Results 11 to 20 of about 69,736 (263)

Carnitine and Depression

open access: yesFrontiers in Nutrition, 2022
Depression has become one of the most common mental diseases in the world, but the understanding of its pathogenesis, diagnosis and treatments remains insufficient.
Ting Liu   +12 more
doaj   +3 more sources

Inulin-Based Polymeric Micelles Functionalized with Ocular Permeation Enhancers: Improvement of Dexamethasone Permeation/Penetration through Bovine Corneas

open access: yesPharmaceutics, 2021
Ophthalmic drug delivery is still a challenge due to the protective barriers of the eye. A common strategy to promote drug absorption is the use of ocular permeation enhancers, while an innovative approach is the use of polymeric micelles. In the present
Giulia Di Prima   +4 more
doaj   +1 more source

Detection of Early Onset Carnitine Palmitoyltransferase II Deficiency by Newborn Screening: Should CPT II Deficiency Be a Primary Disease Target?

open access: yesInternational Journal of Neonatal Screening, 2021
Early-onset carnitine palmitoyltransferase II deficiency (CPT II deficiency) (OMIM 600650) can result in severe outcomes, which are often fatal in the neonatal to infantile period.
Rachel Mador-House   +2 more
doaj   +1 more source

Serum metabolic alterations in peritoneal dialysis patients with excessive daytime sleepiness

open access: yesRenal Failure, 2023
Excessive daytime sleepiness (EDS) is associated with quality of life and all-cause mortality in the end-stage renal disease population. This study aims to identify biomarkers and reveal the underlying mechanisms of EDS in peritoneal dialysis (PD ...
Wei Chen   +8 more
doaj   +1 more source

Multicohort Metabolomics Analysis Discloses 9‐Decenoylcarnitine to Be Associated With Incident Atrial Fibrillation

open access: yesJournal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2021
Background The molecular mechanisms involved in atrial fibrillation are not well known. We used plasma metabolomics to investigate if we could identify novel biomarkers and pathophysiological pathways of incident atrial fibrillation.
Lars Lind   +7 more
doaj   +1 more source

Valproic-induced Fanconi syndrome: Clinical features, risk factors, diagnosis and management

open access: yesFrontiers in Medicine, 2022
ObjectiveAlthough Fanconi syndrome (FS) induced by valproate (VPA) has occasionally been reported, the detailed clinical features of the disease remain unclear.
Chunjiang Wang   +4 more
doaj   +1 more source

The pathophysiology of leg cramping during dialysis and the use of carnitine in its treatment

open access: yesPhysiological Reports, 2021
Leg cramping is a common side effect of hemodialysis, and this is frequently treated by the administration of carnitine, but this is not effective in every patient. Alkalosis is a key component of the etiology of leg cramping during hemodialysis sessions.
Akira Takahashi
doaj   +1 more source

The Effects of Streptozotocin-Induced Diabetes and Insulin Treatment on Carnitine Biosynthesis and Renal Excretion

open access: yesMolecules, 2021
Carnitine insufficiency is reported in type 1 diabetes mellitus. To determine whether this is accompanied by defects in biosynthesis and/or renal uptake, liver and kidney were obtained from male Sprague-Dawley rats with streptozotocin-induced diabetes ...
Aman Upadhyay   +2 more
doaj   +1 more source

l-carnitine in critically ill patients—a case series study

open access: yesRenal Replacement Therapy, 2018
Background l-carnitine is essential for lipid metabolism, and lack of l-carnitine intake and loss by treatments lead to carnitine depletion causing muscle weakness, anemia, and immune dysfunction.
Takehiko Oami   +6 more
doaj   +1 more source

Effect of Supplementation of Diets with L-Carnitine and Methionin on Broiler Chicken Productive Performance [PDF]

open access: yesArchives of Razi Institute, 2023
The poultry industry is one of the pillars of food security in the world, as it is relied upon to provide meat and eggs to meet the increasing food demands.
A Mohammed Awad
doaj   +1 more source

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