Results 111 to 120 of about 38,367 (265)

Když zákon mlčel: § 7 OZO pohledem právní vědy a Nejvyššího soudu Československé republiky v první polovině 20. století

open access: yesČasopis pro Právní Vědu a Praxi
Článek se věnuje právní vědě a § 7 OZO v první polovině 20. století s následným zaměřením na judikaturu Nejvyššího soudu. Ustanovení § 7 upravovalo (a v ABGB stále upravuje) výplň mezer v zákoně, tedy situaci, kdy právní případ nelze rozhodnout subsumpcí
Lukáš Maliňák
doaj  

Deciphering diverse cell‐death patterns to predict the prognosis and potential therapy target of hepatocellular carcinoma patients

open access: yesVIEW, EarlyView.
Abstract Ninety percent of all primary liver malignancies are hepatocellular carcinomas (HCC), making liver cancer the third most common cause of cancer‐associated mortality. Different patterns of programmed cell death (PCD) are crucial for the survival of tumors, and they might serve as a prognostic marker for HCC.
Lin Ding   +10 more
wiley   +1 more source

PPM1G‒MET axis sustains AKT signaling to drive Twist‐associated EMT and drug resistance in hepatocellular carcinoma

open access: yesVIEW, EarlyView.
Hepatocellular carcinoma (HCC) is frequently resistant to targeted therapies. We identify protein phosphatase Mg2+/Mn2+‐dependent 1G (PPM1G) as a key phosphatase that stabilizes mesenchymal‐epithelial transition factor (MET) by inhibiting its ubiquitination, thereby sustaining protein kinase B (AKT) signaling and promoting Twist‐mediated epithelial ...
Weixun Wu   +8 more
wiley   +1 more source

Regenerative properties of platelet-rich fibrin: application in oral lesions

open access: yesКлинический разбор в общей медицине
Aim. Oral mucosal lesions (OMLs) are a common pathology that significantly reduces quality of life. Platelet-rich fibrin (PRF) is a promising autologous biomaterial; however, its effectiveness in OM pathology requires systematic evaluation.
Vitalii B. Kaliberdenko   +7 more
doaj   +1 more source

Progress in bone tissue engineering biomaterials: Development, challenges, and prospects

open access: yesVIEW, EarlyView.
Scheme 1 Application of biomaterials in immunomodulation during bone tissue engineering. Abstract Bone defect repair remains a major clinical challenge in orthopedics. Over 2 million cases caused by trauma, tumors, and other factors occur annually, with large‐scale defects posing a particular bottleneck due to limited self‐healing capacity.
Yuanbin Zhang   +7 more
wiley   +1 more source

From Nouns and Adjectives to Verbs: Base Effects on the Grammatical Behaviour of Denominal Verbs in Ancient Greek1

open access: yesTransactions of the Philological Society, EarlyView.
Abstract This paper investigates the role of semantic features of noun and adjective bases in determining the grammatical behaviour of Ancient Greek denominal and deadjectival verbs in *‐ye/o‐. The paper adopts a lexicalist framework (Rappaport Hovav & Levin 1998) and examines how the event schema, actionality, telicity and voice of derived verbs are ...
Carolina Marescotti
wiley   +1 more source

Opening the Door Wider to Community Support of People With Serious Mental Illnesses: What States Can Learn From the IDD Experience

open access: yesThe Milbank Quarterly, EarlyView.
Policy Points The federal government should provide states with authorities under Medicaid that allow greater use of home and community‐based services for people with serious and persistent mental illness. This requires deemphasizing authorities that require budget neutrality in a post‐institutionalization world (Section 1115 waivers) and relying on ...
HAROLD POLLACK   +2 more
wiley   +1 more source

NTAQ1 Promotes Hepatocellular Carcinoma Growth by Facilitating the Protein Degradation of the Tumor Suppressor PRDM2

open access: yesCancer Science, EarlyView.
Copy number variation analysis in The Cancer Genome Atlas identified NTAQ1 as a potential driver of HCC progression. NTAQ1 accelerates tumor growth by promoting the degradation of the tumor suppressor protein PRDM2, thereby impairing DNA repair and suppressing apoptosis. These findings indicate that NTAQ1 could be a valuable target for the treatment of
Tomohiko Ikehara   +21 more
wiley   +1 more source

Parents With Substance Use Disorder in the Holding Tight Treatment System: Intervention Effectiveness and Moderating Effects

open access: yesChild &Family Social Work, EarlyView.
ABSTRACT Parents with substance use disorder have multiple risks affecting their parenting. Mental health problems and adverse childhood experiences (ACEs) with problems in emotion regulation and adult attachment insecurity may impair the early interaction with the infant.
Saara J. Salo   +4 more
wiley   +1 more source

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