Results 91 to 100 of about 139,654 (335)

Mechanical, chemical, structural analysis and comparative release of PDGF-AA from L-PRF, A-PRF and T-PRF - an in vitro study

Biomaterials Research, 2020
Background Platelet concentrates have been popularly used in regenerative periodontal therapy as they are autologous in origin and they provide a supernatural concentration of platelets, growth factors and leukocytes.
Shravanthy Ravi, M. Santhanakrishnan
semanticscholar   +1 more source

First Generation Proteolysis Targeting Chimeras (PROTACs) for the Treatment of Progeria

Advanced Science, EarlyView.
We report the first PROTACs designed to degrade progerin, introducing a novel therapeutic approach for progeria. The best compound, UCM‐18142, significantly reduces progerin levels and improves key disease phenotypes in patient‐derived cells and in the LmnaG609G/G609G mouse model, paving the way for new treatment strategies targeting the root cause of ...
Jon Macicior‐Michelena, Marcelino Telechea, Daniel Fernández, Alba García‐Martín, Ángeles Canales, Silvia Ortega‐Gutiérrez   +5 more
wiley   +1 more source

Generative AI‐Driven Accelerated Discovery of Passivation Molecules for Perovskite Solar Cells

Advanced Science, EarlyView.
A generative artificial intelligence (AI) framework combining a discriminative machine learning model (SMILES‐X) and a generative language model (GPT‐2) autonomously discovers new molecular passivators for perovskite solar cells (PSCs). Through an iterative design loop, over 100 000 candidates are generated and screened, and randomly selected molecules
Adroit T. N. Fajar, Guillaume Lambard, Jessie Manopo, Ruili Guo, Kevin Septioga, Rizfi F. Pari, Toshinori Matsushima, Zhanglin Guo   +7 more
wiley   +1 more source

An Efficient Polyphase Filter Based Resampling Method for Unifying the PRFs in SAR Data

, 2017
Variable and higher pulse repetition frequencies (PRFs) are increasingly being used to meet the stricter requirements and complexities of current airborne and spaceborne synthetic aperture radar (SAR) systems associated with higher resolution and wider ...
Amelung, Falk, Premaratne, Kamal, Torres, Yoangel, Wdowinski, Shimon   +3 more
core   +1 more source

scResponse: A Rank‐Based Method for Identifying Cell States That Contribute to Immunotherapy Response by Single‐Cell Data

Advanced Science, EarlyView.
Although the tumor microenvironment is known to shape immunotherapy response, its key determinants remain elusive, underscoring the critical need for single‐cell resolution analytical frameworks. We present scResponse, an efficient algorithm to quantify single‐cell responses to immunotherapy. By capturing diverse cellular subtypes and states associated
Qi Dong, Haijun Huang, Yuxiu Wang, Bo Jiang, Yuzheng Chen, Huanhuan Xu, Jing Ren, Shengnan Guo, Tianhao Li, Mingjie Zhang, Tianyu Zhai, Wenbo Yang, Kaidong Liu, Cheng Lyu, Jingxuan Kang, Mingshuo Zhang, Yupeng Lu, Binghui Si, Shujun Cao, Dandan Xu, Zong Chen, Dapeng Hao   +21 more
wiley   +1 more source

Transition Property for $\alpha$-Power Free Languages with $\alpha\geq 2$ and $k\geq 3$ Letters

, 2020
In 1985, Restivo and Salemi presented a list of five problems concerning power free languages. Problem $4$ states: Given $\alpha$-power-free words $u$ and $v$, decide whether there is a transition from $u$ to $v$. Problem $5$ states: Given $\alpha$-power-
A Carpi, A Restivo, AM Shur, AM Shur, D König, EA Petrova, F Dejean, J Currie, J Shallit, J-J Pansiot, JM Ollagnier, M Rao   +11 more
core   +1 more source

Independent Prognostic Significance of Perforation in Colorectal Cancer: Insights From a Propensity Score‐Matched Cohort Study

Annals of Gastroenterological Surgery, EarlyView.
Perforated colorectal cancer (PCC) is considered to have a poor prognosis; however, it remains unclear whether this is attributable to perforation itself or to perforation‐related clinicopathological factors. In this study, we analyzed prognosis using propensity score matching with perforation‐related factors and demonstrated that perforation is an ...
Yoshiaki Fujii, Shuhei Ueno, Yoshinaga Aoyama, Hiroyuki Imafuji, Takahisa Hirokawa, Hirotaka Miyai, Masahiro Kimura, Kenji Kobayashi, Shuji Takiguchi   +8 more
wiley   +1 more source

Echo tracker/range finder for radars and sonars [PDF]

, 1982
An echo tracker/range finder or altimeter is described. The pulse repetition frequency (PFR) of a predetermined plurality of transmitted pulses is adjusted so that echo pulses received from a reflecting object are positioned between transmitted pulses ...
Constantinides, N. J.
core   +1 more source

The Effects of Leukocyte-Platelet Rich Fibrin (L-PRF) on Suppression of the Expressions of the Pro-Inflammatory Cytokines, and Proliferation of Schwann Cell, and Neurotrophic Factors

Scientific Reports, 2020
This study evaluates the use of L-PRF as an autologous scaffold in nerve regeneration, and Schwann cells (SCs) proliferation and secretion of neurotrophic factors and its anti-inflammatory effect on SC Porphyromonas Gingivalis-Lipopolysaccharide (PG-LPS)-
Zhanqi Wang, Mahmoud Mudalal, Yue Sun, Yiping Liu, Jia Wang, Yao Wang, Xiaolin Sun, Yanmin Zhou   +7 more
semanticscholar   +1 more source

Influence of Wall Deformation Structure on the Liquid Film Flow Behavior Under Turbulent Conditions

Asia-Pacific Journal of Chemical Engineering, EarlyView.
ABSTRACT To explore the influence of typical wall deformation structure in the scrubbing‐cooling tube on the liquid film, this paper studied the liquid film flow behavior on the riblet walls with representative riblet radii and compared them with the flat wall. Under different liquid film Reynolds numbers (Rel = 8.3 × 103 ~ 3.14 × 104), the liquid film
Qian Liu, Yifei Wang, Jie Zeng, Zongren Pan, Dawei Feng, Guangsuo Yu   +5 more
wiley   +1 more source