Results 221 to 230 of about 2,752,713 (308)

Cost-effectiveness of ramucirumab plus paclitaxel as maintenance therapy for patients with advanced HER2-negative gastric or gastroesophageal junction cancer. [PDF]

Front Oncol
Li D, Zhao X, Jia H, Cui R, Cao A, Huo L.   +5 more
europepmc   +1 more source

MiR‐513a promotes human erythroid differentiation by modulating c‐Jun

FEBS Open Bio, EarlyView.
During early human erythropoiesis, miR‐513a promoted erythroid differentiation in primary human CD34+ hematopoietic stem‐progenitor cells and human TF‐1 erythroleukemic cells by indirectly decreasing c‐Jun and phospho‐c‐Jun expression, which are associated with increased GATA1 expression.
MinJung Kim, Brittany Taylor, Shannon Bolten, Christian L. Eberly, Mahliya Abdurahman, T. Michael Creed, Acong Yang, Taylor L. Hatchet, Tristan Dyson, Shuo Gu, Curt I. Civin, Tami J. Kingsbury   +11 more
wiley   +1 more source

Chinese Patent Medicines for Cervical Spondylosis: A Comprehensive Review and Current Status of Clinical Research. [PDF]

Int J Gen Med
Fan Y, Sun Y, Lou H, Ji Y, Chang T, Cui Y, Yao J, Shang Q.   +7 more
europepmc   +1 more source

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

FEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Two-period e-commerce platforms operation strategies considering the difference in product quality perception. [PDF]

PLoS One
Xie B, Guo Q, Cheng Y, Niu M.
europepmc   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Collective Evidence on Behavioral Interventions Targeting Carbon Pricing Support: A Many-Designs Approach with 55 Studies

Huber J, Holzknecht A, Schwaiger R, Blanco E, Kirchler M.   +4 more
europepmc   +1 more source

Impact of sugary drink taxes on beverage calories purchased in a national fast food restaurant chain: A quasi-experimental study. [PDF]

PLoS Med
Rummo PE, Echenique JA, Wu E, Mijanovich T, Desai SM, Bragg MA, Weitzman BC, Elbel B.   +7 more
europepmc   +1 more source

State Control of Milk Prices

American Journal of Public Health and the Nations Health, 1934
openaire   +3 more sources

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source