Results 51 to 60 of about 5,069,987 (201)

Navigating the Complexity: A Comprehensive Review of GSK‐3 Inhibition in Regenerative Medicine

Medicinal Research Reviews, EarlyView.
ABSTRACT Glycogen synthase kinase‐3 (GSK‐3) is a central regulator of numerous cellular signaling pathways, with critical roles in metabolism, proliferation, differentiation, and tissue regeneration. This review explores the multifaceted effects of pharmacological GSK‐3 inhibition across multiple body districts, focusing on its highly context‐dependent
Davide Schiroli, Alessia Merra, Chiara Marraccini, Lucia Merolle, Graziella Pellegrini, Eleonora Maurizi   +5 more
wiley   +1 more source

International Study of Childhood Glaucoma

, 2020
To ascertain the types of childhood glaucoma managed at major international centers, current clinical practice, and intraocular pressure (IOP) control and visual acuity (VA) outcomes. Prospective, multicenter, consecutive case series.
International Study of Childhood Glaucoma – Childhood Glaucoma Research Network Study Group, Papadopoulos, Maria, Vanner, Elizabeth A, Grajewski, Alana L   +3 more
core   +1 more source

Optimal Resources for Children's Surgery 2: Tiered Recommendations for Minimum Essential Children's Surgical Procedures Across Health System Levels

World Journal of Surgery, EarlyView.
In 2015 the World Health Assembly (WHO), based on recommendations by the Lancet Commission on Global Surgery, passed resolution (68:15) on strengthening emergency and essential surgical care and anesthesia as a component of universal health coverage. However, children's surgery was not adequately represented and in response, the Global Initiative for ...
Arpita Biswangree, Emmanuel A. Ameh, Kokila Lakhoo, Mohamed Shalaby, Sarah Beth Cairo, on behalf of GICS Membership, Abdelhafeez Hafeez, Dayang A Abdul Aziz, Abdur‐Rahman Lukman Olajide, Simone Abib, Mohammed J. Aboud, Abu Bakr Abdullah Adam Amal, Maimuna Abubakar, Piero Ali Alberti, Abdelbasit Elsayed, Abdullah Mohd Yusof, Abellar Hilda, Acharya Utsav, Amaraegbulam Peace Ifeoma, Amde Samuel Negash, Antoine Seraphin Gbenou, Arca Marjorie, Axt Jason, Banu Tahmina, Bezuhly Michael, Biswangree Arpita, Marilyn W. Butler, Michael Buzuhly, Sarah B. Cairo, Juan Francisco Campos Rodezno, Maija Cheung, Chirdan Lohfa, Milind Chitnis, Zachary Clapp, Hannah Cockrell, Aline Coltro, Deshpande Gaurav, Diao Mei, Donou Amivi Alice, Beda Espineda, Faye M. Evans, Ewnte Biniam, Fadhili Bake Jacques, Faktor Kara, Farmer Diana Lee, Gaffar Ilijana, Ganey Michael, Gathuya Zipporah, J. F. Gonzalez‐Zamora, Christa N. Grant, Gray Rebecca Crane, Hasnaien Ahmed, Hettiarachchi Mathula, Hsu Phillip, Ibrahim Rahma Wala Mohammed, Romeo C. Ignacio, Inglin Sophie, Islam Saleem, Kageni Maina Reuel, Kengo Nathan Ezie, Kisa Phyllis, Lakhoo Kokila, Langer Monica, Leodoro Basil, Lindert Judith, Lobos Pablo Andrés, Løfberg Katrine, Madhuri Vrisha, Martin Yturralde Erick, Mazingi Dennis, Mcleod Elizabeth Jane, John G. Meara, Felicity Vidya Mehendale, Felicity Vidya Mehendale, Milano Leecarlo, Hanifah N. A. Mohd, Moreno Amabelle, Mpongo Yves, Mrutu Salehe, Muthumani Abirami, Nah Shireen Anne, Naik‐Mathuria Bindi, Nandi Biplab, Ramesh M. Nataraja, Newton Odongo Charles, Nimanya Stella Alice, Nixon Cathrine, Ntegerejuwampaye Angélique, Obi Nkeiruka, Obisesan Aderonke Omoyeni, Odera Agneta, Ondima Lucienne Irene Patricia, Maryrose O. Osazuma, Owusu Ofori Emmanuel, Ozgediz Doruk, Pacheco Cesar Hector Alberto, Patel Nirav, Peer Shazia, Phelps Janey, Pilkington Mercedes, Poenaru Dan, Ravindran Vinitha, Rolle Udo, Saldaña Gallo Lily, Saleh Abdullah, Samad Lubna, Sedano Sabrina, Sethi Bijaya Kumar, Justina Seyi‐Olajide, Shalaby Mohamed Sameh, Sharma Mehek, Siddiqui Sabina, Stephens Caroline, Stoltz Judith, Talat Nabila, Warwick J. Teague, Tekant Gonca, Tumba Kapaso Nadyn, Wildhaber Barbara, Ava C. Yap, Zanon Nelci, Zope Madhushree   +121 more
wiley   +1 more source

Primary congenital glaucoma: An updated review

Saudi Journal of Ophthalmology, 2019
Primary congenital glaucoma (PCG) is a rare disease affecting children early in life. PCG was considered untreatable with inevitable blindness. However, recent advances in biochemical and genetic studies, the introduction of new diagnostic tools, intraocular pressure (IOP) lowering medications and improvement of surgical techniques have led to a better
Badawi, Abdulrahman H., Al-Muhaylib, Ahmed A., Al Owaifeer, Adi Mohammed, Al-Essa, Rakan S., Al-Shahwan, Sami A.   +4 more
openaire   +2 more sources

Clinical outcomes of the PAUL® glaucoma implant for secondary glaucoma

Acta Ophthalmologica, EarlyView.
Abstract Purpose Secondary glaucoma encompasses a broad spectrum of disease entities arising from diverse ocular pathologies and is often refractory to conventional treatment. Glaucoma drainage devices (GDDs) have therefore become an important surgical option.
Carolin Deubel, Benjamin Aretz, Wolfgang Walz, Michael Petrak, Frank G. Holz, Raffael Liegl, Karl Mercieca, Constance Liegl   +7 more
wiley   +1 more source

A cohort study of duplex Doppler examinations of the carotid artery in primary open angle glaucoma [PDF]

, 2014
Objectives To explore the possibility of pathological change in the common carotid artery at the bifurcation and in the internal carotid artery beyond the bifurcation which could contribute to a reduced diastolic pressure as observed in primary open ...
Aldoori, M. I., Marmion, Vincent J, Stephenson, John, Woodcock, J. P., Aldoori, Munther I, Woodcock, John P, Marmion, V. J., Stephenson, John; id_orcid   +7 more
core   +1 more source

Clinical and demographic profile of patients less than 40 years of age presenting to glaucoma services at a tertiary care eye hospital in South India

Indian Journal of Ophthalmology, 2022
Purpose: To study the clinical and demographic profile of patients less than 40 years of age presenting to glaucoma services including the reasons for referral.
Aditi Parab, Srinivasan Kavitha, Annamalai Odayappan, Rengaraj Venkatesh   +3 more
doaj   +1 more source

Trends in glaucoma diagnosis and medical management in Germany: A nationwide claims data analysis over 10 years

Acta Ophthalmologica, EarlyView.
Abstract Purpose Analysing longitudinal trends in recorded diagnosis and medical management of glaucoma in Germany over a 10‐year period. Methods A retrospective cohort study using nationwide outpatient claims and prescription data from the German statutory health insurance system.
Somar M. Hasan, Leonore Bovy, Maike Below, Kerstin Klimke, Alexander K. Schuster, Jan Darius Unterlauft, Carl Erb, Argyrios Chronopoulos, Robert P. Finger   +8 more
wiley   +1 more source

Inborn errors of immunity in children with neuroinflammation

Developmental Medicine &Child Neurology, EarlyView.
Abstract Inborn errors of immunity (IEIs), an expanding group of monogenic disorders with diverse clinical manifestations, are increasingly recognized to include neuroinflammatory disease. Examples of diseases included under this umbrella are Aicardi–Goutières syndrome, deficiency of adenosine deaminase 2, familial haemophagocytic lymphohistiocytosis ...
Eppie M Yiu, Dilan Dissanayake, Jessie Cunningham, Helen Branson, Ori Scott, E Ann Yeh   +5 more
wiley   +1 more source

Caregiver Burden in Primary Congenital Glaucoma

American Journal of Ophthalmology, 2019
To evaluate the demographic, clinical, and socioeconomic factors associated with variation in the quality of life (QOL) in caregivers of children with primary congenital glaucoma (PCG) in south India.Cross-sectional survey.Caregivers of children younger than 18 with diagnosed PCG were prospectively enrolled at Aravind Eye Hospital in Madurai and ...
Aditi, Kantipuly, Manju R, Pillai, Sujani, Shroff, Rakhee, Khatiwala, Ganesh V, Raman, S R, Krishnadas, Alan, Lee Robin, Joshua R, Ehrlich   +7 more
openaire   +3 more sources