Results 121 to 130 of about 1,022,380 (384)
METTL10‐Mediated PIAS3 Methylation Links Purine Metabolism to Gastric Cancer Progression
METTL10‐mediated methylation of PIAS3 at K442 inhibits its SUMO E3 ligase activity toward MITF. This reduces MITF SUMOylation and subsequent RNF4‐mediated ubiquitination, leading to MITF protein accumulation and gastric cancer progression. Abstract Metabolic dysregulation plays a significant role in the development of gastric cancer (GC).
Jinshui Tan +20 more
wiley +1 more source
Work-life balance and its relationship with organizational pride and job satisfaction
Purpose – The purpose of this paper is to explore the relationship between work-life balance, organizational pride and job satisfaction. When evaluating employee work-life balance the present paper takes into consideration two relevant antecedents ...
M. Mas-Machuca +2 more
semanticscholar +1 more source
Measuring the Welfare Effects of Shame and Pride
Public recognition is frequently used to motivate desirable behavior, yet its welfare effects—such as costs of shame or gains from pride— are rarely measured.
Luigi Butera +3 more
semanticscholar +1 more source
The quantitative proteomic and phosphoproteomic profiling reveals dynamic phosphorylation regulation of sperm morphogenesis. Kinase‐substrate phosphorylation network and phosphorylation module analysis, followed by in vivo knockdown and knockout analysis, identify TTBK2 and CSNK1G1 as key regulators of morphogenesis, including head, flagellar, and ...
Tianyu Zhu +25 more
wiley +1 more source
Urgent action is required to address threats to ecosystems around the world. Coral reef ecosystems, like the Great Barrier Reef (GBR), are particularly vulnerable to human impacts such as coastal development, resource extraction, and climate change ...
Jeremy A. Goldberg +5 more
doaj +1 more source
Hydrogen‐Deuterium Exchange Mass Spectrometry for Molecular Glue Characterization
Molecular glues that stabilize protein–protein interactions are challenging to identify. Here, hydrogen‐deuterium exchange mass spectrometry can show and reveal gluing mechanisms that vary between protein binding partners. Abstract Molecular glues are powerful bioactive molecules that stabilize protein–protein interactions.
Danielle F. Kay +3 more
wiley +1 more source
Lifang Chen,1 Guilan Yu,1 Bo Fu2 1School of Business and Management, Jilin University, Changchun, People’s Republic of China; 2School of Management, Guangzhou University, Guangzhou, People’s Republic of ChinaCorrespondence: Bo Fu, School of Management ...
Chen L, Yu G, Fu B
doaj
Conservation of the Lion: Preventing an Africa without the African Lion [PDF]
The African lion (Panthera leo) population is diminishing rapidly, approximately 43 percent since 1993. The species is currently listed as vulnerable by the International Union for Conservation of Nature (IUCN).
Kamyk, Courtney
core +2 more sources
This work leverages the level of carbon supersaturation in the metallic constituents during particle formation to regulate nanoparticle morphology, structure, and composition distribution. The solvent‐dependent (C/(C+O)) ratio and the relative kinetics of the competing reactions of carbon shell formation, coalescence of metallic constituents, and ...
Varatharaja Nallathambi +7 more
wiley +1 more source

