Results 241 to 250 of about 62,914 (281)
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Journal of Clinical Endocrinology and Metabolism, 2018
Primary hyperparathyroidism (PHPT), the most common cause of hypercalcemia, is most often identified in postmenopausal women with hypercalcemia and parathyroid hormone (PTH) levels that are either frankly elevated or inappropriately normal. The clinical presentation of PHPT includes three phenotypes: target organ involvement of the renal and skeletal ...
John P Bilezikian
exaly +13 more sources
Primary hyperparathyroidism (PHPT), the most common cause of hypercalcemia, is most often identified in postmenopausal women with hypercalcemia and parathyroid hormone (PTH) levels that are either frankly elevated or inappropriately normal. The clinical presentation of PHPT includes three phenotypes: target organ involvement of the renal and skeletal ...
John P Bilezikian
exaly +13 more sources
Primary hyperparathyroidism [PDF]
Nature Reviews Endocrinology, 2017 In this Review, we describe the pathogenesis, diagnosis and management of primary hyperparathyroidism (PHPT), with a focus on recent advances in the field. PHPT is a common endocrine disorder that is characterized by hypercalcaemia and elevated or inappropriately normal serum levels of parathyroid hormone.
Marcella D Walker
exaly +3 more sources
Orthopaedic Nursing, 1994
Primary hyperparathyroidism is the most common cause of hypercalcemia seen in the outpatient setting (Bilezikian, 1992). Skeletal involvement is evident in most patients, even in the vast majority who show no symptoms. Bone histomorphometric studies reveal that the greatest bone diminution occurs in the radial shaft, the femoral neck is intermediate ...
M, Horowitz +4 more
openaire +4 more sources
Primary hyperparathyroidism is the most common cause of hypercalcemia seen in the outpatient setting (Bilezikian, 1992). Skeletal involvement is evident in most patients, even in the vast majority who show no symptoms. Bone histomorphometric studies reveal that the greatest bone diminution occurs in the radial shaft, the femoral neck is intermediate ...
M, Horowitz +4 more
openaire +4 more sources
Australian and New Zealand Journal of Surgery, 1971
The cases of 60 patients who underwent parathyroidectomy are described. Past, present and future aspects of the diagnosis of hyperparathyroidism, are discussed. In several patients in the series renal calculi had been present for over 20 years before the diagnosis was made. The reasons for this delay are considered.
R A, Evans, R E, Benson, N, Wyndham
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The cases of 60 patients who underwent parathyroidectomy are described. Past, present and future aspects of the diagnosis of hyperparathyroidism, are discussed. In several patients in the series renal calculi had been present for over 20 years before the diagnosis was made. The reasons for this delay are considered.
R A, Evans, R E, Benson, N, Wyndham
openaire +2 more sources
2006
Abstract Primary hyperparathyroidism is no longer the severe disorder of ‘stones, bones, and groans’ described by Fuller Albright and others in the 1930s (1,2). Osteitis fibrosa cystica, with its brown tumours of the long bones, subperiosteal bone resorption, distal tapering of the clavicles and phalanges, and ‘salt-and-pepper ...
Shonni J. Silverberg, John P. Bilezikian
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Abstract Primary hyperparathyroidism is no longer the severe disorder of ‘stones, bones, and groans’ described by Fuller Albright and others in the 1930s (1,2). Osteitis fibrosa cystica, with its brown tumours of the long bones, subperiosteal bone resorption, distal tapering of the clavicles and phalanges, and ‘salt-and-pepper ...
Shonni J. Silverberg, John P. Bilezikian
openaire +2 more sources
Primary hyperparathyroidism: Hyperparathyroid crisis
The American Journal of Surgery, 1981Hyperparathyroid crisis is a rare disease but should be suspected in acutely ill patients complaining of weakness, lethargy, nausea, vomiting, confusion and abdominal pain. Despite the variety of clinical manifestations, the syndrome forms a distinctive pattern which, in the presence of a serum calcium level greater than 16 mg/100 ml, should be ...
Joseph Zarconi, Thomas R. Kelly
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Current Treatment Options in Oncology, 2001
Treatment of primary hyperparathyroidism depends on a clear diagnosis based on biochemical confirmation. Most patients have an elevated serum total or ionized calcium level in association with an elevated or inappropriate serum intact parathyroid hormone level. The serum calcium level can be lowered by hydration and by a variety of pharmacologic agents.
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Treatment of primary hyperparathyroidism depends on a clear diagnosis based on biochemical confirmation. Most patients have an elevated serum total or ionized calcium level in association with an elevated or inappropriate serum intact parathyroid hormone level. The serum calcium level can be lowered by hydration and by a variety of pharmacologic agents.
openaire +3 more sources
Current Opinion in Oncology, 2004
This contribution presents research progress concerning primary hyperparathyroidism (pHPT), and the background for recent notable changes in treatment policy.Research has clarified that most patients with pHPT require surgery due to risk for osteoporosis, renal stones, and possibly silent complications of renal impairment, cardiovascular disease, and ...
Göran, Akerström, Per, Hellman
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This contribution presents research progress concerning primary hyperparathyroidism (pHPT), and the background for recent notable changes in treatment policy.Research has clarified that most patients with pHPT require surgery due to risk for osteoporosis, renal stones, and possibly silent complications of renal impairment, cardiovascular disease, and ...
Göran, Akerström, Per, Hellman
openaire +2 more sources
Current Opinion in Oncology, 2008
This article reviews the diagnosis and treatment of primary hyperparathyroidism, including recent literature on the subject.Important recent advancements in the field of parathyroid disease include improvements in preoperative localization, the use of intraoperative parathyroid hormone monitoring, and the development of minimally invasive and ...
Steven E, Rodgers +2 more
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This article reviews the diagnosis and treatment of primary hyperparathyroidism, including recent literature on the subject.Important recent advancements in the field of parathyroid disease include improvements in preoperative localization, the use of intraoperative parathyroid hormone monitoring, and the development of minimally invasive and ...
Steven E, Rodgers +2 more
openaire +2 more sources
Otolaryngologic Clinics of North America, 2010
Primary hyperparathyroidism is the most common cause of hypercalcemia in the outpatient setting. Phenotypically, it has evolved from a disease of overt symptomatology to one of vague complaints and biochemical diagnosis. Preoperative localization and intraoperative parathyroid hormone have revolutionized the surgical management of these patients ...
Erin A, Felger, Emad, Kandil
openaire +2 more sources
Primary hyperparathyroidism is the most common cause of hypercalcemia in the outpatient setting. Phenotypically, it has evolved from a disease of overt symptomatology to one of vague complaints and biochemical diagnosis. Preoperative localization and intraoperative parathyroid hormone have revolutionized the surgical management of these patients ...
Erin A, Felger, Emad, Kandil
openaire +2 more sources