Results 191 to 200 of about 100,000 (276)
Acta Physiologica, Volume 242, Issue 2, February 2026.ABSTRACT Aim Acyl‐CoA binding protein plays a vital role in lipid metabolism by mediating the intracellular flux and utilization of long‐chain acyl‐CoAs. We generated an adipocyte‐wide ACBP knockout mouse and a brown adipose tissue‐specific ACBP knockout mouse to investigate ACBP function in adipose tissue.
M. F. Nørremark +13 more
wiley +1 more source
Diabetes, Obesity and Metabolism, Volume 28, Issue 2, Page 826-839, February 2026.Abstract Maternally inherited diabetes and deafness (MIDD) is a mitochondrial disorder usually caused by the variant m.3243A>G in the MT‐TL1 gene. We have proposed that diabetes in MIDD arises from a combination of insulin resistance and impaired β‐cell function that is more likely to occur in the presence of high skeletal muscle heteroplasmy and ...
Ahsen Chaudhry +2 more
wiley +1 more source
Archives of Cardiovascular Diseases Supplements, 2022 B. Lefort +9 more
semanticscholar +1 more source
Diabetes, Obesity and Metabolism, Volume 28, Issue 2, Page 878-894, February 2026.Abstract Epicardial adipose tissue (EAT) is a metabolically active visceral fat depot located between the myocardium and the visceral pericardium, exerting direct paracrine and vasocrine effects on the heart and coronary vessels. Under physiological conditions, EAT supports myocardial energy metabolism and thermoregulation through fatty acid supply and
Elisabeth Heuboeck +2 more
wiley +1 more source
EAN 2024 Guideline on the Diagnostic Approach to Oligo/Asymptomatic HyperCKemia
European Journal of Neurology, Volume 33, Issue 2, February 2026.ABSTRACT Background Recent epidemiological studies on the general population reveal that up to 1.3% have oligo/asymptomatic hyperCKemia. Objective This guideline aims to provide updated, evidence‐based recommendations on investigating persons older than 18 years.
T. Kyriakides +15 more
wiley +1 more source
Tks4‐Targeted Gene Therapy Inhibited White Adipocyte Hypertrophy in Mice
The FASEB Journal, Volume 40, Issue 2, 31 January 2026.Tks4 knockout or knockdown by AAV mediated shRNA both successfully restricted adipocyte hypertrophy in high fat diet. The reduction of TAG was validated by biochemistry and lipidomics analyses. This study suggested a potential of Tks4 targeted therapy in obesity intervention. ABSTRACT Obesity is one of the most prevalent public health issues worldwide,
Meng Tian +5 more
wiley +1 more source
Biochemical and Physiological Effects of Galanin in Health and Disease
The FASEB Journal, Volume 40, Issue 2, 31 January 2026.Galanin is a biologically active neuropeptide hormone that mediates its effects through three galanin receptors. Galanin signaling induces changes in glucose homeostasis amongst others and plays a dynamic role in the physiological health of many organ systems.
Patrick Mireles +3 more
wiley +1 more source
The FASEB Journal, Volume 40, Issue 1, 15 January 2026.Proximal tubule‐specific PPARα knockout mouse (PPARαΔKPT) showed decreased lipid and glucose metabolism in the kidney during fasting. Metabolism in the other organs was increased, presumably as a means of compensating for the impaired kidney metabolism.
Daiki Aomura +12 more
wiley +1 more source
Primary carnitine deficiency in two sisters with intractable epilepsy and reversible metabolic cardiomyopathy: Two case reports. [PDF]
Exp Ther Med, 2020 Yang XF, Liu GS, Yi B.
europepmc +1 more source