Results 211 to 220 of about 33,228 (280)

Biallelic TMEM126B Variants as a Novel Cause of Kidney Failure—Implications for Mitochondrial Genetic Testing in Nephrology

Clinical Genetics, Volume 109, Issue 1, Page 206-208, January 2026.
An adult with kidney failure had compound‐heterozygous TMEM126B variants causing mitochondrial complex I deficiency. This expands TMEM126B to mitochondrial nephropathy and supports including mitochondrial genes in renal genetic testing.
Zachary T. Sentell, Anthony C. T. Cheung, Felicia Russo, Chantal Bernard, Rita Suri, Andrey V. Cybulsky, Daniela Buhas, Thomas M. Kitzler   +7 more
wiley   +1 more source

Endothelial cell CD36 optimizes tissue fatty acid uptake [PDF]

, 2018
Abumrad, Nada A, et al,, Peche, Vivek S, Pietka, Terri A, Samovski, Dmitri, Shoghi, Kooresh I   +5 more
core   +1 more source

Trained Immunity and Cardiovascular Risk: An Immunological Perspective

Immunological Reviews, Volume 337, Issue 1, January 2026.
ABSTRACT Systemic inflammation is a key driver of atherogenesis and its complications. While anti‐inflammatory therapies targeting pathways such as IL‐1β and IL‐6 have shown promise in established atherosclerotic cardiovascular disease (ASCVD), potential systemic effects raise concerns about immune suppression and infection, underscoring the need for ...
Katherine A. Boden, Jason Chai, Tafadzwa T. J. Kufazvinei, Robin P. Choudhury   +3 more
wiley   +1 more source

Combining thiopurine with partial enteral nutrition promotes complete mucosal healing in pediatric Crohn's disease

Pediatrics International, Volume 68, Issue 1, January/December 2026.
Abstract Background The combination of thiopurines and partial enteral nutrition (TP/PEN) is a common maintenance therapy for mild‐to‐moderate Crohn's disease (CD) in pediatric patients. However, no studies have investigated the efficacy of TP/PEN. This study aimed to evaluate the non‐relapse and complete mucosal healing rates in pediatric CD patients ...
Emiri Kaji, Atsushi Yoden, Takahiro Namba, Satomi Nishimoto, Masano Otani, Takeru Okuhira, Keisuke Inoue, Tomoki Aomatsu, Daisuke Nishioka, Akira Ashida   +9 more
wiley   +1 more source

The Role of Innate Lymphoid Cells in the Pathogenesis of Hepatic Echinococcosis: A Literature Review

Parasite Immunology, Volume 48, Issue 1, January 2026.
ABSTRACT Hepatic echinococcosis (HE), a major zoonotic disease, remains endemic in pastoral regions of Western China, where its incidence is closely linked to geographical, livestock and sanitary conditions. The disease presents a significant clinical challenge due to the complexity of host–parasite interactions and a high recurrence rate. To date, the
Wei Ma, Dian Wang, Chuanchuan Liu, Haining Fan   +3 more
wiley   +1 more source

Stress Nutrition in Aquatic Animals: From Definition to Practice

Reviews in Aquaculture, Volume 18, Issue 1, January 2026.
ABSTRACT Aquaculture faces numerous challenges, with stress being one of the major issues that lead to growth loss, metabolic disorders, weakened immunity, redox imbalance, and organ damage in aquatic animals. Nutritional intervention is one of the effective strategies to address these problems. Traditional research has primarily focused on the impacts
Jian Zhang, Qianwen Ding, Ruobing Lou, Yuanpei Zhang, Yuanyuan Yao, Yalin Yang, Zhen Zhang, Chao Ran, Zhigang Zhou   +8 more
wiley   +1 more source

The multifaceted roles of ketones in physiology

Experimental Physiology, Volume 111, Issue 1, Page 1-13, 1 January 2026.
Abstract The production of ketones, referred to as ketogenesis, plays an essential role in maintaining energy homeostasis during prolonged fasting/starvation, which primarily stems from its ability to serve as a fuel source to support neuronal ATP production, thereby limiting muscle wasting. Over the years, the field has come to appreciate that ketones
Seyed Amirhossein Tabatabaei Dakhili, Kunyan Yang, Magnus J. Stenlund, John R. Ussher   +3 more
wiley   +1 more source

Effects of short‐term exercise on plasma metabolic and lipidomic profiles of individuals with type 2 diabetes

Experimental Physiology, Volume 111, Issue 1, Page 69-97, 1 January 2026.
Abstract Type 2 diabetes mellitus (T2DM) is a common metabolic disorder characterized by chronic hyperglycaemia, with physical inactivity and excessive adiposity as predisposing factors. This clinical trial aimed to investigate the effects of an exercise intervention on the metabolome of T2DM participants, fasting and in response to an oral glucose ...
Maartje Cox, Aaron Raman, Timothy Fairchild, John P. Beilby, Bu B. Yeap, Jeremy K. Nicholson, Julien Wist, Jeremiah Peiffer, Nathan G. Lawler   +8 more
wiley   +1 more source

Bioenergetic profiles and respiratory control in mitochondrial physiology: Precision analysis of oxidative phosphorylation

Experimental Physiology, Volume 111, Issue 1, Page 179-211, 1 January 2026.
Abstract Oxidative phosphorylation (OXPHOS) is fundamental to mitochondrial function. Respirometry with living cells provides limited information compared to precision OXPHOS analysis with mitochondrial preparations, including isolated mitochondria, tissue homogenates, permeabilized tissues, and permeabilized cells.
Alba Timón‐Gómez, Carolina Doerrier, Zuzana Sumbalová, Luiz F. Garcia‐Souza, Eleonora Baglivo, Luiza H. D. Cardoso, Erich Gnaiger   +6 more
wiley   +1 more source

Insulin stimulated upregulation of OCTN2 carnitine transporters is impaired in patients with Primary carnitine deficiency [PDF]

R Dahl, Tórur Sjúrðarson, Poula Patursson, Arthur Ingersen, Peter Andersen, Johannes Ravn Jørgensen, Elizabeth J. Simpson, Jan Rasmussen, Kasper Kyhl, Paul L. Greenhaff, Flemming Dela, Steen Larsen, Clara Prats   +12 more
openalex   +1 more source