Results 101 to 110 of about 4,151,372 (299)

p, He, and C to Fe cosmic-ray primary fluxes in diffusion models: Source and transport signatures on fluxes and ratios

, 2010
The propagated fluxes of proton, helium, and heavier primary cosmic-ray species (up to Fe) are a means to indirectly access the source spectrum of cosmic rays.
A. Putze, Aguilar, Ahn, Ahn, Ahn, Ahn, Alcaraz, Alcaraz, Asakimori, Ave, Ave, Binns, Binns, Boezio, Boezio, Boulares, Caprioli, D. Maurin, Derbina, Diehl, Donato, Donato, Donato, Donato, Drury, Duvernois, Dwyer, Ellison, Engelmann, F. Donato, Ferrand, Ferrand, George, Gilmore, Gupta, Haino, Higdon, Ichimura, Ivanenko, Jones, Jones, Lemoine, Lionetto, Maurin, Maurin, Maurin, Menn, Meyer, Mueller, Nath, Ogliore, Osborne, Padovani, Panov, Perko, Ptuskin, Putze, Putze, Sanuki, Scherer, Seo, Shikaze, Strong, Swordy, Wang, Webber, Webber, Webber, Webber, Webber, Webber, Webber, Webber, Zatsepin, Zatsepin   +74 more
core   +3 more sources

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Assessing the Quality of Natural Gas Consumption Forecasting: An Application to the Italian Residential Sector

Energies, 2017
(1) Background: The present paper aims at estimating the quality of the forecasts obtained by using one equation models. In particular, the focus is on the effect that the explanatory variables have on the forecasted quantity.
Federico Scarpa, Vincenzo Bianco
doaj   +1 more source

Ultra high energy events in ECHOS series and primary energy spectrum [PDF]

The compilation of ultra high energy jets suggests at present the existence of a bump in primary energy spectrum (with the standard concept of high energy collisions). The pseudo-rapidity distribution exhibits some typical anomalies, more than the (P sub
Capdevielle, J. N., Iwai, J., Ogata, T.
core   +1 more source

Effects of the secondary decays on the isotopic thermometers

, 2000
The sharp microcanonical multifragmentation model from [Al. H. Raduta and Ad. R. Raduta, Phys. Rev. C 55, 1344 (1997); Phys. Rev. C, in press] is employed for evaluating the nuclear caloric curve predictions of nine isotopic thermometers for three ...
Ad.R Raduta, Al.H Raduta, Albergo, Bondorf, Gross, Hauger, Ma, Pochodzalla, Raduta, Raduta, Xi   +10 more
core   +2 more sources

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

Do primary energy resources influence industry location? [PDF]

By choosing to locate in a particular place, firms create employment opportunities for workers living there. And the wages they pay increase demand for local goods and services, creating additional job opportunities and further increasing the tax base ...
Jason P. Martinek, Michael J. Orlando
core  

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity

FEBS Open Bio, EarlyView.
Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz, Bruna Abreu, Cindy Mendes, Catarina Freitas‐Dias, Filipe Gonçalves, Fernanda Silva, José Ramalho, Saudade André, Vasco D. B. Bonifácio, Jacinta Serpa   +9 more
wiley   +1 more source