Results 221 to 230 of about 55,893 (295)

Sexual precocity in a 4 year old boy [PDF]

open access: yes, 2010
Connell, J.M.   +4 more
core   +1 more source

Carrier screening in the reproductive setting—Are there medical implications for the heterozygote?—A guide for clinicians

open access: yesPregnancy, Volume 2, Issue 3, May 2026.
Abstract Carrier screening for genetic conditions performed preconception or during pregnancy allows identification of fetal risk for inherited autosomal recessive and X‐linked conditions. The goal is to identify at‐risk patients/couples and offer them reproductive options such as preimplantation genetic diagnosis, prenatal testing, or targeted newborn
Emily B. Rosenfeld   +5 more
wiley   +1 more source

Early‐life Giardia infection and behavioural dysregulation in two dogs: A case‐based exploration of the gut microbiome–brain axis

open access: yesVeterinary Record Case Reports, Volume 14, Issue 2, May 2026.
Abstract This case report describes two dogs exhibiting severe behavioural problems, both diagnosed with early‐life giardiasis and raised in environments lacking adequate maternal care and socialisation. Both dogs experienced chronic gastrointestinal and dermatological issues, as well as prolonged early‐life stress, which likely contributed to ...
Daniëlle Hartman   +3 more
wiley   +1 more source

Genetics of Primary Adrenal Insufficiency Beyond CAH in Saudi Arabian Population. [PDF]

open access: yesMol Genet Genomic Med
Al-Hamed MH   +8 more
europepmc   +1 more source

Atypical metastatic osteosarcoma pattern in a dog: Lymphatic, neurovascular and subcutaneous metastasis

open access: yesVeterinary Record Case Reports, Volume 14, Issue 2, May 2026.
Abstract A 6‐year‐old, spayed, female labrador retriever was presented with left distal radial swelling. Imaging, cytology and biopsy identified an aggressive radial lesion with metastasis to the left axillary lymph node, and a diagnosis of presumptive osteosarcoma was made.
Veronica Perez‐Rodriguez   +4 more
wiley   +1 more source

Predictive Value of Circulating Tumor Cells in Neoadjuvant Chemoimmunotherapy for Non‐Small Cell Lung Cancer

open access: yesThoracic Cancer, Volume 17, Issue 9, May 2026.
Preoperative CK+ CTC monitoring may serve as a promising adjunct to conventional imaging for predicting pathological response in patients receiving neoadjuvant chemoimmunotherapy. Our exploratory findings suggest that systemic CTC dissemination is associated with a microenvironmental convergence of local hypoxia and attenuated immune signaling ...
Jianyi Yang   +11 more
wiley   +1 more source

Kisspeptin as a test of hypothalamic dysfunction in pubertal and reproductive disorders

open access: yesAndrology, Volume 14, Issue 4, Page 1002-1016, May 2026.
Abstract The hypothalamic–pituitary–gonadal axis is regulated by the gonadotropin‐releasing hormone pulse generator in the hypothalamus. This is comprised of neurons that secrete kisspeptin in a pulsatile manner to stimulate the release of GnRH, and, in turn, downstream gonadotropins from the pituitary gland, and subsequently sex steroids and ...
Aureliane C. S. Pierret   +5 more
wiley   +1 more source

Opioids in breast cancer: Between analgesia and modulation of tumour progression

open access: yesBritish Journal of Pharmacology, Volume 183, Issue 9, Page 1727-1746, May 2026.
Preclinical investigations consistently demonstrate that activation of μ‐opioid receptors and δ‐opioid receptors promote proliferation, migration, angiogenesis, epithelial‐mesenchymal transition, acquisition of cancer stem cell phenotypes, and chemoresistance.
Marianna Ciwun   +2 more
wiley   +1 more source

University Exams and Psychosocial Stress: Effects on Cortisol Rhythmicity in Students

open access: yesClinical Endocrinology, Volume 104, Issue 5, Page 436-442, May 2026.
ABSTRACT Background University exams are recognised as naturalistic stressors that may elicit psychosocial and physiological responses in students. This pilot study investigated the short‐ and long‐term effects of exam‐related stress on hypothalamic–pituitary–adrenal (HPA) axis activity, focusing on cortisol production and rhythmicity.
Filipy Borghi   +6 more
wiley   +1 more source

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