Results 1 to 10 of about 69,736 (263)

Carnitine Inborn Errors of Metabolism

open access: yesMolecules, 2019
Carnitine plays essential roles in intermediary metabolism. In non-vegetarians, most of carnitine sources (~75%) are obtained from diet whereas endogenous synthesis accounts for around 25%.
Mohammed Almannai   +2 more
exaly   +3 more sources

Targeted Metabolomic Profiling of Carnitines Reveals Diagnostic Candidates in Postpartum Cardiomyopathy [PDF]

open access: yesMetabolites
Background: Postpartum cardiomyopathy (PPCM) is a rare but life-threatening condition characterized by left ventricular dysfunction occurring in the peripartum period.
Yasemin Behram Kandemir   +3 more
doaj   +2 more sources

The Metabolite Differences in Vascular Smooth Muscle Cells of Abdominal Aortic Aneurysm Revealed by Untargeted Metabolomics [PDF]

open access: yesBiomedicines
Background: Abdominal aortic aneurysm (AAA) is a vascular disease with a high mortality rate upon rupture (85–90%). Surgical repair remains the most effective intervention, whereas pharmacological treatments to prevent aneurysm expansion or rupture are ...
Yuqi Yi   +4 more
doaj   +2 more sources

Evaluation of the Effect of L-Carnitine Supplementation in Preterm Neonates Suffering from Respiratory Distress Syndrome [PDF]

open access: yesInternational Journal of Medical Arts, 2022
Background: Carnitine is one of hydrophilic amino acid derivatives participating in pulmonary surfactant production in infants. The deficiency of Carnitine might lead to the incidence and severity of respiratory distress syndrome [RDS] in preterm infants.
Safaa Beshir   +3 more
doaj   +1 more source

The Effects of L-Carnitine, Acetyl-L-Carnitine, and Propionyl-L-Carnitine on Body Mass in Type 2 Diabetes Mellitus Patients

open access: yesFrontiers in Nutrition, 2021
Purpose: The study aimed to explore the effects of l-carnitine, acetyl-l-carnitine, and propionyl-l-carnitine on Body Mass in type 2 diabetes mellitus (T2DM) patients.Methods: Randomized controlled trial (RCT) studies of l-carnitine, acetyl-l-carnitine ...
Dong-Dong Wang   +4 more
doaj   +1 more source

Successful treatment of propofol-related infusion syndrome in critically ill patient receiving low-dose propofol infusion: a case report [PDF]

open access: yesAcute and Critical Care, 2023
Propofol is widely used to sedate agitated patients in intensive care units. However, it can cause a rare but fatal complication, propofol-related infusion syndrome (PRIS).
Nahyeon Park, Tae Sun Ha
doaj   +1 more source

The Comparative Effect of L-carnitine in Different Stages of Pregnancy on Alcohol-induced Memory Impairment in Adult Rat Offspring [PDF]

open access: yesمجله دانشکده پزشکی اصفهان, 2022
Background: Neuroprotective effects of L-carnitine on damage caused by fetal exposure to ethanol have been demonstrated. The purpose of this study was to evaluate the effects of different doses of L-carnitine at different stages of pregnancy on the ...
Zahra Iranpour   +3 more
doaj   +1 more source

Stable isotope-labeled carnitine reveals its rapid transport into muscle cells and acetylation during contraction

open access: yesHeliyon, 2023
Carnitine plays multiple roles in skeletal muscle metabolism, including fatty acid transport and buffering of excess acetyl-CoA in the mitochondria. The skeletal muscle cannot synthesize carnitine; therefore, carnitine must be taken up from the blood ...
Yasuro Furuichi   +5 more
doaj   +1 more source

Clinical and molecular characteristics of carnitineacylcarnitine translocase deficiency with c.270delC and a novel c.408C>A variant

open access: yesThe Turkish Journal of Pediatrics, 2021
Background. Carnitine-acylcarnitine translocase deficiency (CACTD) is a rare, autosomal recessive, and highly lethal fatty acid oxidation (FAO) disorder caused by defective acylcarnitine transport across the mitochondrial membrane.
Berrak Bilginer Gürbüz   +7 more
doaj   +1 more source

Assessment of carnitine excretion and its ratio to plasma free carnitine as a biomarker for primary carnitine deficiency in newborns

open access: yesJIMD Reports, 2023
In the Netherlands, newborns are referred by the newborn screening (NBS) Program when a low free carnitine (C0) concentration (
Loek L. Crefcoeur   +4 more
doaj   +1 more source

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