Results 301 to 310 of about 5,628,138 (356)

Keeping pace: the primary cilium as the conducting baton of the islet. [PDF]

Diabetologia
Idevall-Hagren O, Incedal Nilsson C, Sanchez G.   +2 more
europepmc   +1 more source

Dynamic changes in ultrastructure of the primary cilium in migrating neuroblasts in the postnatal brain(生後脳内を移動する新生ニューロンにおける一次繊毛の微細構造の動的変化)<内容の要旨及び審査結果の要旨>

, 2020
真実 松本
openalex   +1 more source

A highly abundant circular RNA from the RMST locus plays a role in posterior fossa ependymoma pathogenesis

Brain Pathology, EarlyView.
circRMST (hsa_circ_0099634) is by far the most abundant isoform from the RMST locus. It is highly expressed in cancer cells throughout ependymoma patient samples and is located in the cytoplasm. circRMST knockdown causes cell cycle arrest and induces differentiation, and it is a marker for poor prognosis. The figure is made using BioRender.
Ulvi Ahmadov, Charlotte W. Udengaard, Stine M. Vissing, Silke D. Nielsen, Kim‐Gwendolyn Dietrich, Benedicte Parm Ulhøi, Lasse S. Kristensen   +6 more
wiley   +1 more source

Optic nerve sheath meningioma exhibits neural niche‐associated transcriptomic features and rare copy number variation‐linked evolution

Brain Pathology, EarlyView.
Optic nerve sheath meningiomas are typically NF2‐intact with few copy number alterations and are generally clinically indolent. Rare aggressive recurrences are associated with progressive accumulation of copy number variations, including CDKN2A/B homozygous deletion, 1q gain, and 14q loss.
Daisuke Sato, Satoru Miyawaki, Yu Sakai, Kenta Ohara, Yu Teranishi, Yudai Hirano, Motoyuki Umekawa, Takahiro Tsuchiya, Shotaro Ogawa, So Hirata, Hiroki Hongo, Hideaki Ono, Daisuke Komura, Tetsuo Ushiku, Shumpei Ishikawa, Nobuhito Saito   +15 more
wiley   +1 more source

The potential for biased signalling in the P2Y receptor family of GPCRs

British Journal of Pharmacology, EarlyView.
The purinergic receptor family is primarily activated by nucleotides, and contains members of both the G protein coupled‐receptor (GPCR) superfamily (P1 and P2Y) and ligand‐gated ion channels (P2X). The P2Y receptors are widely expressed in the human body, and given the ubiquitous nature of nucleotides, purinergic signalling is involved with a plethora
Claudia M. Sisk, Simon Pitchford, Graham Ladds   +2 more
wiley   +1 more source

Peritumoral Clefts in Basal Cell Carcinoma: Matrix Metabolism and Primary Cilium. [PDF]

Cureus
Martínez-Ortega JI.
europepmc   +1 more source

Financially Coerced ‘Self‐Produced’ Child Sexual Exploitation Material: Narratives of Accountability

Child &Family Social Work, EarlyView.
ABSTRACT Perpetrators financially coerce children to ‘self‐produce’ child sexual exploitation material (CSEM). A harmful dominant narrative has historically blamed victims by framing this form of child sexual exploitation as ‘children engaging in sex work’ obfuscating the tactics of perpetrators.
Genevieve Bloxsom, Gemma McKibbin, Jennifer Davidson, Nick Halfpenny, Cathy Humphreys   +4 more
wiley   +1 more source

Astrocyte-Specific Inhibition of the Primary Cilium Suppresses C3 Expression in Reactive Astrocyte. [PDF]

Cell Mol Neurobiol
Muhamad NA, Masutani K, Furukawa S, Yuri S, Toriyama M, Matsumoto C, Itoh S, Shinagawa Y, Isotani A, Toriyama M, Itoh H.   +10 more
europepmc   +1 more source

Expanding the Phenotypic Spectrum Associated With Loss‐of‐Function SMARCA4 Variants to Eye Developmental Anomalies

Clinical Genetics, EarlyView.
This study expands the clinical spectrum of SMARCA4 by describing a novel phenotype in three unrelated individuals with truncating variants. Distinct from Coffin–Siris syndrome and rhabdoid tumor predisposition, this new association is characterized by ocular malformations, specifically microphthalmia and coloboma.
Bertrand Chesneau, Marjolaine Willems, Abdelhakim Bouazzaoui, Léopoldine Lequeux, Julie Plaisancié, Salima El Chehadeh, Hélène Dollfus, Nicolas Chassaing   +7 more
wiley   +1 more source

Role of lipids in the control of autophagy and primary cilium signaling in neurons. [PDF]

Neural Regen Res
Hernández-Cáceres MP, Pinto-Nuñez D, Rivera P, Burgos P, Díaz-Castro F, Criollo A, Yañez MJ, Morselli E.   +7 more
europepmc   +1 more source