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Primary Hyperparathyroidism: An Overview [PDF]
Primary hyperparathyroidism is a common condition that affects 0.3% of the general population. Primary and tertiary care specialists can encounter patients with primary hyperparathyroidism, and prompt recognition and treatment can greatly reduce ...
Anderson, Donald+4 more
core +8 more sources
Primary Hyperparathyroidism [PDF]
Abstract Primary hyperparathyroidism is a common endocrine disease characterized by excessive secretion of parathyroid hormone from one or more of the four parathyroid glands. In most patients, a single, benign adenoma is responsible for the disease, but in a small percentage of subjects, four-gland hyperplasia is evident.
J. Bilezikian
semanticscholar +12 more sources
Primary hyperparathyroidism [PDF]
Primary hyperparathyroidism is a common endocrine disorder caused by overactivation of parathyroid glands resulting in excessive release of parathyroid hormone. The resultant hypercalcemia leads to a myriad of symptoms. Primary hyperparathyroidism may increase a patient's morbidity and even mortality if left untreated.
Madkhali, Tarıq+3 more
semanticscholar +12 more sources
Primary hyperparathyroidism [PDF]
Key Clinical MessageWe report a case of hyperparathyroidism with hypercalcemia caused by a giant parathyroid adenoma. We use a technetium sestamibi scan to locate parathyroid mass. Bone emission computed tomography revealed the classic signs of metabolic osteopathy. She was recovered after parathyroidectomy.
Ao Wang, Lei Yuan
openaire +3 more sources
Primary hyperparathyroidism (PHPT), the most common cause of hypercalcemia, is most often identified in postmenopausal women with hypercalcemia and parathyroid hormone (PTH) levels that are either frankly elevated or inappropriately normal. The clinical presentation of PHPT includes three phenotypes: target organ involvement of the renal and skeletal ...
Aimee N, diMarco+2 more
semanticscholar +14 more sources
Primary hyperparathyroidism [PDF]
In this Review, we describe the pathogenesis, diagnosis and management of primary hyperparathyroidism (PHPT), with a focus on recent advances in the field. PHPT is a common endocrine disorder that is characterized by hypercalcaemia and elevated or inappropriately normal serum levels of parathyroid hormone.
Marcella D, Walker, Shonni J, Silverberg
openaire +3 more sources
Normocalcemic primary hyperparathyroidism
Normocalcemic primary hyperparathyroidism (PHPT) is a newer phenotype of PHPT defined by elevated PTH concentrations in the setting of normal serum calcium levels. It is increasingly being diagnosed in the setting of evaluation for nephrolithiasis or metabolic bone diseases.
Natalie E. Cusano, Filomena Cetani
openaire +5 more sources
Should Symptoms Be Considered an Indication for Parathyroidectomy in Primary Hyperparathyroidism?
Asymptomatic primary hyperparathyroidism is a very common endocrine condition, yet management of this disease process remains controversial. Primary hyperparathyroidism can lead to a myriad of symptoms which not only decreases the quality of life of ...
Alexandria D McDow, Rebecca S Sippel
doaj +2 more sources
Biochemistry in Symptomatic and Asymptomatic Primary Hyperparathyroidism: A Cross-Sectional Study
Background: PHPT can be symptomatic or asymptomatic, according to the presence of classic symptoms (skeletal or renal involvement), without conclusive evidence of its relation to biochemical parameters.
Tania K. Cázares Robles+4 more
doaj +1 more source
The last international guidelines on the evaluation and management of primary hyperparathyroidism (PHPT) were published in 2014. Research since that time has led to new insights into epidemiology, pathophysiology, diagnosis, measurements, genetics ...
J. Bilezikian+13 more
semanticscholar +1 more source