairy farmers’ expected sparring partners in reaching this goal but have found difficulties to ...
Bareille, Nathalie +4 more
core +3 more sources
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Slavery and human trafficking international law and the role of the World Bank [PDF]
This paper reviews the international legal framework applicable to the World Bank and member states on contemporary forms of slavery, in particular, trafficking. The Palermo trafficking protocol is specially analyzed.
Perez Solla, Maria Fernanda
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In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Methodological support preventive work of social pedagogues comprehensive schools [PDF]
, 2009 Анотація. У статті автором розглядається методична допомога соціальним педагогам загальноосвітніх закладів ресурсними центрами соціальної сфери у напрямі соціальна профілактика.
Тимошенко, Наталія Євгенівна
core
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Modelling vessel fleet composition for maintenance operations at offshore wind farms [PDF]
, 2018 Chartering a vessel fleet to support maintenance operations at offshore wind farms (OWF's) constitutes one of the major costs of maintaining this type of installations.
García-Fernández, Inmaculada +3 more
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