Results 231 to 240 of about 4,700,345 (286)

Genetics of Primary Adrenal Insufficiency Beyond CAH in Saudi Arabian Population. [PDF]

Mol Genet Genomic Med
Al-Hamed MH, Qari A, Alrayes L, Alotaibi M, Al Masseri Z, Alotaibi A, AlAshwal A, AlHassnan ZN, Alsagheir A.   +8 more
europepmc   +1 more source

Epigenetic Dysregulation of Somatostatin Receptors (SSTR) 1–5 and Therapeutic Implications in Neuroendocrine and Non‐Neuroendocrine Malignancies

International Journal of Cancer, Volume 159, Issue 11, Page 2633-2652, 1 December 2026.
ABSTRACT Somatostatin receptors (SSTR) mediate the antiproliferative, antisecretory, and proapoptotic effects of somatostatin and its synthetic analogs. Their surface expression on neuroendocrine tumor (NET) cells is required for somatostatin analog therapy and radiopharmaceutical therapy (RPT).
Neeraj Kumari, Pablo Hoffmann, Laura Reichl, Maximilian Schmutz, Nina Fischer, Thi Tuong Vi Dang, Fulvia Ferrazzi, Pascal Johann, Michaela Kuhlen, Constantin Lapa, Rainer Claus   +10 more
wiley   +1 more source

From Prevention to Healthy Longevity: Evaluating the Multi‐Systemic Effects of Physical Activity and Lifestyle Behaviours in Women

Reproductive, Female and Child Health, Volume 5, Issue 4, December 2026.
ABSTRACT Purpose Despite spending more on healthcare than any other high‐income nation, the United States faces comparatively poor life expectancy outcomes, primarily due to non‐compliance with preventable and modifiable lifestyle behaviours. This review evaluates the multi‐systemic benefits of physical activity, exercise, diet, weight management and ...
Darah Dilmaghani, Mary Collins, Gloria A. Bachmann   +2 more
wiley   +1 more source

Total Neoadjuvant Treatment for Esophageal Adenocarcinoma With Oligometastases: TNT‐OES‐1 Trial

International Journal of Cancer, Volume 159, Issue 10, Page 2552-2561, 15 November 2026.
Total neoadjuvant therapy could combine the potentially strong systemic effect of FLOT chemotherapy with the good locoregional control of CROSS chemoradiotherapy. While total neoadjuvant therapy is increasingly used in rectal cancer, its potential in gastroesophageal cancer remains largely unexplored.
Charlène J. van der Zijden, Tamara J. Huizer, Ben M. Eyck, Ate van der Gaast, Leni van Doorn, Marjolein Y. V. Homs, J. Jan B. van Lanschot, Joost J. M. E. Nuyttens, Lindsey Oudijk, Manon C. W. Spaander, Bas P. L. Wijnhoven, Bianca Mostert, Sjoerd M. Lagarde   +12 more
wiley   +1 more source

Multi‐Organ Inflammatory and Endocrine Crosstalk Shapes the Early Brain Response to Combined Burn and Blast Injury

The FASEB Journal, Volume 40, Issue 21, 15 November 2026.
Concomitant burn injury and blast‐induced mild TBI lead to a magnified neuroimmune response shaped by endocrine stress‐related pathways and IL‐1R1‐dependent inflammatory signals, which also produce cytokine‐mediated impairment of erythropoiesis. These integrated systemic and CNS responses illustrate how inflammation, hematopoietic adaptation, and early
Hana C. Schwierling, Satarupa Sengupta, John G. Noel, Christopher J. O'Connell, Andrew S. Potter, Mike Adam, Matthew J. Robson, Jason C. Gardner   +7 more
wiley   +1 more source

PRAME predicting outcome in uveal melanoma

The Journal of Pathology: Clinical Research, Volume 12, Issue 6, November 2026.
Abstract Uveal melanoma (UM) is the most common primary intra‐ocular malignancy in adults and carries a high risk of metastatic disease, affecting approximately 50% of patients despite advances in local tumour control. PRAME (PReferentially expressed Antigen in MElanoma) has emerged as a marker for metastatic risk; however, evidence is largely derived ...
Sally Owens, Naomi Walsh, Noel Horgan, Patrick Murtagh, Katie Hanratty, Grainne Finegan, Laura Ivers, John Crown, Susan Kennedy   +8 more
wiley   +1 more source

Efficacy of High‐Frequency Transcranial Magnetic Stimulation Therapy for Depression With Insomnia Symptoms: A Systematic Review and Meta‐Analysis Based on Randomized Controlled Trials

Brain and Behavior, Volume 16, Issue 11, November 2026.
It summarizes the key findings: improves sleep quality (SMD0.97) and depressive symptoms(SMD0.61) in depression‐related insomia ABSTRACT Background This meta‐analysis evaluated the efficacy of high‐frequency repetitive transcranial magnetic stimulation (HF‐rTMS) targeting the left dorsolateral prefrontal cortex (DLPFC) in patients with comorbid ...
Wenqing Yang, Songbin Chen, Xiaotong Li, Junhui Chen, Li Li, Jin Yu   +5 more
wiley   +1 more source

Insights Into Pediatric Non-congenital Adrenal Hyperplasia: A Review Based on 5 Different Rare Cases with Primary Adrenal Insufficiency. [PDF]

Turk Arch Pediatr
Cetin SK, Siklar Z, Ozsu E, Aycan Z, Berberoglu M.   +4 more
europepmc   +1 more source

Primary adrenal insufficiency an hemochromatosis

Clinical and Experimental Hepatology, 2017
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