Results 51 to 60 of about 5,676,941 (223)

Lipid‐based Nano‐delivery systems as a promising strategy for the treatment of epilepsy: Current status and challenges

Epilepsia Open, EarlyView.
Abstract Objective Epilepsy is a prevalent chronic neurological disorder characterized by abnormal neuronal electrical activity. The primary treatment modality for individuals with epilepsy (PWE) is antiseizure medication (ASM). The multiple potential factors contributing to treatment resistance in epilepsy may be attributed to the inability of ASMs to
Priya Kannan Varshini, Arunachalam Divya, Kumar Sowndharya, Parthiban Jeevitha, Selvam Manoj, Ashiq Rahman, Athil Ahamed, Ravichandiran Abirahul, Paranthaman Subash, Sulekha Khute   +9 more
wiley   +1 more source

Anatomical Understanding and Evolution of Surgical Treatment for Cancer of the Esophagogastric Junction: From Anatomical Controversies to Precision Surgery

Gut Medicine, EarlyView.
ABSTRACT The incidence of cancer of the esophagogastric junction (EGJC) has surged globally. Historically, its unique anatomical position and dual histological characteristics generated significant controversy regarding tumor classification and surgical strategies.
Cien Sun, Hao Liu, Dehua Ma, William C. Cho, Pasan Witharana, Jianfei Shen   +5 more
wiley   +1 more source

Establishment of Salivary Gland Tumors Arising in Salivary Gland‐Specific EWSR1::ATF1 Transgenic Mice

Head &Neck, EarlyView.
ABSTRACT Background Salivary gland carcinomas are uncommon malignancies with various histological subtypes harboring fusion genes. The EWSR1::ATF1 fusion gene, resulting from a translocation between chromosomes 12 and 22, is frequently observed in hyalinizing clear cell carcinoma (HCCC). However, the role of this fusion gene in HCCC oncogenesis remains
Yuri Hirai, Yoshitaka Utsumi, Daisuke Sano, Tatsu Kuwahara, Yoshihiro Aizawa, Takashi Hatano, Hisashi Hasumi, Yutaro Soejima, Tatsukata Kawagoe, Ryosuke Jikuya, Nobuhisa Mizuki, Satoshi Fujii, Toshitaka Nagao, Nobuhiko Oridate   +13 more
wiley   +1 more source

What Are We Learning About the Research‐Practice Gap From HRD Scholars and HRD Scholar‐Practitioners?

Human Resource Development Quarterly, EarlyView.
ABSTRACT The research‐practice gap (the gap) in HRD remains a significant challenge, hindering the application of academic research to practice and the integration of workplace challenges into research efforts. It is critical for HRD research to address the gap to develop evidence‐based solutions for learning and organizational performance. The purpose
Kelly Moore, Yonjoo Cho
wiley   +1 more source

Updated ERNICA guidelines for the management of rectosigmoid Hirschsprung's disease 2025

Journal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Objectives To revise the 2018 European Reference Network for rare Inherited and Congenital Digestive and Gastrointestinal Anomalies (ERNICA) clinical guideline for the management of rectosigmoid Hirschsprung's disease (HSCR) based on new evidence and evolving clinical priorities, ensuring continued relevance, trustworthiness, and consistency ...
Daniel Rossi, Willemijn Irvine, Anna Löf Granström, Annika Mutanen, Roel Bakx, Kristin Bjørnland, Duccio Cavalieri, Piotr Czauderna, Anne Dariel, Mark Ellebæk, Francesco Fascetti Leon, Fabio Fusaro, Dirk‐Jan Gloudemans, Marietta Jank, Peter Kolja Kvist, Martin Lacher, Annette Lemli, Lucas Matthyssens, Louise Montalva, Pedro Palazon, Alessio Pini Prato, Lucie Pos, Roxana Rassouli‐Kirchmeier, Konrad Reinshagen, Nagoud Schukfeh, Rony Sfeir, Olivia Spivack, Pernilla Stenström, Lovisa Telborn, Eelke Toxopeus, Alejandra Vilanova, Miriam Wilms, Rene Wijnen, Cornelius E. J. Sloots, Mikko Pakarinen, Tomas Wester   +35 more
wiley   +1 more source

Sono‐Anatomy and Histology of the Deep Fasciae in the Upper Limb

Journal of Ultrasound in Medicine, EarlyView.
The deep fascia of the upper limb represents a pivotal anatomical structure essential for effective force transmission, dynamic compartmentalization and musculoskeletal stability. Its composition (rich in type I collagen fibers) enables both mechanical resilience and functional adaptability, crucial for the upper limb's complex movements.
Carmelo Pirri, Nina Pirri, Lucia Petrelli, Veronica Macchi, Andrea Porzionato, Raffaele De Caro, Carla Stecco, Levent Özçakar   +7 more
wiley   +1 more source

Navicular and fifth metatarsal base stress fractures: An illustrated anatomical review

Knee Surgery, Sports Traumatology, Arthroscopy, EarlyView.
Abstract The navicular bone and the proximal fifth metatarsal (M5) play a vital role in maintaining the structural integrity and biomechanical stability of the foot's medial and lateral columns, respectively. Both bones' unique anatomical configuration, intricate mechanical environment and limited vascular supply make specific locations particularly ...
Xiuqi Liu, Choon Chiet Hong, Francisco Reina, Anna Carrera, Enric Alcolea‐Madera, Jorge Javier Del Vecchio, Miki Dalmau‐Pastor   +6 more
wiley   +1 more source

Sentipensar [Feel‐Thinking] Cultivates Collective Scientific Sensemaking and Worldbuilding Within and Beyond Ecological Despair

Science Education, EarlyView.
ABSTRACT Educating youth about environmental and climate justice is crucial in realizing a sustainable and flourishing future. Yet this can be challenging given the intense eco‐emotions youth experience and express while learning about these consequential realities and their implications.
Kelsie Fowler
wiley   +1 more source

Sustainable Healthy Diet Transitions: An Examination of Media Discourse Concerning Beef in the United Kingdom From 2018 to 2022

Sustainable Development, EarlyView.
ABSTRACT The role of diet in individual and planetary health is increasingly scrutinised as consumers are encouraged to make food choices that balance health and sustainability, particularly with beef. While prior research has considered reduction from the perspective of alternate product acceptance, the social context of beef is less understood. Media
Sean Tanner, Mary McCarthy, David Giles
wiley   +1 more source

Mammalian Osteoderm Ultrastructure in the Armored Acomys Spiny Mouse Tail

Small, EarlyView.
The ultrastructure of armored platelets – termed osteoderms – in the tail skin of Acomys cahirinus spiny mice is characterized using 2D and 3D microscopy methods. The imbricated structure is composed of calcium phosphate biomineral and has select structural elements that are bone‐like and tooth‐like in nature.
Joseph Deering, Malcolm Maden, Marc D. McKee   +2 more
wiley   +1 more source