Results 141 to 150 of about 5,811,196 (347)

Exploration of heterogeneity and recurrence signatures in hepatocellular carcinoma

open access: yesMolecular Oncology, EarlyView.
This study leveraged public datasets and integrative bioinformatic analysis to dissect malignant cell heterogeneity between relapsed and primary HCC, focusing on intercellular communication, differentiation status, metabolic activity, and transcriptomic profiles.
Wen‐Jing Wu   +15 more
wiley   +1 more source

Nursing interventions in personality disorders in the field of primary care

open access: yesINFAD, 2017
Introduction: The personality is defined as the dynamic set of emotional and behavioural characteristics that are unique to each person. According to the American Psychiatric Association (APA), personality disorders correspond to a set of signs that ...
Crescencio Pérez Murillo   +2 more
doaj   +1 more source

Holomorphic primary fields in free CFT4 and Calabi-Yau orbifolds [PDF]

open access: yesarXiv, 2017
Counting formulae for general primary fields in free four dimensional conformal field theories of scalars, vectors and matrices are derived. These are specialised to count primaries which obey extremality conditions defined in terms of the dimensions and left or right spins (i.e.
arxiv  

The atypical KRASQ22K mutation directs TGF‐β response towards partial epithelial‐to‐mesenchymal transition in patient‐derived colorectal cancer tumoroids

open access: yesMolecular Oncology, EarlyView.
TGF‐β has a complex role in cancer, exhibiting both tumor‐suppressive and tumor‐promoting properties. Using a series of differentiated tumoroids, derived from different stages and mutational background of colorectal cancer patients, we replicate this duality of TGF‐β in vitro. Notably, the atypical but highly aggressive KRASQ22K mutation rendered early‐
Theresia Mair   +17 more
wiley   +1 more source

Primary Atopic Disorders: Expanding Field of Inborn Errors of Immunity

open access: yesTurkish Journal of Immunology
Inborn errors of immunity cover a broad spectrum of diseases from immune deficiency syndromes to hyperinflammatory conditions. Primary atopic disorders are a recent member of this spectrum as a group that embracing monogenic immune deregulatory diseases ...
Güzin Özçifci   +3 more
doaj   +1 more source

Complete vector fields on (C-0)^n [PDF]

open access: yesarXiv, 1998
We prove necessary and sufficient conditions for completeness of a rational vector field on C^n minus n hyperplanes in general position (n>1).
arxiv  

Damping of ship-induced primary waves in groyne fields

open access: yes, 2021
Environmental Fluid ...
Pasman, R. (author)   +7 more
openaire   +4 more sources

Orbital parameters, chemical composition, and magnetic field of the Ap binary HD 98088

open access: yes, 2013
HD 98088 is a synchronised, double-lined spectroscopic binary system with a magnetic Ap primary component and an Am secondary component. We study this rare system using high-resolution MuSiCoS spectropolarimetric data, to gain insight into the effect of ...
Alecian, E.   +5 more
core   +2 more sources

Escape from TGF‐β‐induced senescence promotes aggressive hallmarks in epithelial hepatocellular carcinoma cells

open access: yesMolecular Oncology, EarlyView.
Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu   +11 more
wiley   +1 more source

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