Results 121 to 130 of about 20,558,786 (312)

Primary health care for Aboriginal and Torres Strait Islander children [PDF]

, 2015
This final report presents the findings from each of the phases of the Engaging Stakeholders in Identifying Priority Evidence-Practice Gaps and Strategies for Improvement in Primary Health Care (ESP) Project.
Alison Laycock, Jodie Bailie, Ross Bailie, Veronica Matthews   +3 more
core  

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Improving the �network planning and management� of integrated primary mental health care for older people in rural regions

, 2015
The research reported in this paper is a project of the Australian Primary Health Care Research Institute which is supported by a grant from the Australian Government Department of Health and Ageing under the Primary Health Care Research Evaluation and ...

core  

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

FEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Health Professional Underserved Areas Report, Kansas, 2013. Primary care underserved areas report, Kansas, 2013.

, 2014
INTRODUCTION: Kansas Population Density Peer Groups -- PART ONE: HEALTH CARE WORKFORCE SHORTAGE AREAS: Federal Primary Care HPSAs (Health Professional Shortage Areas); Federal Dental HPSAs (Health Professional Shortage Areas); Federal Mental Health HPSAs
Kansas. Primary Care Office.
core   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

Implementing screening programmes in primary care versus a centralised administration: a qualitative study of atrial fibrillation screening

BMC Primary Care
Background General practices have been tasked with increasing detection of atrial fibrillation (AF) to reduce stroke. Paroxysmal AF is often missed through usual care but can be detected through screening with repeated ECGs over a period of time using ...
Rakesh N Modi, Jonathan Mant, Kate Williams, Andrew Dymond, Jenni Burt   +4 more
doaj   +1 more source

What makes Care Plus effective in a provincial Primary Health Organisation? Perceptions of primary care workers.

, 2009
INTRODUCTION: Care Plus is a New Zealand chronic care initiative. It provides funding for extra primary care visits for patients with chronic diseases and aims to improve chronic care management, primary health care team work and reduce inequalities in ...
Kenealy, T, Eggleton, K
core   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

Political economy analysis of primary health care-oriented reforms: a case study on New Zealand

vi, 32 p.This case study examines the political economy of primary health care (PHC)-oriented health system reforms in New Zealand between 2000 and 2020, focusing on how political, institutional and historical factors influenced their design ...
World Health Organization
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