Results 101 to 110 of about 33,684 (218)

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Measles Outbreak in Lambu Internally Displaced Persons´ Camp, Maiduguri, Borno State, Nigeria, 2017

Journal of Interventional Epidemiology and Public Health
Introduction: Measles, a highly infectious disease caused by the Measles virus, is endemic in Nigeria. Although children are vaccinated against measles at the age of nine months which has led to a significant reduction in morbidity and mortality ...
Taiwo Israel Olasoju, Mary Idowu Olasoju, Batula Bishara Daggash, Bio Belu Abaye, Chibuike Enumah, Salisu Isah1, Mohammed Tahiru Bolori, Oluwawemimo Oluseun Adebowale   +7 more
doaj   +1 more source

S-Field /Primary Singularity

S-Field/Primary ...
openaire   +2 more sources

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Cultural pathways to well-being in aging Japan: Exploring the meaning of “Good to Have Been Alive” through generativity, nature, and intergenerational connection

International Psychogeriatrics
Objectives: This study examined the cultural and psychosocial foundations of well-being among older Japanese adults by focusing on the sentiment “good to have been alive,” a culturally embedded expression of life affirmation.
Kiichi Hirayama, Carl Becker, Taizo Wada, Yasuko Ishimoto, Michiko Fujisawa, Yumi Kimura, Mitsuhiro Nose, Shigeru Ohtsuru, Kozo Matsubayashi, Ryota Sakamoto   +9 more
doaj   +1 more source

Suppression of lung adenocarcinoma migration through organelle alkalization by human lactoferrin – albumin fusion

FEBS Open Bio, EarlyView.
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia, Masahiro Kimura, Daisuke Kurimoto, Atsushi Sato   +3 more
wiley   +1 more source

Assessing the zero dose reduction operational plan strategy and its effects on immunization performance in priority local government areas in Nigeria a mixed methods implementation design

Discover Public Health
Background The Zero-Dose Operational Plan (Z-DROP) was implemented in 100 Local Government Areas (LGAs) across 18 states in Nigeria, targeting regions with the highest number of zero-dose children aged 0–23 months.
Daniel Ali, Muhammad Mashin, Rufai Garba Ahmed, Binta Aduke Ismail, Sulaiman Etamesor, Pius Angioha, Olasoji Fasogbon, Jamila Abubakar Umar, Adetola A. Adewumi, Daniel Daudu, George Gerlong, Abdulrasheed Abdulraheem, Affiong Simeon Ebong, Goodness T. Hadley, Janet B. Adegbola, Sulaiman A. Idris, Chizoba Wonodi   +16 more
doaj   +1 more source

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

FEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho, Rebecca Schmitt, Aneesha Dasgupta, Alexandra Ducharme, Jason Doles   +4 more
wiley   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

Versatile vector tools for efficient protein screening across multiple expression systems

FEBS Open Bio, EarlyView.
A unified vector toolkit enables rapid protein expression screening across E. coli, insect, and mammalian cells. A single primer pair amplifies the target gene, which is inserted into any vector via a standardized interface. This streamlined workflow eliminates repeated cloning steps, accelerating the identification of optimal expression conditions for
Zhimin Zhu, Yaqing Liu, Lei Qin, Feng Yu, Qisheng Wang, Yahui Liu   +5 more
wiley   +1 more source