Results 41 to 50 of about 958,893 (281)
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
FEBS Letters, EarlyView.Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
Languages, 2022 This research study explores teacher and student perceptions to verify consequential validity and the potential washback effect of a locally developed university-level English language proficiency test which consists of reading and listening-to-writing ...
Asli Lidice Gokturk Saglam, Dina Tsagari
doaj +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Catch Up Learning Programme: Primary Teacher's Guide
, 2022 Teachers Guide produced by the Improving Gender Attitudes, Transition and Education Outcomes OU team and included as resources to support the Government's National Catch Up Learning Strategy.
Griffiths, Malcolm +2 more
core +5 more sources
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Nordic Journal of Studies in Educational PolicyThis study examines how teachers are positioned as both agents and subjects within the discursive field of digital transformation. As education reforms in Nordic countries prioritise digitalisation, teacher professionalism is mobilised to mediate ...
E. S. Bussesund
doaj +1 more source
FEBS Letters, EarlyView.Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
Education SciencesEfficacy beliefs influence individuals’ thinking and academic outcomes. Indeed, a growing body of literature has identified self-efficacy (SE) as a predictor of a range of favourable outcomes and a buffer against the likelihood of less desirable ones ...
Annette Hessen Bjerke
doaj +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Cogent EducationThis qualitative case study explores the preparedness of primary school teachers in Gweru Urban District, Zimbabwe, to engage in self-directed learning (SDL) for integrating information and communication technology (ICT) into teaching and learning ...
Jocyleen Karima, Lockias Chitanana
doaj +1 more source