Results 101 to 110 of about 980,585 (325)
Targeting DESI2 as a Novel Therapeutic Strategy for JAK2‐Mutant Leukemias
Advanced Science, EarlyView.Mass spectrometry‐based proteomics identify DESI2 as a novel component of the JAK2‐V617F complex, which associates with and stabilizes mutant JAK2 through deSUMOylation and deubiquitination, therefore promoting JAK2 mutant cell growth and MPN disease onset in vivo.
Husheng Mei +32 more
wiley +1 more source
Hope, Ethnic Pride, and Academic Achievement: Positive Psychology and Latino Youth
, 2014 Previous studies have found that hope has beneficial effects in athletics, academics, physical health, and mental well being in majority populations. Given the challenges Latino youth face in the United States, ethnic identity and hope may be a powerful ...
Berenson, Kathy R. +2 more
core +1 more source
A Preliminary Analysis of Text Coverage and Extensive Reading of Chinese ESL Learners-- Range Analysis of The Little Prince and Pride and Prejudice [PDF]
, 2021 Jiayu Zhuo
openalex +1 more source
Mechanism‐Driven Screening of Membrane‐Targeting and Pore‐Forming Antimicrobial Peptides
Advanced Science, EarlyView.To combat antibiotic resistance, this study employs mechanism‐driven screening with machine learning to identify pore‐forming antimicrobial peptides from amphibian and human metaproteomes. Seven peptides are validated, showing minimal toxicity and membrane disruption.
Jiaxuan Li +9 more
wiley +1 more source
The principle objective of the kinds of demonstration tests that are discussed is to try to verify whether or not carbon fibers that are released by burning composite parts in an aircraft-fuel fires can produce failures in electrical equipment.
Pride, R. A.
core +1 more source
Raising a sense of national pride in pupils with the help of folklore
, 2021 Abdullayev Mukhammadimin Egamberdiyevich
openalex +1 more source
GOT1 Inhibition Induces Extracellular Matrix Remodeling in Pancreatic Cancer
Advanced Science, EarlyView.Using tumor tissue engineering, we recreated pancreatic cancer and found that inhibiting glutamic‐oxaloacetic transaminase 1 (GOT1) induces extracellular matrix remodeling and secretome rewiring, as well as promotes cell death. ABSTRACT Pancreatic cancer cells rely on glutamine to sustain their survival in the stiff and poorly vascularized tumor ...
Rodrigo Curvello +10 more
wiley +1 more source
CID-720 aircraft Langley Research Center preflight hardware tests: Development, flight acceptance and qualification [PDF]
The testing conducted on LaRC-developed hardware for the controlled impact demonstration transport aircraft is discussed. To properly develop flight qualified crash systems, two environments were considered: the aircraft flight environment with the focus
Pride, J. D.
core +1 more source