Results 51 to 60 of about 34,204 (221)

The activation of KSHV lytic cycle blocks autophagy in PEL cells [PDF]

, 2015
This study confirms that autophagy is activated concomitantly with KSHV lytic cycle induction, and that autophagy inhibition by BECN1 knockdown reduces viral lytic gene expression.
CIRONE, Mara, FAGGIONI, Alberto, FARINA, Antonella, Filardi, M, GONNELLA, ROBERTA, GRANATO, Marisa, SANTARELLI, Roberta, TORRISI, Maria Rosaria   +7 more
core   +1 more source

Primary effusion lymphoma with skin involvement [PDF]

Journal of Clinical Pathology, 2006
Primary effusion lymphoma (PEL) was once defined as a body cavity-based lymphoma without identifiable contiguous tumour mass, but is now recognised as an independent clinicopathological entity. The case of a 67-year-old Japanese woman with PEL is reported, in which the clinical findings showed a pericardial effusion and multiple erythema on the ...
S, Inoue, T, Miyamoto, T, Yoshino, I, Yamadori, Y, Hagari, O, Yamamoto   +5 more
openaire   +2 more sources

Primary effusion lymphoma associated with Human Herpes Virus-8 and Epstein Barr virus in an HIV-infected woman from Kampala, Uganda: a case report

Journal of Medical Case Reports, 2011
Introduction Primary effusion lymphoma is a recently recognized entity of AIDS related non-Hodgkin lymphomas. Despite Africa being greatly affected by the HIV/AIDS pandemic, an extensive MEDLINE/PubMed search failed to find any report of primary effusion
Osuwat Lawrence O, Piccaluga Pier, Orem Jackson, Luzige Simon, Agostinelli Claudio, Lalitha Rejani, Tumwine Lynnette K, Pileri Stefano A   +7 more
doaj   +1 more source

‘Discovering’ primary effusion lymphoma in Malawi [PDF]

AIDS, 2018
Primary effusion lymphoma (PEL) is a rare non-Hodgkin lymphoma (NHL) associated with human herpesvirus 8 (HHV8) and increased incidence among HIV-positive individuals. PEL rarely presents as solid tumor masses, or extracavitary PEL (EPEL). We found one case of PEL and no EPEL reported from sub-Saharan Africa (SSA), despite high prevalence of HIV and ...
Montgomery, Nathan D, Gopal, Satish, Dhungel, Bal Mukunda, Zuze, Takondwa, Krysiak, Robert, Kaimila, Bongani, Randall, Cara, Kampani, Coxcilly, Tomoka, Tamiwe, Kasonkanji, Edwards, Seguin, Ryan, Painschab, Matthew S, Chimzimu, Fred, Fedoriw, Yuri, Mulenga, Maurice   +14 more
openaire   +1 more source

Rare case of primary extranodal marginal zone lymphoma of the thorax

Respiratory Medicine Case Reports, 2019
Primary lymphoma presenting a solitary lesion of the chest wall is extremely rare, as the majority of chest-wall tumors arise from metastasis. We report a case of a 64-year-old man with no history of HIV infection or pyothorax who presented with dry ...
Ahmed Ben Saad, Nesrine Fahem, Rim Khemakhem, Nouha Ben Abdeljelil, Asma Migaou, Manel Njima, Saousen Cheikh Mhamed, Samah Joobeur, Naceur Rouatbi   +8 more
doaj   +1 more source

Gastric cancer is the leading cause of death in Italian adult patients with common variable immunodeficiency [PDF]

, 2018
An increased prevalence of malignant lymphoma and of gastric cancer has been observed in large cohorts of patients with common variable immunodeficiency (CVID), the most frequently symptomatic primary immunodeficiency. Surveillance strategies for cancers
Agostini, Carlo, Cinetto, Francesco, Crescenzi, Ludovica, Milito, Cinzia, Pecoraro, Antonio, Pulvirenti, Federica, Quinti, Isabella, Rizzo, Francesca, Santangeli, Enrico, Spadaro, Giuseppe, Tabolli, Stefano, Valente, Michele   +11 more
core   +3 more sources

Histological Examination in Obtaining a Diagnosis in Patients with Lymphadenopathy in Lima, Peru. [PDF]

, 2017
The differential diagnosis for lymphadenopathy is wide and clinical presentations overlap, making obtaining an accurate diagnosis challenging. We sought to characterize the clinical and radiological characteristics, histological findings, and diagnoses ...
Abba, Al Kadah, Albasri, Carlton A. Evans, Cesar Ugarte-Gil, Chau, Daniela E. Kirwan, David A. J. Moore, de Noronha, Eduardo D. Matos, Eduardo Ticona, Eza, Gustavo Cerrillo, Hansen, Jaime Cok, Jon S. Friedland, José Luis Cabrera, Kirwan, Landis, Lawn, Moore, Moore, Muller, Ojo, Olu-Eddo, Olu-Eddo, Ondounda, Osores, Pangalis, Park, Richner, Robert H. Gilman, Silva, Sobonya, Sridhar, Sterling, Syed M. Hasan Rizvi   +36 more
core   +2 more sources

Primary effusion lymphoma: current perspectives

OncoTargets and Therapy, 2018
Primary effusion lymphoma (PEL) is a rare and aggressive disease, affecting a unique population of patients who are often elderly or immunocompromised. PEL is associated with human herpesvirus type-8 infection and most commonly presents as malignant effusions of the body cavities.
Mayur Narkhede, Shagun Arora, Chaitra Ujjani   +2 more
openaire   +4 more sources

Targeting Lactate and Lactylation in Cancer Metabolism and Immunotherapy

Advanced Science, EarlyView.
Lactate, once deemed a metabolic waste, emerges as a central regulator of cancer progression. This review elucidates how lactate and its epigenetic derivative, protein lactylation, orchestrate tumor metabolism, immune suppression, and therapeutic resistance.
Jiajing Gong, Yuhang Xie, Zhijie Weng, Yongzhi Wu, Longjiang Li, Bo Li   +5 more
wiley   +1 more source

Primary HHV-8 (-) Effusion-Based Non-Germinal Center B Cell Diffuse Large B Cell Lymphoma Successfully Treated with Standard Anthracycline-Based Chemoimmunotherapy

Journal of Blood Medicine, 2021
Justin Kuhlman,1 Muhamad Alhaj Moustafa,2 Liuyan Jiang,3 Han W Tun2 1Department of Internal Medicine, Mayo Clinic, Jacksonville, FL, USA; 2Division of Hematology and Medical Oncology, Mayo Clinic, Jacksonville, FL, USA; 3Department of Pathology and ...
Kuhlman J, Alhaj Moustafa M, Jiang L, Tun HW   +3 more
doaj