Results 101 to 110 of about 1,228,014 (309)

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Health Savings Account - Eligible High Deductible Health Plans: Updating the Definition of Prevention [PDF]

open access: yes, 2014
High-deductible health plans (HDHPs) are an important and growing part of the health insurance landscape. By some estimates, as many as 80 percent of large employers may offer an HDHP in 2014.
A. Mark Fendrick   +6 more
core  

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

PREVENTION OF HARASSMENT AT WORK

open access: yesFacta Universitatis, Series: Law and Politics, 2017
In this paper, the author discusses the phenomenon of mobbing, or harassment at the workplace, by focusing on the concept, phenomenological characteristics and types of mobbing, the etiological factors leading to its emergence, and the consequences sustained by victims. Considering the need to have mobbing recognized and legally sanctioned as a form of
openaire   +2 more sources

Power plant preventive maintenance scheduling problem: a 0/1 mixed integer linear programming approach based on cost and reliability to establish an effective policy [PDF]

open access: yes, 2019
The problem addressed is the Power Plant Preventive Maintenance Scheduling. The problem is taken from the power industry and it requires determining the perioThis paper addresses the Power Plant Preventive Maintenance Scheduling Problem.
Perez-Canto, Salvador
core  

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Prevalence and management of severe asthma in primary care: an observational cohort study in Sweden (PACEHR)

open access: yesRespiratory Research, 2018
Background Severe and uncontrolled asthma is associated with increased risk of exacerbations and death. A substantial proportion of asthma patients have poor asthma control, and a concurrent COPD diagnosis often increases disease burden. The objective of
Kjell Larsson   +6 more
doaj   +1 more source

Identify and Report Water Pollution: An Interpretive Guide to Surface Water Conditions of the New Hampshire Coastal Watershed, 2nd edition [PDF]

open access: yes, 2007
This gude was designed to help people who work or recreate outdoors to interpret surface water conditions so that they would recognize a pollution incident and know how to report it.
New Hampshire Estuaries Project
core   +4 more sources

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Home - About - Disclaimer - Privacy