Results 61 to 70 of about 3,579,788 (304)

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

The Price of Stability in Selfish Scheduling Games

open access: yes2007 IEEE/WIC/ACM International Conference on Intelligent Agent Technology (IAT'07), 2007
Game theory has gained popularity as an approach to analysing and understanding distributed systems with self-interested agents. Central to game theory is the concept of Nash equilibrium as a stable state (solution) of the system, which comes with a price − the loss in efficiency.
Lucas Agussurja, Hoong Chuin Lau
openaire   +5 more sources

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Performance of Mexico’s wholesale electricity market: challenges for an efficient energy transition

open access: yesDyna
This article analyzes the performance of Mexico’s Wholesale Electricity Market (MEM from the Spanish acronym) through a comparison with international markets such as Chile, Brazil, the United States, the United Kingdom, Scandinavian countries, South ...
Rubén Omar Orduño-Melchor   +3 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Achieving price stability: a 1993 report card [PDF]

open access: yes
The primary goal of Federal Reserve monetary policy is to foster maximum sustainable growth in the U.S. economy by achieving price stability over time. Although considerable progress toward price stability has been made since the early 1980s, inflation ...
George A. Kahn
core  

Aggregate Price Shocks and Financial Stability: The United Kingdom 1796-1999 [PDF]

open access: yes
This paper investigates the impact historically of aggregate price shocks on financial stability in the United Kingdom. We construct an annual index of U.K.
Michael D. Bordo   +2 more
core   +2 more sources

Exchange Rates, Inflation, and Nickel Export Value: A Comparative Panel Study

open access: yesJIET (Jurnal Ilmu Ekonomi Terapan)
Objective: The present study analyzes the impact of the exchange rate and inflation on nickel exports from three prominent producers in the Asia-Pacific region with disparate economic development levels.
Tarizyah Amanda   +4 more
doaj   +1 more source

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

open access: yesFEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani   +3 more
wiley   +1 more source

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