Results 121 to 130 of about 13,926,876 (298)

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

open access: yesFEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová   +2 more
wiley   +1 more source

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

open access: yesFEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose   +9 more
wiley   +1 more source

[Primary care: A definition of the field to develop research].

open access: yesRevue d'epidemiologie et de sante publique, 2018
Research in the field of primary care has dramatically increased in France in recent years, especially since 2013 with the introduction of primary care as a thematic priority for research proposals launched by the Ministry of Health (Direction générale de l'offre de soins).The RECaP (Research in Clinical Epidemiology and Public Health) network is a ...
Afonso, Mélanie   +12 more
openaire   +2 more sources

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

open access: yesFEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard   +12 more
wiley   +1 more source

Estimating the crop coefficient of meadow ecosystems and its driving factors using machine learning on the Qinghai–Tibet Plateau

open access: yesJournal of Hydrology: Regional Studies
Study region: Qinghai–Tibet Plateau (QTP), China Study focus: This study aims to improve crop coefficient (Kc) estimation for alpine meadows on the Qinghai–Tibet Plateau, where data scarcity and complex climate conditions make evapotranspiration (ET ...
Zhiming Xia   +3 more
doaj   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

open access: yesFEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya   +2 more
wiley   +1 more source

Measles Outbreak in Lambu Internally Displaced Persons´ Camp, Maiduguri, Borno State, Nigeria, 2017

open access: yesJournal of Interventional Epidemiology and Public Health
Introduction: Measles, a highly infectious disease caused by the Measles virus, is endemic in Nigeria. Although children are vaccinated against measles at the age of nine months which has led to a significant reduction in morbidity and mortality ...
Taiwo Israel Olasoju   +7 more
doaj   +1 more source

Evaluating the involvement of autolysosomes in the nuclear translocation of fluorescent proteins

open access: yesFEBS Open Bio, EarlyView.
Endogenously expressed fluorescent proteins can be degraded by autophagy and transported to cell nuclei via the nuclear pore complex. But in some cell lines, for example, HeLa cells which are positive for immunoreactivity of a receptor ligand, such as UCN I, in cell nuclei, fusion of autolysosome with the nuclear envelope is involved in the nuclear ...
Keiichi Ikeda
wiley   +1 more source

Cultural pathways to well-being in aging Japan: Exploring the meaning of “Good to Have Been Alive” through generativity, nature, and intergenerational connection

open access: yesInternational Psychogeriatrics
Objectives: This study examined the cultural and psychosocial foundations of well-being among older Japanese adults by focusing on the sentiment “good to have been alive,” a culturally embedded expression of life affirmation.
Kiichi Hirayama   +9 more
doaj   +1 more source

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