Results 141 to 150 of about 6,981,203 (402)

Unpaid carers’ access to and use of primary care services [PDF]

, 2005
GPs and members of the primary care team have a pivotal role in supporting unpaid carers in their caring role and helping them to maintain their own health and well-being.
Arksey, Hilary, Hirst, Michael Anthony
core   +1 more source

Improving pathways to primary health care among LGBTQ populations and health care providers: key findings from Nova Scotia, Canada

International Journal for Equity in Health, 2018
BackgroundThis study explores the perceived barriers to primary health care as identified among a sample of Lesbian, Gay, Bisexual, Transgender, and Queer (LGBTQ) identified individuals and health care providers in Nova Scotia, Canada.
J. Gahagan, Montse Subirana-Malaret
semanticscholar   +1 more source

Transcriptome‐wide analysis of circRNA and RBP profiles and their molecular relevance for GBM

Molecular Oncology, EarlyView.
CircRNAs are differentially expressed in glioblastoma primary tumors and might serve as therapeutic targets and diagnostic markers. The investigation of circRNA and RNA‐binding proteins (RBPs) interactions shows that distinct RBPs play a role in circRNA biogenesis and function.
Julia Latowska‐Łysiak, Żaneta Zarębska, Marcin P. Sajek, Adriana Grabowska, Alessia Buratin, Paweł Głodowicz, Julia O. Misiorek, Konrad Kuczyński, Stefania Bortoluzzi, Marek Żywicki, Jan G. Kosiński, Agnieszka Rybak‐Wolf, Rafał Piestrzeniewicz, Anna M. Barciszewska, Katarzyna Rolle   +14 more
wiley   +1 more source

Expanding Paramedicine in the Community (EPIC): study protocol for a randomized controlled trial. [PDF]

, 2014
BackgroundThe incidence of chronic diseases, including diabetes mellitus (DM), heart failure (HF) and chronic obstructive pulmonary disease (COPD) is on the rise.
Atzema, Clare L, Barrette, Norm, Dainty, Katie N, Drennan, Ian R, Farrell, Melissa, Filosa, Tom, Hawker, Gillian, Hoch, Jeffrey S, Hoogeveen, Paul, Isaranuwatchai, Wanrudee, Kane, Jennifer, Kiss, Alex, Morrison, Laurie J, Philpott, Jane, Spearen, Chris, Tavares, Walter, Turner, Linda   +16 more
core   +2 more sources

Outness, Stigma, and Primary Health Care Utilization among Rural LGBT Populations

PLoS ONE, 2016
Background Prior studies have noted significant health disadvantages experienced by LGBT (lesbian, gay, bisexual, and transgender) populations in the US.
Jennifer Whitehead, J. Shaver, R. Stephenson   +2 more
semanticscholar   +1 more source

Targeting the MDM2‐MDM4 interaction interface reveals an otherwise therapeutically active wild‐type p53 in colorectal cancer

Molecular Oncology, EarlyView.
This study investigates an alternative approach to reactivating the oncosuppressor p53 in cancer. A short peptide targeting the association of the two p53 inhibitors, MDM2 and MDM4, induces an otherwise therapeutically active p53 with unique features that promote cell death and potentially reduce toxicity towards proliferating nontumor cells.
Sonia Valentini, Giada Mele, Marika Attili, Maria Rita Assenza, Fulvio Saccoccia, Francesca Sardina, Cinzia Rinaldo, Roberto Massari, Nicola Tirelli, Alfredo Pontecorvi, Fabiola Moretti   +10 more
wiley   +1 more source

Does quality influence utilization of primary health care? Evidence from Haiti

Globalization and Health, 2018
BackgroundExpanding coverage of primary healthcare services such as antenatal care and vaccinations is a global health priority; however, many Haitians do not utilize these services.
Anna D. Gage, H. Leslie, A. Bitton, J. Jerome, Jean Paul Joseph, Roody Thermidor, M. Kruk   +6 more
semanticscholar   +1 more source

Thermal proteome profiling and proteome analysis using high‐definition mass spectrometry demonstrate modulation of cholesterol biosynthesis by next‐generation galeterone analog VNPP433‐3β in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Elevated level of cholesterol is positively correlated to prostate cancer development and disease severity. Cholesterol‐lowering drugs, such as statins, are demonstrated to inhibit prostate cancer. VNPP433‐3β interrupts multiple signaling and metabolic pathways, including cholesterol biosynthesis, AR‐mediated transcription of several oncogenes, mRNA 5′
Retheesh S. Thankan, Elizabeth Thomas, Mehari M. Weldemariam, Puranik Purushottamachar, Weiliang Huang, Maureen A. Kane, Yuji Zhang, Nicholas Ambulos, Bi‐Dar Wang, David Weber, Vincent C. O. Njar   +10 more
wiley   +1 more source

Associations between ethnicity and mental health problems among children and adolescents in the United Kingdom: A systematic review and narrative synthesis

BMC Public Health
Background The associations between ethnicity and mental health problems (MHPs) among children and adolescents in the UK have been reported in recent years.
Shengjia Guan, Barry Coughlan, Kate Evans, Robbie Duschinsky   +3 more
doaj   +1 more source

Consultation patterns of children and adolescents with knee pain in UK general practice: analysis of medical records

BMC Musculoskeletal Disorders, 2017
Background Knee problems are common in children and adolescents. Despite this, little is known about the epidemiology of knee problems in children and adolescents who consult in general practice.
Zoe A. Michaleff, Paul Campbell, Joanne Protheroe, Amit Rajani, Kate M. Dunn   +4 more
doaj   +1 more source