Results 61 to 70 of about 100,000 (276)

Effect of Combined Oral Ferrotherapy with L-carnitine on Exercise Tolerance of Patients with Chronic Heart Failure with Reduced Ejection Fraction of Left Ventricle with Concomitant Iron Deficiency Anemia [PDF]

, 2019
According to numerous studies, a high prevalence of iron deficiency (ID) with anaemic syndrome and its association with mortality during chronic heart failure (CHF) have been revealed.
Ivanov, V. (Valerii), Kolesnyk, М. (Маriia)   +1 more
core   +3 more sources

Primary Carnitine Deficiency: Rare Cause of Paediatric Dilated Cardiomyopathy, Often Underdiagnosed

Scholars Journal of Medical Case Reports, 2023
Primary carnitine deficiency (PCD) is an autosomal recessive disorder of fatty acid beta-oxidation. Which results from a defect in the transport of carnitine and is one of the rare treatable etiologies of metabolic cardiomyopathies. Affected patients may
I. Filali, I. Hmimidi, H. Aouraghe, A. Bentahila   +3 more
semanticscholar   +1 more source

Potential therapeutic use of the ketogenic diet in autism spectrum disorders. [PDF]

, 2014
The ketogenic diet (KGD) has been recognized as an effective treatment for individuals with glucose transporter 1 (GLUT1) and pyruvate dehydrogenase (PDH) deficiencies as well as with epilepsy.
Dueñas, Nadia, Giulivi, Cecilia, Napoli, Eleonora   +2 more
core   +1 more source

Dysregulated Choline, Methionine, and Aromatic Amino Acid Metabolism in Patients with Wilson Disease: Exploratory Metabolomic Profiling and Implications for Hepatic and Neurologic Phenotypes. [PDF]

, 2019
Wilson disease (WD) is a genetic copper overload condition characterized by hepatic and neuropsychiatric symptoms with a not well-understood pathogenesis.
Czlonkowska, Anna, Kim, Kyoungmi, Litwin, Tomasz, Mazi, Tagreed A, Medici, Valentina, Sarode, Gaurav V, Shibata, Noreene M   +6 more
core   +2 more sources

Regulation of genes involved in carnitine homeostasis by PPARa across different species (rat, mouse, pig, cattle, chicken, and human) [PDF]

, 2012
Recent studies in rodents convincingly demonstrated that PPAR-alpha is a key regulator of genes involved in carnitine homeostasis, which serves as a reasonable explanation for the phenomenon that energy deprivation and fibrate treatment, both of which ...
Egeri, Leonie, Forkmann, Thomas, Gläsmer, Heide, Margraf, Jürgen, Teismann, Tobias   +4 more
core   +1 more source

Essential lipid autacoids rewire mitochondrial energy efficiency in metabolic dysfunction‐associated fatty liver disease

Hepatology, EarlyView., 2022
Increased liver content of DHA‐derived small lipid autacoids (i.e resolvin D1 and maresin 1) associates with enhanced mitochondrial oxidative phosphorylation, fatty acid β‐oxidation and bioenergetic metabolic flux. These features provide hepatic protection from steatotic, pro‐inflammatory and fibrogenic insults.
Cristina López‐Vicario, David Sebastián, Mireia Casulleras, Marta Duran‐Güell, Roger Flores‐Costa, Ferran Aguilar, Juan José Lozano, Ingrid W. Zhang, Esther Titos, Jing X. Kang, Antonio Zorzano, Makoto Arita, Joan Clària   +12 more
wiley   +1 more source

Twin Brothers with Carnitine Membrane Transporter Deficiency: A Case Study

Advanced Biomedical Research, 2018
Carnitine membrane transporter deficiency or primary carnitine deficiency (PCD) is an autosomal recessive disorder of fatty acid oxidation, in which the transport of carnitine into cells is impaired.
Elham Hashemi Dehkordi, Payam Sobhani, Nabiolah Asadpour, Mahin Hashemipour, Neda Mostofizadeh   +4 more
doaj   +1 more source

Special topic: The association between pulse ingredients and canine dilated cardiomyopathy: addressing the knowledge gaps before establishing causation. [PDF]

, 2019
In July 2018, the Food and Drug Administration warned about a possible relationship between dilated cardiomyopathy (DCM) in dogs and the consumption of dog food formulated with potatoes and pulse ingredients.
Adin, Alroy, Anna K Shoveller, Arslan, Avilés-Gaxiola, Backus, Baker, Baker, Bakker, Borgarelli, Butterwick, Bélanger, Cattanach, Christopher P F Marinangeli, Columbus, Daniel A Columbus, de Godoy, Degen, Dodd, Dutton, Fascetti, Flanagan, Freeman, Freeman, Freeman, Gloaguen, Greg Aldrich, Haber, Homann, Hoppel, Hou, Hurrell, Huxtable, Ito, Jennifer A Larsen, Johnson, Johnson, Kaplan, Kari J Ekenstedt, Keene, Kim, Kim, Kittleson, Ko, Kramer, Lien, Linder, Lynn Weber, Mansilla, Marinangeli, Maron, Marshall, Martin, Mathai, Menniti, Merheb, Meurs, Meurs, Moehn, Moise, Monnet, Nardelli, Nyachoti, Owczarek-Lipska, O’Máille, Patterson, Pion, Pion, Rice, Roberfroid, Robinson, Robinson, Răşanu, Sanderson, Sarah K Abood, Schaffer, Sisson, Spitze, Stoll, Story, Swanson, Teodorowicz, Tosh, Tôrres, Werner, Wilfredo D Mansilla, Worden, Yamka, Žilić   +88 more
core   +1 more source

Primary Carnitine Deficiency as a Treatable Cause of Heart Failure in Young Patients.

Turk Kardiyoloji Dernegi arsivi : Turk Kardiyoloji Derneginin yayin organidir, 2022
Non-ischemic dilated cardiomyopathy is the most common subgroup of heart failure in young adults. Several metabolic defects could be the underlying etiology in these young heart failure patients. However, most cases are considered idiopathic.
M. Kayıkçıoğlu, Benay Özbay, B. Yağmur, E. Canda, S. Bayraktaroğlu, E. Şimşek, S. Kalkan Uçar   +6 more
semanticscholar   +1 more source

The NADPH oxidase NOX4 regulates redox and metabolic homeostasis preventing HCC progression

Hepatology, EarlyView., 2022
Loss of NOX4 in HCC tumor cells induces metabolic reprogramming in a Nrf2/MYC‐dependent manner to promote HCC progression. Abstract Background and Aims The NADPH oxidase NOX4 plays a tumor‐suppressor function in HCC. Silencing NOX4 confers higher proliferative and migratory capacity to HCC cells and increases their in vivo tumorigenic potential in ...
Irene Peñuelas‐Haro, Rut Espinosa‐Sotelo, Eva Crosas‐Molist, Macarena Herranz‐Itúrbide, Daniel Caballero‐Díaz, Ania Alay, Xavier Solé, Emilio Ramos, Teresa Serrano, María L. Martínez‐Chantar, Ulla G. Knaus, José M. Cuezva, Antonio Zorzano, Esther Bertran, Isabel Fabregat   +14 more
wiley   +1 more source