Results 121 to 130 of about 1,558,129 (300)

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

A universal model for spike-frequency adaptation [PDF]

, 2003
Spike-frequency adaptation is a prominent feature of neural dynamics. Among other mechanisms, various ionic currents modulating spike generation cause this type of neural adaptation.
Andreas V. M. Herz, Benda, Jan, Jan Benda, Herz, Andreas V. M.   +3 more
core   +1 more source

Life Cycle Estimation of Battery Energy Storage Systems for Primary Frequency Regulation

Energies, 2018
An increasing share of renewable energy sources in power systems requires ad-hoc tools to guarantee the closeness of the system’s frequency to its rated value.
Natascia Andrenacci, Elio Chiodo, Davide Lauria, Fabio Mottola   +3 more
doaj   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Primary Frequency Control with Flywheel Energy Storage Technologies [PDF]

, 2017
Over the last decade, concerns about greenhouse gas emissions have increased. Different strategies have been developed to minimize those effects, leading to the development of renewable energy sources worldwide.
Peralta Moarry, Dario
core  

Optimizing Energy Storage Participation in Primary Frequency Regulation: A Novel Analytical Approach for Virtual Inertia and Damping Control in Low-Carbon Power Systems [PDF]

As renewable energy penetration increases, maintaining grid frequency stability becomes more challenging due to reduced system inertia. This paper proposes an analytical control strategy that enables distributed energy resources (DERs) to provide ...
Enkai Tan, Lefeng Cheng, Kuozhen Zhang, Wentian Lu, Wenjie Liu   +4 more
core   +1 more source

Optimization of Fuzzy Control Parameters for Wind Farms and Battery Energy Storage Systems Based on an Enhanced Artificial Bee Colony Algorithm under Multi-Source Sensor Data

Sensors
With the rapid development of sensors and other devices, precise control for the generation of new energy, especially in the context of highly stochastic wind power generation, has been strongly supported.
Zejian Liu, Ping Yang, Peng Zhang, Xu Lin, Jiaxi Wei, Ning Li   +5 more
doaj   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

Virtues and problems of the high C-field Cs beam frequency standard [PDF]

, 2000
Costanzo, Giovanni Antonio, M. Siccardi, Barychev, V., V. Barychev, De Marchi, Andrea, A. De Marchi, Siccardi, M., G.A. Costanzo   +7 more
core   +1 more source