Primary Headache Attributed to External Compression or Traction to the Head: A Narrative Review. [PDF]
Brain BehavHensel O, Kraya T.
europepmc +1 more source
An Intelligent Systems Approach to Primary Headache Diagnosis
International Conference on Intelligent Computing, 2017 Robert Keight +5 more
semanticscholar +1 more source
Development of a nalmefene formulation suitable for a community‐use auto‐injector
British Journal of Clinical Pharmacology, EarlyView.Aim Time to onset of reversal is critical when treating opioid‐induced respiratory depression and hypoxia. This study aimed to develop a formulation of the opioid antagonist nalmefene with an increased absorption rate and reduced time to onset of reversal following intramuscular administration. Methods Several absorption enhancers were screened in rats,
Alessandra Cipriano +6 more
wiley +1 more source
Strength Training and Posture Correction of the Neck and Shoulder for Patients with Chronic Primary Headache: A Prospective Single-Arm Pilot Study. [PDF]
J Clin MedPadrós-Augé J +5 more
europepmc +1 more source
Pharmacogenomics of dolutegravir: A scoping review of evidence, gaps and clinical implications
British Journal of Clinical Pharmacology, EarlyView.Dolutegravir underpins modern first‐ and second‐line HIV treatment regimens; however, interindividual variability in its disposition and tolerability presents challenges for optimal use. This scoping review mapped current evidence on the pharmacogenomics of dolutegravir, focusing on pharmacokinetics and pharmacodynamics, and methodological limitations ...
Ronald Kiguba +2 more
wiley +1 more source
Autonomic dysfunction in a patient with primary headache associated with sexual activity: case report and literature review. [PDF]
BMC NeurolZhang Y, Qian H, Yu S.
europepmc +1 more source
Plasma and breast milk pharmacokinetics of suvorexant in healthy lactating women
British Journal of Clinical Pharmacology, EarlyView.Aim This paper aims to evaluate the plasma and breast milk pharmacokinetics of suvorexant, an orexin receptor antagonist used to treat insomnia at a maximum dose of 20 mg, in healthy lactating women. Methods The paper reports on an open‐label Phase 1 study in 12 healthy lactating women.
Jacqueline McCrea +10 more
wiley +1 more source
Biomarkers in headaches as a potential solution to simplify differential diagnosis of primary headache disorders: a systematic review. [PDF]
J Headache PainGrodzka O +3 more
europepmc +1 more source
British Journal of Clinical Pharmacology, EarlyView.Abstract Cyclizine is a long‐established, short‐acting drug, registered for preventing motion sickness, post‐operative nausea and vomiting (PONV) and ‘vomiting of known cause’. The latter is not defined but may include pregnancy and patients receiving palliative care, historically accepted without large, controlled trials.
Gareth J. Sanger, Paul L. R. Andrews
wiley +1 more source
CYP3A5 genetic variability influences sildenafil and metabolite in pulmonary hypertension
British Journal of Clinical Pharmacology, EarlyView.Aim Interindividual variability in sildenafil response among pulmonary hypertension patients (PH) may be influenced by CYP3A5 polymorphisms. CYP3A5*3 allele reduces CYP3A5 activity and affects sildenafil metabolism. This study investigated the associations between CYP3A5 genotype and plasma concentrations of sildenafil and N‐desmethyl sildenafil, as ...
Pranisa Wongwien +7 more
wiley +1 more source