Results 41 to 50 of about 2,047,237 (309)

Impact of Multi-Disciplinary Team in Implementing Clinical Audit Recommendations to Improve Health Educators’ Practice at Primary Care in Qatar

Journal of Primary Care & Community Health
Background: Health educators play a vital role in primary care by educating patients on the significance of maintaining good health and preventive measures, especially in the case of chronic illnesses.
Ansif Pallath Majeed, Kiran Harikumar, Hanan Al Mujalli, Abdul Ali Shah, Noora Alkubaisi, Sharifullah Khan, Faiza Aiman   +6 more
doaj   +1 more source

Protonophore activity of short‐chain fatty acids induces their intracellular accumulation and acidification

FEBS Letters, EarlyView.
The protonated form of butyrate, as well as other short‐chain fatty acids (SCFAs), is membrane permeable. In acidic extracellular environments, this can lead to intracellular accumulation of SCFAs and cytosolic acidification. This phenomenon will be particularly relevant in acidic environments such as the large intestine or tumor microenvironments ...
Muwei Jiang, Frans Bianchi, Geert van den Bogaart   +2 more
wiley   +1 more source

When investigating depression and anxiety in undergraduate medical students timing of assessment is an important factor - a multicentre cross-sectional study

BMC Medical Education, 2020
Background Symptoms of depression and anxiety experienced by undergraduate medical students have become a prominent concern. Evidence about students’ depression and anxiety including prevalence, trajectory during medical education, gender differences and
Pia Thiemann, James Brimicombe, John Benson, Thelma Quince   +3 more
doaj   +1 more source

B cell mechanobiology in health and disease: emerging techniques and insights into therapeutic responses

FEBS Letters, EarlyView.
B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro, Marco Cellani, Cristina Scielzo   +2 more
wiley   +1 more source

“It’s Difficult, There’s No Formula”: Qualitative Study of Stroke Related Communication Between Primary and Secondary Healthcare Professionals

International Journal of Integrated Care, 2020
Introduction: Stroke survivors have complex health needs requiring long-term, integrated care. This study aimed to elicit generalists’ and specialists’ experience of stroke-related interprofessional communication, including perceived barriers and ...
Maria Raisa Jessica (Ryc) Aquino, Ricky Mullis, Caroline Moore, Elizabeth Kreit, Lisa Lim, Christopher McKevitt, Bundy Mackintosh, Jonathan Mant   +7 more
doaj   +1 more source

Circulating histones as clinical biomarkers in critically ill conditions

FEBS Letters, EarlyView.
Circulating histones are emerging as promising biomarkers in critical illness due to their diagnostic, prognostic, and therapeutic potential. Detection methods such as ELISA and mass spectrometry provide reliable approaches for quantifying histone levels in plasma samples.
José Luis García‐Gimenez, Juan Carlos Ruiz‐Rodríguez, Ricard Ferrer, Raquel Durá, Antonio Artigas, Iván Bajaña, David Bolado López de Andujar, Irene Cánovas‐Cervera, Adrián Ceccato, Luis Chiscano‐Camón, Elena Climent‐Martinez, Georgia García Fernández, Gemma Goma, Verónica Monforte, Beatriz Quevedo‐Sánchez, Adolf Ruiz‐Sanmartín, Antonio Sierra‐Rivera, Nieves Carbonell Monleón   +17 more
wiley   +1 more source

Dietary fat intake and quality in long-term care residents in two cohorts assessed 10 years apart

BMC Nutrition, 2022
Purpose To describe and compare detailed dietary fat intake, fat quality and associative factors between two measuring points 10 years apart of residents living in long-term care facilities, and to reflect how fat composition and fat quality corresponds ...
K. Jyväkorpi Satu, H. Suominen Merja, E. Strandberg Timo, Karoliina Salminen, T. Niskanen Riikka, Hanna-Maria Roitto, K. T. Saarela Riitta, H. Pitkälä Kaisu   +7 more
doaj   +1 more source

Insights into pegRNA design from editing of the cardiomyopathy‐associated phospholamban R14del mutation

FEBS Letters, EarlyView.
This study reveals how prime editing guide RNA (pegRNA) secondary structure and reverse transcriptase template length affect prime editing efficiency in correcting the phospholamban R14del cardiomyopathy‐associated mutation. Insights support the design of structurally optimized enhanced pegRNAs for precise gene therapy.
Bing Yao, Qiangbing Yang, Christian J.B. Snijders Blok, Mark A. Daniels, Pieter A. Doevendans, Raymond Schiffelers, Joost P.G. Sluijter, Zhiyong Lei   +7 more
wiley   +1 more source

Antibiotic use and the risk of rheumatoid arthritis: a population-based case-control study

BMC Medicine, 2019
Background Antibiotic-induced disturbances of the human microbiota have been implicated in the development of chronic autoimmune conditions. This study aimed to assess whether antibiotic use is associated with the onset of rheumatoid arthritis (RA ...
Alyshah Abdul Sultan, Christian Mallen, Sara Muller, Samantha Hider, Ian Scott, Toby Helliwell, Lindsay J. Hall   +6 more
doaj   +1 more source

Developing best practices for PPE Portraits across 25 sites: a systematic assessment of implementation and spread of adaptations using FRAME

BMC Health Services Research, 2021
Background Adaptation, a form of modification that aims to improve an intervention’s acceptability and sustainability in each context, is essential to successful implementation in some settings.
Juliana Baratta, Alexis Amano, Paige K Parsons, Stacie Vilendrer, Shira G. Winter, Mae-Richelle Verano, Cynthia Perez, Lucy Kalanithi, Steven M Asch, Mary Beth Heffernan, Cati Brown-Johnson   +10 more
doaj   +1 more source