Results 171 to 180 of about 5,663,878 (222)
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Subclinical primary aldosteronism

Best Practice and Research in Clinical Endocrinology and Metabolism, 2012
Screening for primary aldosteronism was historically recommended in patients with moderate to severe and/or resistant hypertension. Patients with mild hypertension and normotensive subjects were therefore excluded from the screening. However, a considerable number of normotensive individuals without hypokalaemia may have subclinical forms of primary ...
Yuji, Ito   +2 more
exaly   +3 more sources

Subclinical Primary Aldosteronism and Cardiovascular Health: A Population-Based Cohort Study

Circulation, 2023
BACKGROUND: Primary aldosteronism, characterized by overt renin-independent aldosterone production, is a common but underrecognized form of hypertension and cardiovascular disease.
G. Hundemer   +17 more
semanticscholar   +1 more source

Primary aldosteronism

Journal of Endocrinological Investigation, 1995
The basic clinical pathophysiology of primary aldosteronism (PAL) was described by Conn in terms of autonomous production of aldosterone, secondary suppression of renin and development of hypertension with hypokalaemic alkalosis. Conn recognised a normokalaemic form of the syndrome and suggested that it might masquerade as essential hypertension and be
W R, Litchfield, R G, Dluhy
openaire   +7 more sources

Primary Aldosteronism: A Pragmatic Approach to Diagnosis and Management.

Mayo Clinic proceedings, 2023
Primary aldosteronism is a prevalent but underdiagnosed cause of hypertension, contributing to increased cardiovascular and cerebrovascular events and end-organ damage independent of blood pressure.
P. Dogra, I. Bancos, W. Young
semanticscholar   +1 more source

Diagnosis and treatment of primary aldosteronism.

The Lancet Diabetes and Endocrinology, 2021
Primary aldosteronism is a common cause of secondary hypertension associated with excess cardiovascular morbidities. Primary aldosteronism is underdiagnosed because it does not have a specific, easily identifiable feature and clinicians can be poorly ...
M. Reincke   +5 more
semanticscholar   +1 more source

Primary aldosteronism

Journal of Surgical Oncology, 2009
AbstractPrimary aldosteronism is the most common form of secondary hypertension. Case detection is based on an abnormal plasma aldosterone:plasma renin activity ratio and the diagnosis must be confirmed with an aldosterone suppression test. Subtype differentiation should be performed using adrenal venous sampling.
openaire   +4 more sources

Primary aldosteronism

Current Cardiology Reports, 2007
Primary aldosteronism is one of the few potentially curable forms of hypertension. This article highlights recent advances in the pathophysiology, diagnosis, and treatment of this relatively common secondary form of hypertension. These topics include the recognition that this disorder is more prevalent than previously assumed, the identification of ...
Richard J, Auchus, Fiemu E, Nwariaku
openaire   +2 more sources

Primary aldosteronism

Trends in Cardiovascular Medicine, 2016
In 1955 Dr Jerome Conn first documented primary aldosteronism (PA). Since then, screening, diagnosis and treatment have developed, in the process both refining and complicating management. Currently, screening requires 4-6 weeks of lead-up, including major changes in antihypertensive therapy, followed by a blood draw for plasma aldosterone ...
openaire   +3 more sources

Outcomes after medical treatment for primary aldosteronism: an international consensus and analysis of treatment response in an international cohort.

The Lancet Diabetes and Endocrinology
BACKGROUND Primary aldosteronism can be treated medically but there is no standardised method to evaluate treatment outcomes. We aimed to develop criteria for assessing the outcomes of targeted medical treatment of primary aldosteronism, analyse outcomes
Jun Yang   +53 more
semanticscholar   +1 more source

Clinical Management of Primary Aldosteronism: An Update

HYPERTENSION
Despite carrying an excess risk of cardiovascular events, primary aldosteronism (PA) is a commonly overlooked secondary form of arterial hypertension. An increased awareness of its high prevalence and broader screening strategies are urgently needed to ...
G. Rossi   +4 more
semanticscholar   +1 more source

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