Results 131 to 140 of about 6,045,153 (304)

Clinical profile and containment of the Ebola virus disease outbreak in two large West African cities, Nigeria, July–September 2014

International Journal of Infectious Diseases, 2016
Introduction: The Ebola virus disease (EVD) outbreak in Nigeria began when an infected diplomat from Liberia arrived in Lagos, the most populous city in Africa, with subsequent transmission to another large city.
Chima Ohuabunwo, Celestine Ameh, Oyin Oduyebo, Anthony Ahumibe, Bamidele Mutiu, Adebola Olayinka, Wasiu Gbadamosi, Erika Garcia, Carolina Nanclares, Wale Famiyesin, Abdulaziz Mohammed, Patrick Nguku, Richard I. Koko, Joshua Obasanya, Durojaye Adebayo, Yemi Gbadegesin, Oni Idigbe, Olukayode Oguntimehin, Sara Nyanti, Charles Nzuki, Ismail Abdus-Salam, Joseph Adeyemi, Nnanna Onyekwere, Emmanuel Musa, David Brett-Major, Faisal Shuaib, Abdulsalami Nasidi   +26 more
doaj   +1 more source

Ubiquitination of transcription factors in cancer: unveiling therapeutic potential

Molecular Oncology, EarlyView.
In cancer, dysregulated ubiquitination of transcription factors contributes to the uncontrolled growth and survival characteristics of tumors. Tumor suppressors are degraded by aberrant ubiquitination, or oncogenic transcription factors gain stability through ubiquitination, thereby promoting tumorigenesis.
Dongha Kim, Hye Jin Nam, Sung Hee Baek
wiley   +1 more source

Beyond viral load: Unravelling non-communicable disease patterns in Manicaland province, Zimbabwe

Journal of Public Health in Africa
Background: Non-communicable diseases (NCDs) among people living with human immunodeficient virus (HIV) are emerging and a leading cause of death in this population. Aim: To identify disease trends, prevalence and outcomes of NCDs among PLHIV. Setting: 
Kudzai F.V. Chokuona, Munyaradzi Mukuzunga, Tsitsi P. Juru, Addmore Chadambuka, Gerald Shambira, Notion T. Gombe, Mufuta Tshimanga   +6 more
doaj   +1 more source

Children who have received no routine polio vaccines in Nigeria: Who are they and where do they live?

Human Vaccines & Immunotherapeutics, 2017
Nigeria has made remarkable progress against polio, but 2 wild polio virus cases were reported in August 2016; putting an end to 2 y without reported cases.
Olalekan A. Uthman, Sulaimon T. Adedokun, Tawa Olukade, Samuel Watson, Olatunji Adetokunboh, Adeyinka Adeniran, Solomon A. Oyetoyan, Saheed Gidado, Stephen Lawoko, Charles S. Wiysonge   +9 more
doaj   +1 more source

Aberrant expression of nuclear prothymosin α contributes to epithelial‐mesenchymal transition in lung cancer

Molecular Oncology, EarlyView.
Nuclear prothymosin α inhibits epithelial‐mesenchymal transition (EMT) in lung cancer by increasing Smad7 acetylation and competing with Smad2 for binding to SNAI1, TWIST1, and ZEB1 promoters. In early‐stage cancer, ProT suppresses TGF‐β‐induced EMT, while its loss in the nucleus in late‐stage cancer leads to enhanced EMT and poor prognosis.
Liyun Chen, Chung‐Teng Wang, Jia‐Ming Chang, Ai‐Li Shiau, Gia‐Shing Shieh, Yau‐Lin Tseng, Yi‐Ting Yen, Tang‐Hsiu Huang, Li‐Hsin Cheng, Yu‐Chih Wu, Chao‐Liang Wu, Bing‐Hua Su, Pensee Wu   +12 more
wiley   +1 more source

Orbital parameters, chemical composition, and magnetic field of the Ap binary HD 98088

, 2013
HD 98088 is a synchronised, double-lined spectroscopic binary system with a magnetic Ap primary component and an Am secondary component. We study this rare system using high-resolution MuSiCoS spectropolarimetric data, to gain insight into the effect of ...
Alecian, E., Folsom, C. P., Kochukhov, O., Likuski, K., Shulyak, D., Wade, G. A.   +5 more
core   +2 more sources

Holomorphic primary fields in free CFT4 and Calabi-Yau orbifolds [PDF]

arXiv, 2017
Counting formulae for general primary fields in free four dimensional conformal field theories of scalars, vectors and matrices are derived. These are specialised to count primaries which obey extremality conditions defined in terms of the dimensions and left or right spins (i.e.
arxiv  

The Adolescent Girls and Young Women Initiative in Zimbabwe, 2018-2021: A secondary data analysis

Journal of Interventional Epidemiology and Public Health
Background: In Zimbabwe, the annual incidence of HIV among adolescent girls and young women (AGYW) is 9.5 times that of adolescent boys and young men. There is an AGYW initiative aimed at reducing new HIV infections among AGYW in Zimbabwe.
Godwin Choga, Owen Mugurungi, Tsitsi Patience Juru, Gibson Mandozana, Addmore Chadambuka, Notion Tafara Gombe, Gerald Shambira, Mufuta Tshimanga   +7 more
doaj   +1 more source

Systematic profiling of cancer‐fibroblast interactions reveals drug combinations in ovarian cancer

Molecular Oncology, EarlyView.
Fibroblasts, cells in the tumor environment, support ovarian cancer cell growth and alter morphology and drug response. We used fibroblast and cancer cell co‐culture models to test 528 drugs and discovered new drugs for combination treatment. We showed that adding Vorinostat or Birinapant to standard chemotherapy may improve drug response, suggesting ...
Greta Gudoityte, Osheen Sharma, Laura Leuenberger, Emelie Wallin, Josefin Fernebro, Päivi Östling, Rebecka Bergström, Johan Lindberg, Ulrika Joneborg, Olli Kallioniemi, Brinton Seashore‐Ludlow   +10 more
wiley   +1 more source

Clinton Maintains Lead In NH Democratic Primary Field, GOP A Muddle 10/9/14 [PDF]

, 2014
Hillary Clinton remains the frontrunner in the 2016 New Hampshire Primary. On the Republican side, there continues to be no frontrunner. Very few voters have made up their minds about who to vote for in the 2016 New Hampshire Primary.
Survey Center, UNH
core   +1 more source