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Primary T-cell lymphoma of the adrenal glands with adrenal insufficiency
Human Pathology, 1986A 74-year-old man with bilateral adrenal gland masses presented with adrenal insufficiency. Biopsies and immunohistochemical staining of both masses revealed a large cell T-cell lymphoma. The lymphoma subsequently involved the central nervous system. A review of the literature disclosed that this is an extremely uncommon presentation of lymphoma.
Ricardo V. Lloyd +2 more
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Mineralocorticoid substitution and monitoring in primary adrenal insufficiency [PDF]
Best Practice & Research Clinical Endocrinology & Metabolism, 2015 Patients with primary adrenal insufficiency usually show pronounced impairment of aldosterone secretion and, therefore, require also mineralocorticoid replacement for full recovery. Clinical signs of mineralocorticoid deficiency comprise hypotension, weakness, salt craving and electrolyte disturbances (hyperkalemia, hyponatremia).
Wolgang Oelkers +3 more
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The expanding world of primary adrenal insufficiencies
European Journal of Endocrinology, 1997The past few years have seen a phenomenal increase in our understanding of three genetic causes of primary adrenal and gonadal hormone deficiency. Lin and coworkers reported in 1995 (1) that patients with congenital lipoid adrenal hyperplasia have mutations of the steroidogenic acute regulatory protein.
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Primary Adrenal Insufficiency Manifesting as Malignant Lymphoma
Archives of Internal Medicine, 1983Primary adrenal insufficiency associated with a hematologic malignant neoplasm is a rare entity. Most malignant neoplasms with metastases to the adrenal gland are secondary to solid carcinomas of the lung and breast. A 55-year-old man was seen with clinical and biochemical evidence of primary adrenal insufficiency as the initial manifestation of his ...
James M. Falko +4 more
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A Patient with Concurrent Primary Hyperaldosteronism and Adrenal Insufficiency
The American Journal of the Medical Sciences, 2004A 73-year-old man with history of longstanding primary hyperaldosteronism developed adrenal insufficiency after he ruptured an abdominal aortic aneurysm and had a prolonged hypotensive episode. The patient presented as a diagnostic dilemma with recurrent hypotensive episodes and hypokalemia.
Francisco Puentes +2 more
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Primary adrenal insufficiency in children: Diagnosis and management
Best Practice & Research Clinical Endocrinology & Metabolism, 2018Primary adrenal insufficiency (PAI) is a life-threatening disorder of adrenal cortex which is characterized by deficient biosynthesis of glucocorticoids, with or without deficiency in mineralocorticoids and adrenal androgens. Typical manifestations of primary adrenal insufficiency include hyperpigmentation, hypotension, hypoglycaemia, hyponatremia with
Tulay Guran, Tarik Kirkgoz
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Fertility and Pregnancy in Primary Adrenal Insufficiency in Germany
Hormone and Metabolic Research, 2016Autoimmune adrenalitis (AA) and congenital adrenal hyperplasia (CAH) are the most common reasons for acquired and monogenetic primary adrenal insufficiency. Both concern women in their fertile years. The aim of the work was to examine fertility rates, pregnancy outcome, and children's characteristics in AA and CAH patients in 2 German endocrine centers.
Hanna Remde +3 more
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Sella Turcica Enlargement and Primary Adrenal Insufficiency
Annals of Internal Medicine, 1978Excerpt Sella turcica enlargement is a well-established complication of prolonged, primary hypothyroidism (1, 2).
Gordon H. Williams +2 more
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Primary Adrenal Insufficiency and Hyperpigmentation
The American Journal of Medicine, 2023Manidipa Majumder +2 more
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Update on genetics of primary adrenal insufficiency
Current Opinion in Endocrine and Metabolic Research, 2019Abstract Primary adrenal insufficiency (PAI) is a rare disorder almost exclusive of genetic origin when occurring early in life. Next-generation sequencing has revealed novel forms of isolated and syndromic forms of PAI in unsuspected genes. Nicotinamide nucleotide transhydrogenase (NNT) mutations discovered in many individuals with familial ...
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