Results 91 to 100 of about 5,298,526 (303)
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
GEOGRAPHIC PROFILE OF HEALTHCARE NEEDS AND NON-ACUTE HEALTHCARE SUPPLY IN IRELAND. ESRI RESEARCH SERIES NUMBER 90 JULY 2019 [PDF]
, 2019 This report provides evidence on the supply of and need for non-acute primary, community and long-term care across geographic areas in Ireland in 2014.
Barron, Steve +6 more
core
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Neuroborreliosis in an immunosuppressed patient
Iberoamerican Journal of MedicineNeuroborreliosis is a rare but significant manifestation of Lyme disease, particularly in immunosuppressed individuals. We present the case of a 43-year-old patient with a history of follicular lymphoma in remission, currently undergoing maintenance ...
Alodia Rodríguez-Nájera +4 more
doaj +1 more source
Improving Child Health Care Through Federal Policy: An Emerging Opportunity [PDF]
, 2008 Summarizes legislative proposals introduced in 2007 to track primary care outcomes in Medicaid and State Children's Health Insurance Programs (SCHIP) and focus on strengthening primary, preventive, and developmental child health services and ...
Carla Plaza +2 more
core
Development and validation of the Vietnamese Primary Care Assessment Tool : provider version
, 2019 Aim: To adapt the provider version of the Primary Care Assessment Tool (PCAT) for Vietnam and determine its internal consistency and validity. Background: There is a growing need to measure and explore the impact of various characteristics of health care
Derese, Anselme +4 more
core +2 more sources
Fetal Brain Tumor Harboring a Unique ROCK1::BRAF Fusion
Pediatric Blood &Cancer, EarlyView.
Marllon Cindra Sant'Ana +8 more
wiley +1 more source
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
FEBS Letters, EarlyView.Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source