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Genetics of primary headaches

Current Opinion in Neurology, 1999
Migraine has become an important topic in the field of complex genetic disorders. The identification of a gene on chromosome 19p encoding for an alpha 1A calcium channel subunit causing familial hemiplegic migraine has led to the classification of migraine as a channelopathy.
E E, Kors, J, Haan, M D, Ferrari
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Miscellaneous primary headache

Primary Care: Clinics in Office Practice, 2004
There are many types of miscellaneous primary headache, but two groups have been selected for discussion: trigeminal autonomic cephalalgias (TAC) and cephalalgias without autonomic dysfunction(CWAD). TAC are strictly unilateral and CWAD are usually bilateral.
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Primary cough headache

Current Pain and Headache Reports, 2005
Primary cough headache is defined as head pain brought on by coughing or other Valsalva maneuvers, but not by prolonged physical exercise, in the absence of any intracranial disorder. Primary cough headache is considered to be a rare condition, accounting for 0.4% of all headaches consulting our Neurology Department.
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Primary stabbing headache

2010
Primary stabbing headache is characterized by transient, cephalic ultrashort stabs of pain. It is a frequent complaint with a prevalence of 35.2%, a female preponderance, and a mean age of onset of 28 years (Vågå study). Attacks are generally characterized by moderate to severe, jabbing or stabbing pain, lasting from a fraction of a second to 3s ...
Juan A, Pareja, Ottar, Sjaastad
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Rare primary headaches

Current Opinion in Neurology, 2014
Little is known about most disorders classified as rare primary headaches. This review summarizes current knowledge about clinical presentation, pathophysiology, epidemiology and treatment options of rare headache disorders. Increasing public awareness on the different types of rare primary headache disorders may lead to more research and better ...
Holle, Dagny, Obermann, Mark
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Pathophysiology of primary headaches

Current Pain and Headache Reports, 2001
The cerebral circulation is innervated by sympathetic, parasympathetic, and sensory nerves, which store a considerable number of neurotransmitters. The role of these has been evaluated in primary headaches. A clear association between head pain and the release of calcitonin gene-related peptide was demonstrated.
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The “Other” Headaches: Primary Cough, Exertion, Sex, and Primary Stabbing Headaches

Current Pain and Headache Reports, 2010
Primary cough headache, primary exertional headache, primary sexual headache, and idiopathic stabbing headache are included in "Other Primary Headaches" (Group 4) in the International Classification of Headache Disorders, 2nd edition (ICHD-II). Headaches provoked by cough, exertion, and sex have different age distributions, but they do share some ...
Shuu-Jiun Wang, Jong-Ling Fuh
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The pathophysiology of primary headache

Primary Care: Clinics in Office Practice, 2004
Headache research has been a productive area, and understanding of primary headache pathophysiology has increased greatly. There are many more questions that need to be answered to gain a better understanding of the primary headache process. For the clinician,there is value in understanding the pathophysiology of primary headache, because this ...
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Primary Headache Disorders

Dental Clinics of North America, 2013
Primary headache disorders include migraine, tension-type headaches, and the trigeminal autonomic cephalgias (TACs). "Primary" refers to a lack of clear underlying causative pathology, trauma, or systemic disease. The TACs include cluster headache, paroxysmal hemicrania, and short-lasting neuralgiform headache attacks with conjunctival injection and ...
Rafael, Benoliel, Eli, Eliav
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The Hypothalamic Orexinergic System: Pain and Primary Headaches

open access: yesHeadache, 2007
The primary headaches are a group of distinct individually characterized attack forms, which although varying in presentation, share some common anatomical basis responsible for the pain component of the attack.
Philip R. Holland
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