Results 101 to 110 of about 13,926,876 (298)

Catalyzing domestic financing for infection prevention and control through targeted budget advocacy: Implementation lessons from Nigeria

Journal of Interventional Epidemiology and Public Health
Introduction: Robust infection prevention and control (IPC) programs in healthcare settings are crucial for reducing the spread of infectious diseases and are key components of quality healthcare.
Aisha Sani Faruk, Tochi Okwor, Emmanuel Alhassan, Aminu Garba Magashi, Muzzammil Gadanya, Aisha Abba, Ibrahim Ozaki Suleiman, Elizabeth Bunmi Adedire, Chika Kemi Offor, Oliver Iorkase, Benson Omaiye, Celestine Ameh, Justine Landegger, Stacey Mearns, Jenom Danjuma, Celestina Awele Obiekea, Nanlop Ogbureke, Patrick Mboya Nguku, Moreen Kamateeka   +18 more
doaj   +1 more source

Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation

Molecular Oncology, EarlyView.
How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim, Alvin Kunyao Guo, Yoko Itahana, Srinivasaraghavan Kannan, Valerie Goh, Mingmin Ong, Terina Yan Wen Tay, Weiying Ye, Sabhashina Radha Krishnan, Jun Nishiyama, Chandra S Verma, Koji Itahana   +11 more
wiley   +1 more source

Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer

Molecular Oncology, EarlyView.
Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba, Mark Shacker, Timothy P. Fleming, Michael A. Smith, Ross M. Bremner, Narendra V. Sankpal   +5 more
wiley   +1 more source

Beyond viral load: Unravelling non-communicable disease patterns in Manicaland province, Zimbabwe

Journal of Public Health in Africa
Background: Non-communicable diseases (NCDs) among people living with human immunodeficient virus (HIV) are emerging and a leading cause of death in this population. Aim: To identify disease trends, prevalence and outcomes of NCDs among PLHIV. Setting: 
Kudzai F.V. Chokuona, Munyaradzi Mukuzunga, Tsitsi P. Juru, Addmore Chadambuka, Gerald Shambira, Notion T. Gombe, Mufuta Tshimanga   +6 more
doaj   +1 more source

Analysis of Primary Field Shielding Stability for the Weak Coupling Coil Designs. [PDF]

Sensors (Basel), 2020
Huang J, Wang H, Fu Z, Fu W.
europepmc   +1 more source

Ballymun primary care team strategy and progress report 2002-2007

, 2006
This report maps the progress to date of the Ballymun Primary Care Pilot in the context of a five year strategic plan covering the period from 2002- 2007.
Kenny, Mary
core  

Characterization of therapeutic antibodies targeting lymphatic and vascular resistance factor for the treatment of hypervascularized and highly metastatic cancers

Molecular Oncology, EarlyView.
LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David, Arthur Karaulic, Audrey Bennetot, Clémence Fournier, Quentin Odet, Arthur Gouraud, Isabelle Bourget, Cédric Gaggioli, Sandy Giuliano, Frédéric Luciano, Olivier Léger, Zaki Sellam, Gilles Pagès   +12 more
wiley   +1 more source

The Adolescent Girls and Young Women Initiative in Zimbabwe, 2018-2021: A secondary data analysis

Journal of Interventional Epidemiology and Public Health
Background: In Zimbabwe, the annual incidence of HIV among adolescent girls and young women (AGYW) is 9.5 times that of adolescent boys and young men. There is an AGYW initiative aimed at reducing new HIV infections among AGYW in Zimbabwe.
Godwin Choga, Owen Mugurungi, Tsitsi Patience Juru, Gibson Mandozana, Addmore Chadambuka, Notion Tafara Gombe, Gerald Shambira, Mufuta Tshimanga   +7 more
doaj   +1 more source

Theorization of New Practices in Emerging Organizational Fields

Vikalpa, 2017
Executive Summary Organizational actions are subject to multiple interpretations by the constituents of organizational field and are often prone to lose legitimacy in an uncertain environment.
Sushanta Kumar Sarma
doaj   +1 more source

Primary Decomposition of Modules: Two Variables over a Field

Journal of Symbolic Computation, 1993
Let \(k\) be a field. Let \(N\) be a submodule of the free \(k[x,y]\)-module \(k[x,y]^ s\) for some \(s>0\). First, the author gives a partial structure theorem for Gröbner bases of \(N\). Secondly, she presents an algorithm for computing the primary decomposition of \(N\subset k[x,y]^ s\).
openaire   +1 more source