Results 151 to 160 of about 6,981,203 (402)

Primary Health Care as a Foundation for Strengthening Health Systems in Low- and Middle-Income Countries

open access: yesJournal of general internal medicine, 2016
Primary health care (PHC) has been recognized as a core component of effective health systems since the early part of the twentieth century. However, despite notable progress, there remains a large gap between what individuals and communities need, and ...
A. Bitton   +13 more
semanticscholar   +1 more source

Highly multiplexed digital PCR assay for simultaneous quantification of variant allele frequencies and copy number alterations of KRAS and GNAS in pancreatic cancer precursors

open access: yesMolecular Oncology, EarlyView.
Combining melting curve analysis enhances the multiplexing capability of digital PCR. Here, we developed a 14‐plex assay to simultaneously measure single nucleotide mutations and amplifications of KRAS and GNAS, which are common driver genes in pancreatic cancer precursors. This assay accurately quantified variant allele frequencies in clinical samples
Junko Tanaka   +10 more
wiley   +1 more source

Social Media And Health: Implications For Primary Health Care Providers [PDF]

open access: yes, 2010
This report is the second deliverable of the ?Digital Inclusion and Social Knowledge Media for Health: Frameworks and Roadmaps? project. The first discussed the concept of social and digital exclusion whilst this report focuses on the emerging phenomenon
Anderson, B, Speed, E
core  

Change in physical activity level and clinical outcomes in older adults with knee pain: a secondary analysis from a randomised controlled trial

open access: yesBMC Musculoskeletal Disorders, 2018
Background Exercise interventions improve clinical outcomes of pain and function in adults with knee pain due to osteoarthritis and higher levels of physical activity are associated with lower severity of pain and higher levels of physical functioning in
Jonathan G. Quicke   +4 more
doaj   +1 more source

Nursing competency standards in primary health care: an integrative review.

open access: yesJournal of Clinical Nursing, 2016
AIMS AND OBJECTIVES This paper reports an integrative review of the literature on nursing competency standards for nurses working in primary health care and, in particular, general practice.
E. Halcomb   +4 more
semanticscholar   +1 more source

Exploration of heterogeneity and recurrence signatures in hepatocellular carcinoma

open access: yesMolecular Oncology, EarlyView.
This study leveraged public datasets and integrative bioinformatic analysis to dissect malignant cell heterogeneity between relapsed and primary HCC, focusing on intercellular communication, differentiation status, metabolic activity, and transcriptomic profiles.
Wen‐Jing Wu   +15 more
wiley   +1 more source

Primary Care Staff's Views and Experiences Related to Routinely Advising Patients about Physical Activity. A Questionnaire Survey [PDF]

open access: yes, 2006
Background: United Kingdom public health policy has recently re-emphasised the role of primary health care professionals in tackling increasing levels of physical inactivity within the general population.
A Steptoe   +36 more
core   +4 more sources

Subgrouping patients with sciatica in primary care for matched care pathways: development of a subgrouping algorithm

open access: yesBMC Musculoskeletal Disorders, 2019
Background Sciatica is a painful condition managed by a stepped care approach for most patients. Currently, there are no decision-making tools to guide matching care pathways for patients with sciatica without evidence of serious pathology, early in ...
Kika Konstantinou   +6 more
doaj   +1 more source

A qualitative study on African immigrant and refugee families’ experiences of accessing primary health care services in Manitoba, Canada: it’s not easy!

open access: yesInternational Journal for Equity in Health, 2017
BackgroundImmigrant and refugee families form a growing proportion of the Canadian population and experience barriers in accessing primary health care services.
R. Woodgate   +5 more
semanticscholar   +1 more source

A large‐scale retrospective study in metastatic breast cancer patients using circulating tumour DNA and machine learning to predict treatment outcome and progression‐free survival

open access: yesMolecular Oncology, EarlyView.
There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes   +20 more
wiley   +1 more source

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