Results 111 to 120 of about 20,558,786 (312)

Health Record Application Forms PHC Remote

, 2018
The key purpose of these forms is to provide relevant authorisation for access to Primary Health Care Remote electronic health record systems.The Health Record Application Forms section includes: East Arnhem Communicare System (EACS) User Access ...

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Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Population health in primary care

Frontiers in Medicine
Population health in the United States continues to lag behind other wealthy nations. Primary care has the promise of enhancing population health; however, the implementation of a population health approach within primary care deserves further consideration.
David A. Haggstrom, David A. Haggstrom, David A. Haggstrom, Robert A. Gabbay, Robert A. Gabbay, William L. Miller, Jenna Howard, Benjamin F. Crabtree   +7 more
openaire   +4 more sources

Associations between ethnicity and mental health problems among children and adolescents in the United Kingdom: A systematic review and narrative synthesis

BMC Public Health
Background The associations between ethnicity and mental health problems (MHPs) among children and adolescents in the UK have been reported in recent years.
Shengjia Guan, Barry Coughlan, Kate Evans, Robbie Duschinsky   +3 more
doaj   +1 more source

Optimising access to best practice primary health care: a systematic review [PDF]

, 2009
Ensuring that Australians have access to health care is an integral component of Australian health care policy. Growing awareness of the importance of primary health care (PHC) in delivering equitable and cost-effective care is creating interest in ...
Furler, John, Harris, Mark, Christl, Bettina, Haas, Marion, Krastev, Yordanka, Powell Davies, Gawaine, Comino, Elizabeth, Hall, Jane, Raymont, Antony   +8 more
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Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Prevalence, diagnosis gap, and treatment patterns of hypertension in a primary care electronic health record cohort in Qatar: a retrospective cross-sectional study

BMC Primary Care
Background Hypertension is a major global public health concern and a leading contributor to cardiovascular and renal morbidity and mortality. In Qatar, diverse expatriate populations constitute a large proportion of Primary Health Care Corporation (PHCC)
Melis Dorter, Ahmad Eid, Naela Darwish Saad   +2 more
doaj   +1 more source

Political economy analysis of primary health care-oriented reforms: a case study of primary care networks in Kenya

vi, 21 p.Kenya’s primary health care (PHC) reform aims to support the country’s commitment to achieving universal health coverage by 2030 through the establishment of primary care networks.
World Health Organization
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