Results 51 to 60 of about 5,640,382 (269)

A Scoping Review and Meta‐Analysis of Proportions of Central Nervous System Manifestations Reported in Patients with Sjögren's Disease

Arthritis Care &Research, EarlyView.
Objective The objective of this scoping review was to synthesize evidence on the proportion of individuals living with Sjögren's disease who experience central nervous system (CNS) manifestations. Methods We searched MEDLINE (via PubMed) and Embase from 1980 through January 29, 2026, and the ECRI Guidelines Trust from 2020 through January 29, 2026 ...
Arun Varadhachary, Ghaith Noaiseh, Julie Frantsve‐Hawley, Frederick B. Vivino, Jennifer A. McCombe, Shamik Bhattacharyya, E. Sherwood Brown, Andrew R. Carey, Robert Fox, Thomas Grader‐Beck, Janet E. Lewis, Stephen Maitz, Steven Mandel, Astrid Rasmussen, George Sarka, R. Hal Scofield, Daniel J. Wallace, Rochelle Zak, Kristie Cox, Katherine M. Hammitt, Steven Carsons, Nancy Carteron   +21 more
wiley   +1 more source

Neuromodulators for Primary Headache Disorders: A Review [PDF]

, 2020
Primary headache disorders are among the most common and disabling globally. Pharmacological treatments are often insufficient, poorly tolerated, have side effects and the majority of patients are unable to complete their treatment.
Demosthenous, A, Salkim, E
core   +1 more source

Additional file 16: of Aids to management of headache disorders in primary care (2nd edition) [PDF]

, 2018
Instruments and other materials to aid diagnosis and management of headache disorders in primary care: Diagnostic headache diary.
Linde, Mattias, Katsarava, Z, M. Peters (3536831), Martelletti, P., Linde, M, M. Linde (6723083), Olesen, Jes, MacGregor, E. Anne, J. Olesen (6723092), Jensen, Rigmor Højland, Steiner, Timothy J., Peters, M, Peters, Michele, Katsarava, Zaza, V. Osipova (6723086), Osipova, Vera, Martelletti, Paolo, Martelletti, P, Osipova, V, Olesen, J., T. Steiner (4819209), K. Paemeleire (6723089), Steiner, TJ, Jensen, Rikke, Z. Katsarava (6723080), Steiner, T J, E. MacGregor (4855135), Paemeleire, Koen, MacGregor, EA, Olesen, J, MacGregor, E A, Paemeleire, K, P. Martelletti (6723095), R. Jensen (4855126), Jensen, R, Peters, M.   +35 more
core   +1 more source

Sex‐ and Time‐Resolved Physiological and Gut Ecosystem Responses to a Food‐Grade Microbiome‐Targeted Intervention in Collegiate Endurance Athletes

Advanced Science, EarlyView.
In collegiate endurance athletes, a 6‐week randomized CPYE intervention yielded time‐ and sex‐dependent shifts in field‐based cardiorespiratory, metabolic, and redox indices, accompanied by changes in gut multi‐omics profiles. An exploratory extension during intensified training generates hypotheses warranting future validation.
Meng Zhang, Le Ge, Kaiyang Liu, Yanrong Liu, Guolin Zhao, Lai‐Yu Kwok, Zheng Sun, Zhihong Sun, Wenyi Zhang   +8 more
wiley   +1 more source

Primary headaches: analysis of comorbidities associated with tension-type headaches

Headache Medicine, 2023
Full abstract in PDF.
Thiago Luís Marques Lopes, Arthur Vitor Couto de Sousa, Guilherme Matos da Penha, José Fernando Muniz Clarindo, Hildel Freire Leite Filho, Eduarda Lima Verde Ferreira   +5 more
doaj   +2 more sources

Spatial Transcriptomics Reveals a T Cell‐Mediated Microglial Activation Axis of Immune Checkpoint Inhibition‐Related Adverse Events in the Brain

Advanced Science, EarlyView.
Immune checkpoint inhibition (ICI) reshapes the hippocampal neuroimmune niche. Spatial transcriptomic profiling and human brain histological analyses identify neuroinflammation and altered neuronal and glial programs. Notably, T cell depletion prevents ICI‐driven microglial activation, establishing the T cell–microglia crosstalk axis as a driving ...
Devyani Swami, Sanad M. El‐Khatib, Suhas Sureshchandra, Elise Nguyen, Janaki Manoja Vinnakota, Robert Zeiser, Shivashankar Othy, Munjal M. Acharya   +7 more
wiley   +1 more source

Gastrointestinal Headache; a Narrative Review

Archives of Academic Emergency Medicine, 2018
There are studies reporting primary headaches to be associated with gastrointestinal disorders, and some report resolution of headache following the treatment of the associated gastrointestinal disorder.
Majid Noghani, Hossein Rezaeizadeh, Sayed Mohammad Baqer Fazljoo, Mahmoud Yousefifard, Mansoor Keshavarz   +4 more
doaj   +1 more source

Temporal‐Targeted Accelerated 40 Hz tACS Enhances Cognitive Function and Network Integration in Alzheimer's Disease: A Randomized Clinical Trial

Advanced Science, EarlyView.
Bilateral temporal accelerated 40‐Hz tACS improves cognitive function in patients with Alzheimer's disease. Resting‐state fNIRS identifies treatment‐related increases in frontotemporoparietal functional connectivity, which are associated with cognitive improvement. ABSTRACT The temporal lobes are key hubs for memory and cognition.
Rong Guo, Xingxing Li, Chenjun Zou, Chao Zheng, Xiaohong Wu, Xuechao Lu, Jiaying Yan, Junfang Zhang, Xiaoyan Luo, Shiwei Ye, Dongsheng Zhou   +10 more
wiley   +1 more source

Tension-Type Headache. Systematic review of the most widespread primary headache disorder.

Journal of Education, Health and Sport
Tension-type headache (TTH) is a primary headache disorder defined by the International Classification of Headache Disorders 3rd edition (ICHD-3) and is one of the most common types of headache worldwide.
Michał Hładki, Michalina Simachi, Michalina Janiszewska, Beata Imbirska, Marta Prager-Zimny, Michalina Cyrulik, Natalia Ramlau, Dominika Kolenda, Zuzanna Fischer, Marcin Podolak   +9 more
doaj   +1 more source

Inhibition of MEKK3 Prevents Cerebral Cavernous Malformation Progression Via Restoring Endothelial Integrity and Restricting Microglial Activation

Advanced Science, EarlyView.
In this study, we demonstrate that aberrant MEKK3 signaling in endothelial cells and microglia drives the progression of cerebral cavernous malformations (CCMs). Furthermore, we identify DPDH as a potent small‐molecule MEKK3 inhibitor with substantial therapeutic potential for CCM treatment.
Weiwei Zheng, Suyun Yu, Liwenyu Chen, Jing Ma, Peiliang Shen, Chang Yu, Xiaoqing Xin, Qiuhong Shen, Jing Chen, Song Ke, Hao Liu, Xiaobing Jiang, Ruogu Qi, Juming Yan, Jia Li, Jaesung P. Choi, Yin Lu, Yang Zhao   +17 more
wiley   +1 more source