Results 131 to 140 of about 49,315 (282)
The targeted depletion of potential gut pathogens is often challenging because of their intrinsic ability to thrive in harsh gut environments. Earlier, we showed that Campylobacter jejuni (C.
Subhadeep Gupta +6 more
doaj +1 more source
The collapse of ecosystem engineer populations
Humans are the ultimate ecosystem engineers who have profoundly transformed the world's landscapes in order to enhance their survival. Somewhat paradoxically, however, sometimes the unforeseen effect of this ecosystem engineering is the very collapse of ...
Fontanari, José F.
core +2 more sources
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
Transfrontier conservation landscapes, such as the Kavango–Zambezi Transfrontier Conservation Area (KAZA TCA) in southern Africa, play a crucial role in preserving global biodiversity and promoting the sustainable development of local communities ...
Stijn Verschueren +5 more
doaj +1 more source
Population dynamics on random networks: simulations and analytical models
We study the phase diagram of the standard pair approximation equations for two different models in population dynamics, the susceptible-infective-recovered-susceptible model of infection spread and a predator-prey interaction model, on a network of ...
Nunes, Ana, Rozhnova, Ganna
core +2 more sources
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Benefits of Spatial Regulation in a Multispecies System [PDF]
Spatial heterogeneity in multispecies systems affects both ecological interactions and the composition of harvest. A bioeconomic model is used to analyze the nonselective harvest of two stocks with generalized ecological interaction and different ...
Herrera, Guillermo E.
core +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz +6 more
wiley +1 more source
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point +7 more
wiley +1 more source

