Results 61 to 70 of about 6,609,208 (359)

The asthma diagnosis jigsaw puzzle: an adaptable teaching concept to facilitate the diagnosis of asthma in adults and children presenting to primary care

open access: yesnpj Primary Care Respiratory Medicine
The asthma diagnosis jigsaw puzzle is a clinical practice and teaching concept conceived in clinical practice and refined through an expert multidisciplinary consensus process by academics and clinicians with an interest in primary respiratory care.
D. Ryan   +11 more
doaj   +1 more source

Optimal primary care management of clinical osteoarthritis and joint pain in older people: a mixed-methods programme of systematic reviews, observational and qualitative studies, and randomised controlled trials

open access: yesProgramme Grants for Applied Research, 2018
Background: Osteoarthritis (OA) is the most common long-term condition managed in UK general practice. However, care is suboptimal despite evidence that primary care and community-based interventions can reduce OA pain and disability.
Elaine Hay   +24 more
doaj   +1 more source

Managing risk in cancer presentation, detection and referral: a qualitative study of primary care staff views [PDF]

open access: yes, 2014
Objectives In the UK, there have been a number of national initiatives to promote earlier detection and prompt referral of patients presenting to primary care with signs and symptoms of cancer.
Cook, Neil   +2 more
core   +1 more source

Purification tags markedly affect self‐aggregation of CPEB3

open access: yesFEBS Letters, EarlyView.
Although recombinant proteins are used to study protein aggregation in vitro, uncleaved tags can interfere with accurate interpretation. Our findings demonstrate that His₆‐GFP and His₁₂ tags significantly affect liquid droplet and amyloid fibril formation in the intrinsically disordered region (IDR) of mouse cytoplasmic polyadenylation element‐binding ...
Harunobu Saito   +6 more
wiley   +1 more source

Fidelity evaluation of the compared procedures for conducting the PVS-PREDIAPS implementation strategy to optimize diabetes prevention in primary care

open access: yesBMC Family Practice, 2021
Background Assessing the fidelity of an implementation strategy is important to understand why and how the strategy influences the uptake of evidence-based interventions.
Alvaro Sánchez   +13 more
doaj   +1 more source

Trends in sexually transmitted infections in general practice 1990-2000: population based study using data from the UK general practice research database [PDF]

open access: yes, 2006
Objective: To describe the contribution of primary care to the diagnosis and management of sexually transmitted infections in the United Kingdom, 1990-2000, in the context of increasing incidence of infections in genitourinary medicine clinics ...
Brook, M.G.   +13 more
core  

Palliative care in the community [PDF]

open access: yes, 2007
Primary care has a vital role in delivering palliative care. In most developed countries more people die in hospital than at home, although substantially more people would prefer to die at home.
Dale, Jeremy, Munday, Dan
core   +2 more sources

Circulating histones as clinical biomarkers in critically ill conditions

open access: yesFEBS Letters, EarlyView.
Circulating histones are emerging as promising biomarkers in critical illness due to their diagnostic, prognostic, and therapeutic potential. Detection methods such as ELISA and mass spectrometry provide reliable approaches for quantifying histone levels in plasma samples.
José Luis García‐Gimenez   +17 more
wiley   +1 more source

Coping with complexity: working beyond the guidelines for patients with multimorbidities [PDF]

open access: yes, 2015
Primary care physicians believe they are delivering evidence-based care, understanding that adherence to evidence-based clinical guidelines results in tangible benefits in the populations for which they were developed.
Treadwell, Julian
core   +3 more sources

Primary Care and Primary Care Training: Mirror Images [PDF]

open access: yesJournal of General Internal Medicine, 2010
Primary care appears to be in a perpetual state of crisis. The failures are well known. Primary care physicians work in stressful, under-resourced work environments with overcrowded schedules geared towards acute care. Chronic disease patients receive inadequate treatment and physicians lack the time, expertise and money to systematically measure and ...
Eric J. Warm, Emily L. Leasure
openaire   +3 more sources

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