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Evaluation of Carnitine Status in Postnatal Piglets from Sows Fed Clofibrate [PDF]

open access: yesCurrent Issues in Molecular Biology
Milk carnitine content decreases quickly with lactation days and is accompanied by PPARα downregulation. This study aimed to investigate the effects of the maternal supplementation of the PPARα agonist, clofibrate, on milk carnitine content and carnitine
Brandon Pike   +6 more
doaj   +2 more sources

Targeted Metabolomic Profiling of Carnitines Reveals Diagnostic Candidates in Postpartum Cardiomyopathy [PDF]

open access: yesMetabolites
Background: Postpartum cardiomyopathy (PPCM) is a rare but life-threatening condition characterized by left ventricular dysfunction occurring in the peripartum period.
Yasemin Behram Kandemir   +3 more
doaj   +2 more sources

The Metabolite Differences in Vascular Smooth Muscle Cells of Abdominal Aortic Aneurysm Revealed by Untargeted Metabolomics [PDF]

open access: yesBiomedicines
Background: Abdominal aortic aneurysm (AAA) is a vascular disease with a high mortality rate upon rupture (85–90%). Surgical repair remains the most effective intervention, whereas pharmacological treatments to prevent aneurysm expansion or rupture are ...
Yuqi Yi   +4 more
doaj   +2 more sources

Evaluation of the Effect of L-Carnitine Supplementation in Preterm Neonates Suffering from Respiratory Distress Syndrome [PDF]

open access: yesInternational Journal of Medical Arts, 2022
Background: Carnitine is one of hydrophilic amino acid derivatives participating in pulmonary surfactant production in infants. The deficiency of Carnitine might lead to the incidence and severity of respiratory distress syndrome [RDS] in preterm infants.
Safaa Beshir   +3 more
doaj   +1 more source

Metabolic Changes Precede the Development of Pulmonary Hypertension in the Monocrotaline Exposed Rat Lung. [PDF]

open access: yes, 2016
There is increasing interest in the potential for metabolic profiling to evaluate the progression of pulmonary hypertension (PH). However, a detailed analysis of the metabolic changes in lungs at the early stage of PH, characterized by increased ...
Black, Stephen M   +10 more
core   +20 more sources

The Effects of L-Carnitine, Acetyl-L-Carnitine, and Propionyl-L-Carnitine on Body Mass in Type 2 Diabetes Mellitus Patients

open access: yesFrontiers in Nutrition, 2021
Purpose: The study aimed to explore the effects of l-carnitine, acetyl-l-carnitine, and propionyl-l-carnitine on Body Mass in type 2 diabetes mellitus (T2DM) patients.Methods: Randomized controlled trial (RCT) studies of l-carnitine, acetyl-l-carnitine ...
Dong-Dong Wang   +4 more
doaj   +1 more source

Stable isotope-labeled carnitine reveals its rapid transport into muscle cells and acetylation during contraction

open access: yesHeliyon, 2023
Carnitine plays multiple roles in skeletal muscle metabolism, including fatty acid transport and buffering of excess acetyl-CoA in the mitochondria. The skeletal muscle cannot synthesize carnitine; therefore, carnitine must be taken up from the blood ...
Yasuro Furuichi   +5 more
doaj   +1 more source

Change in Anemia by Carnitine Supplementation in Patients Undergoing Peritoneal Dialysis: A Retrospective Observational Study

open access: yesFrontiers in Medicine, 2021
Background: Carnitine supplementation improves various dialysis-related symptoms including erythropoietin-resistant anemia in patients who are undergoing hemodialysis.
Shohei Kaneko   +6 more
doaj   +1 more source

Successful treatment of propofol-related infusion syndrome in critically ill patient receiving low-dose propofol infusion: a case report [PDF]

open access: yesAcute and Critical Care, 2023
Propofol is widely used to sedate agitated patients in intensive care units. However, it can cause a rare but fatal complication, propofol-related infusion syndrome (PRIS).
Nahyeon Park, Tae Sun Ha
doaj   +1 more source

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