Results 131 to 140 of about 49,315 (282)

Selective depletion of Campylobacter jejuni via T6SS dependent functionality: an approach for improving chickens gut health

open access: yesGut Pathogens
The targeted depletion of potential gut pathogens is often challenging because of their intrinsic ability to thrive in harsh gut environments. Earlier, we showed that Campylobacter jejuni (C.
Subhadeep Gupta   +6 more
doaj   +1 more source

The collapse of ecosystem engineer populations

open access: yes, 2017
Humans are the ultimate ecosystem engineers who have profoundly transformed the world's landscapes in order to enhance their survival. Somewhat paradoxically, however, sometimes the unforeseen effect of this ecosystem engineering is the very collapse of ...
Fontanari, José F.
core   +2 more sources

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

High carnivore richness despite human pressure and prey depletion in the south-west of the Kavango–Zambezi Transfrontier Conservation Area

open access: yesOryx
Transfrontier conservation landscapes, such as the Kavango–Zambezi Transfrontier Conservation Area (KAZA TCA) in southern Africa, play a crucial role in preserving global biodiversity and promoting the sustainable development of local communities ...
Stijn Verschueren   +5 more
doaj   +1 more source

Population dynamics on random networks: simulations and analytical models

open access: yes, 2010
We study the phase diagram of the standard pair approximation equations for two different models in population dynamics, the susceptible-infective-recovered-susceptible model of infection spread and a predator-prey interaction model, on a network of ...
Nunes, Ana, Rozhnova, Ganna
core   +2 more sources

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Benefits of Spatial Regulation in a Multispecies System [PDF]

open access: yes
Spatial heterogeneity in multispecies systems affects both ecological interactions and the composition of harvest. A bioeconomic model is used to analyze the nonselective harvest of two stocks with generalized ecological interaction and different ...
Herrera, Guillermo E.
core   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

open access: yesMolecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis   +3 more
wiley   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

Home - About - Disclaimer - Privacy