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Primary Hyperparathyroidism [PDF]

Journal of Clinical Endocrinology and Metabolism, 2018
Background Primary hyperparathyroidism (PHPT), the most common cause of hypercalcemia, is most often identified in postmenopausal women. The clinical presentation of PHPT has evolved over the past 40 years to include three distinct clinical phenotypes ...
John P Bilezikian
exaly   +25 more sources

Primary hyperparathyroidism [PDF]

Nature Reviews Disease Primers, 2016
Primary hyperparathyroidism is a common endocrine disorder caused by overactivation of parathyroid glands resulting in excessive release of parathyroid hormone. The resultant hypercalcemia leads to a myriad of symptoms. Primary hyperparathyroidism may increase a patient's morbidity and even mortality if left untreated.
John P Bilezikian, Aliya A Khan, Jian-min Liu   +2 more
exaly   +15 more sources

Primary hyperparathyroidism

Endokrynologia Polska, 2020
Primary hyperparathyroidism is an endocrine disorder that results in overproduction of parathyroid hormone by overactivated parathyroid gland leading to a significant rise in blood serum calcium.
Grzegorz J. Kowalski, Grzegorz Buła, Dominika Żądło, Agata Gawrychowska, Jacek Gawrychowski   +4 more
doaj   +7 more sources

Normocalcemic primary hyperparathyroidism

Archives of Endocrinology and Metabolism, 2022
Normocalcemic primary hyperparathyroidism (PHPT) is a newer phenotype of PHPT defined by elevated PTH concentrations in the setting of normal serum calcium levels.
Natalie E. Cusano, Filomena Cetani
doaj   +2 more sources

Evaluation and Management of Primary Hyperparathyroidism: Summary Statement and Guidelines from the Fifth International Workshop

Journal of Bone and Mineral Research, 2022
The last international guidelines on the evaluation and management of primary hyperparathyroidism (PHPT) were published in 2014. Research since that time has led to new insights into epidemiology, pathophysiology, diagnosis, measurements, genetics ...
John P Bilezikian, Aliya A Khan, Shonni J Silverberg   +2 more
exaly   +2 more sources

Epidemiology, Pathophysiology, and Genetics of Primary Hyperparathyroidism

Journal of Bone and Mineral Research, 2022
In this narrative review, we present data gathered over four decades (1980–2020) on the epidemiology, pathophysiology and genetics of primary hyperparathyroidism (PHPT).
Salvatore Minisola, Andrew Arnold, Maria Luisa Brandi   +2 more
exaly   +2 more sources

Primary hyperparathyroidism [PDF]

Clinical Case Reports, 2019
Key Clinical Message We report a case of hyperparathyroidism with hypercalcemia caused by a giant parathyroid adenoma. We use a technetium sestamibi scan to locate parathyroid mass.
Ao Wang, Lei Yuan
doaj   +3 more sources

Comparison of first- and second-line imaging diagnostics (ultrasound + scintigraphy and PET + 4DCT) in visualizing parathyroid glands in primary hyperparathyroidism including ectopic foci

Journal of Education, Health and Sport
Introduction: Primary hyperparathyroidism is an endocrine disorder that causes disturbances in calcium and phosphorus metabolism in the human body.
Laura Loryś, Klaudia Klimczak, Kamila Budzyńska, Marcin Narloch, Stanisław Kasprzak, Karolina Kasprzak, Jakub Kamiński, Norbert Kandefer   +7 more
doaj   +3 more sources

Should Symptoms Be Considered an Indication for Parathyroidectomy in Primary Hyperparathyroidism?

Clinical Medicine Insights: Endocrinology and Diabetes, 2018
Asymptomatic primary hyperparathyroidism is a very common endocrine condition, yet management of this disease process remains controversial. Primary hyperparathyroidism can lead to a myriad of symptoms which not only decreases the quality of life of ...
Alexandria D McDow, Rebecca S Sippel
doaj   +2 more sources

Impact of Parathyroidectomy on Kidney Function in Adults With Primary Hyperparathyroidism. [PDF]

Cureus
Bandovas JP, Candeias H, Mourão M, Dhanani A, Monteiro N, Crespo A, Tavares P, Pinto Marques H.   +7 more
europepmc   +3 more sources