Results 71 to 80 of about 49,315 (282)

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Towards understanding interactions in a complex world: Design and analysis of multi‐species functional response experiments

Methods in Ecology and Evolution
The functional response describes feeding rates of consumers as a function of resource density. While models for feeding on a single resource species are well studied and supported by a large body of empirical research, consumers feeding on multiple ...
Benjamin Rosenbaum, Jingyi Li, Myriam R. Hirt, Remo Ryser, Ulrich Brose   +4 more
doaj   +1 more source

Range-wide camera traps reveal potential prey species for Javan leopards

Global Ecology and Conservation
Prey depletion poses a threat to large carnivores worldwide. The Javan leopard (Panthera pardus melas), the last remaining apex predator on the Indonesian island of Java, is facing numerous threats from human activities including poaching, habitat loss ...
Andhika C. Ariyanto, Tiejun Wang, Andrew K. Skidmore, Hariyo T. Wibisono, Febri A. Widodo, Asep Y. Firdaus, Yohanes Wiharisno, Nur Koliq, Wahyu Murdyatmaka   +8 more
doaj   +1 more source

Field margins enhance weed seed predation in adjacent fields in early spring

Frontiers in Agronomy, 2023
Seed depletion by granivorous organisms can regulate weeds in arable agriculture. Enhancing this regulation can be achieved by adopting farming practices that favour seed predators.
Sandrine Petit, Benjamin Carbonne, Benjamin Carbonne, Zoé Etcheverria, Nathalie Colbach, David Andrew Bohan   +5 more
doaj   +1 more source

Does foraging efficiency vary with colony size in the fairy martin Petrochelidon ariel? [PDF]

, 2009
Colonial breeding occurs in a wide range of taxa, however the advantages promoting its evolution and maintenance remain poorly understood. In many avian species, breeding colonies vary by several orders of magnitude and one approach to investigating the ...
Alexander, Barrett, Brown, Brown, Brown, Brown, Brown, Brown, Buckley, Danchin, Davis, Higgins, Hoi, Hoogland, Jones, Krebs, Lack, Magrath, Magrath, Magrath, Møller, Nolan, Norberg, Pulliam, Rasbash, Richner, Rolland, Safran, Shields, Snapp, Turner, Turner, Varela, Ward, Weaver, Wittenberger, Witter, Wright   +37 more
core   +2 more sources

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Good times bad times — Unfavorable breeding conditions, more than divorce, lead to increased parental effort and reduced physiological condition of northern gannets

Frontiers in Ecology and Evolution, 2023
Decreased productivity in long-lived bird species is linked to prey depletion in marine ecosystems. Seabirds, however, exhibit behavioral flexibility at individual level to prevent this outcome.
David Pelletier, David Pelletier, Pierre Blier, François Vézina, Magella Guillemette   +4 more
doaj   +1 more source

Human THO–Sin3A interaction reveals new mechanisms to prevent R-loops that cause genome instability [PDF]

, 2017
R-loops, formed by co-transcriptional DNA–RNA hybrids and a displaced DNA single strand (ssDNA), fulfill certain positive regulatory roles but are also a source of genomic instability.
Aguilera López, Andrés, Bayona Feliu, Aleix, Luna Varo, Rosa María, Pérez Calero, Carmen, Salas Armenteros, Irene, Tumini, Emanuela   +5 more
core   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Lion and spotted hyena distributions within a buffer area of the Serengeti-Mara ecosystem

Scientific Reports, 2021
Most large carnivore populations are declining due to anthropogenic activities including direct persecution, prey depletion, habitat loss and degradation.
Stanslaus B. Mwampeta, Clay M. Wilton, Imani J. Mkasanga, Lusato M. Masinde, Peter S. Ranke, Eivin Røskaft, Robert Fyumagwa, Jerrold L. Belant   +7 more
doaj   +1 more source