Results 111 to 120 of about 4,934,009 (308)
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Irving Fisher and Index Number Theory [PDF]
There are four main approaches to bilateral index number theory: the fixed basket, stochastic, test and economic approaches. The paper reviews the contributions of Irving Fisher to these approaches to index number theory which are still in use today. The
Diewert, Erwin
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Marketing research of pricing factors in a competitive market [PDF]
Marketing i Menedžment Innovacij, 2015 The aim of the article. The aim of the article is the marketing research of the influence of macroeconomic factors on a weighted average price of wheat bread in a competitive market. The results of the analysis.
N.V. Biloshkurska
doaj
FEBS Letters, EarlyView.Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani +3 more
wiley +1 more source
Scanner Data, Time Aggregation and the Construction of Price Indexes [PDF]
The impact of weekly, monthly and quarterly time aggregation on estimates of price change is examined for nineteen different supermarket item categories over a fifteen month period using scanner data.
Ivancic, Lorraine +2 more
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Dispariti of prices in the agrarian economy of Russia
Путеводитель предпринимателя, 2020 In the basis of the presented analysis of branch features of pricing in agriculture, dynamics of price indices for manufactured goods and agricultural products it is justified that the price parity violation largely determines the current development of ...
N. R. Amirova, L. V. Sargina
doaj
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
Substitution Biases in Price Indexes during Transition [PDF]
The rapidly changing environment of the transition may create special problems for calculation of index numbers that require a fixed basket of goods and retail outlets.
Jan Hanousek, Randall K. Filer
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Prioritize Effective Financial Factors on Price Stock in Tehran Stock Exchange with Using TOPSIS Method [PDF]
تحقیقات مالی, 2009 The goal of this research was prioritize effective financial factors on price stock in Tehran stock exchange with using TOPSIS method. Based on, it was reviewed literature and interviews and specially questionnaire obtain, effective financial factors to ...
Mojtaba Pakdin Amiri +2 more
doaj
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source