Primary hyperparathyroidism [PDF]
Primary hyperparathyroidism (PHPT) is a condition that affects calcium metabolism due to parathyroid hormone (PTH) hypersecretion leading to hypercalcemia. Manifestations have changed over time, from a symptomatic disease with bone pain, fractures, nephrolithiasis, and muscle weakness, to a condition that is mainly asymptomatic (80-90%).
Júlia V, Oberger Marques+1 more
core +6 more sources
Substernal oxyphil parathyroid adenoma producing PTHrP with hypercalcemia and normal PTH level [PDF]
Background Parathyroid adenoma is the most common cause of primary hyperparathyroidism. Preoperative serum calcium and intact-parathyroid hormone levels are the most useful diagnostic parameters that allow differentiating primary hyperparathyroidism from
Rubini Domenico+6 more
doaj +5 more sources
Post-surgical follow-up of primary hyperparathyroidism associated with multiple endocrine neoplasia type 1 [PDF]
The bone mineral density increments in patients with sporadic primary hyperparathyroidism after parathyroidectomy have been studied by several investigators, but few have investigated this topic in primary hyperparathyroidism associated with multiple ...
Flavia L. Coutinho+4 more
doaj +13 more sources
Unmasking of normocalcemic primary hyperparathyroidism after sodium-glucose cotransporter-2 inhibitor initiation [PDF]
Sodium-glucose cotransporter-2 (SGLT2) inhibitors have complex interactions with bone metabolism, including an increase in parathyroid hormone (PTH) levels.
Christodoulos Dolapsakis+2 more
doaj +2 more sources
Primary Hyperparathyroidism in Pregnancy: Successful Parathyroidectomy during First Trimester [PDF]
Primary hyperparathyroidism in pregnancy can result in significant maternal and fetal complications. When indicated, prompt parathyroidectomy in the early second trimester is considered the treatment of choice.
Niranjan Tachamo+5 more
doaj +3 more sources
Primary hyperparathyroidism in multiple endocrine neoplasia type 1: when to perform surgery? [PDF]
Primary hyperparathyroidism is a common endocrinological disorder. In rare circumstances, it is associated with familial syndromes, such as multiple endocrine neoplasia type 1.
Francesca Giusti+2 more
doaj +5 more sources
Primary Hyperparathyroidism in Patients with Multiple Endocrine Neoplasia Type 1 [PDF]
Primary hyperparathyroidism may occur as a part of an inherited syndrome in a combination with pancreatic endocrine tumours and/or pituitary adenoma, which is classified as Multiple Endocrine Neoplasia type 1 (MEN-1).
Grzegorz Piecha+2 more
doaj +4 more sources
Recurrent Bilateral Staghorn Stones as a Manifestation of Primary Hyperparathyroidism due to Parathyroid Adenoma [PDF]
Primary hyperparathyroidism is a medical condition caused by overactive of parathyroid gland. It is most commonly caused by solitary adenoma of the parathyroid gland.
Laurentius A Pramono+4 more
doaj +3 more sources
Numerous T wave morphology biomarkers, which can supplement QTc assessment in long QT syndrome (LQTS), have been identified. Their diagnostic capabilities include differentiation of genotypes, identification of concealed LQTS, differentiating acquired LQTS from congenital LQTS; and determining multichannel versus hERG channel blockade.
Daniel T. Tardo+4 more
wiley +1 more source
Primary hyperparathyroidism: diagnostics and surgical management
Primary hyperparathyroidism is an endocrinological pathology of parathyroid glands. Its predominant form is a single parathyroid gland adenoma. We present a case of a 53-year-old patient, who was referred with primary hyperparathyroidism.
Leszek Sulkowski, Maciej Matyja
doaj +1 more source