Results 111 to 120 of about 214,996 (309)

Sertraline Treatment Can Mimic Niemann‐Pick Type C Biomarker Profile: A Diagnostic Pitfall

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Oxysterols (cholestane‐3β,5α,6β‐triol and 7‐ketocholesterol) and N‐palmitoyl‐O‐phosphocholineserine (PPCS) are sensitive biomarkers for Niemann‐Pick disease type C (NPC) screening. However, false‐positive results occur, with a biomarker profile suggestive of NPC despite the absence of pathogenic variants in genes involved in NPC or ...
Maria Makrygianni, Cecile Pagan, Antony Citterio‐Quentin, Isabelle Rouvet, Giulia Dingeo, Cyril Hanin, Claudine Laurent‐Levinson, Samia Pichard, Bénédicte Héron, Clément Gourguechon, Daniele Mandia, Jerome Guitton, Carole Lacout, Nicolas Schleinitz, Florient Potier, Olivier Flabeau, Elsa Besse‐Pinot, Foudil Lamari, Magali Pettazzoni, Yann Nadjar   +19 more
wiley   +1 more source

Neck atonia with a focal stimulation-induced seizure arising from the SMA: pathophysiological considerations.

, 2012
A 28-year-old patient with pharmacoresistant non-lesional right frontal epilepsy underwent extra-operative intracranial EEG recordings and electrical cortical stimulation (ECS) to map eloquent cortex.
Nachev, P, McEvoy, Andrew W., Wehner, T, Kovac, S, Diehl, B, Duncan, JS, Duncan, John S., Rodionov, Roman, Toms, Nathan, Toms, N, Diehl, Beate, Kovac, Stjepana, Wehner, Tim, Scott, Catherine, Nachev, Parashkev, Scott, C, Rodionov, R, McEvoy, AW   +17 more
core   +1 more source

Anti‐CD19 CAR T Cells in Autoimmune Encephalitis: Inflammation Controlled, Neurodegeneration Unchecked?

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Just recently, successful chimeric antigen receptor (CAR) T cell therapy was reported in the first patient with refractory, anti‐diacylglycerol lipase alpha (DAGLA) antibody‐mediated autoimmune encephalitis, achieving partial clinical remission.
Dimitrios Mougiakakos, Marwa Al‐Dubai, Denise Walther, Dominic Borie, Jan D. Lünemann, Marc Pawlitzki, Sven G. Meuth, Solveig Henneicke, Stefan Vielhaber, Stefanie Schreiber   +9 more
wiley   +1 more source

Exploring the Functional Brain Activity of Motor Control of Abdominal Muscle Associated with Voluntary Voiding Based on Functional Near-Infrared Spectroscopy

康复学报
ObjectiveThe contractions of abdominal muscle during voluntary urination is a motor control task, Which aims to explore the central activity characteristics of this action with functional near-infrared spectroscopy (fNIRS).MethodsA total of 19 healthy ...
SHI Yinshuang, WANG Menghuan, PAN Yingying, LIN Feng   +3 more
doaj  

Brain Activation During Motor Preparation and Execution in Patients with Mild Cognitive Impairment: An fNIRS Study

Brain Sciences
Objectives: This study aimed to investigate how motor preparation impacted brain activation in individuals with differing cognitive statuses. Methods: We investigated the cortical activation pattern of 57 individuals with mild cognitive impairment (MCI ...
Hanfei Li, Chenyu Fan, Ke Chen, Hongyu Xie, Guohui Yang, Haozheng Li, Xiangtong Ji, Yi Wu, Meng Li   +8 more
doaj   +1 more source

Association Between Motor Pathway Damage and Motor Deficit in Upper and Lower Limb in People With MS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Corticospinal tract damage is common in people with MS, but the degree of clinical symptoms varies. We hypothesize that corticospinal tract lesions are more extensive and severe in people with MS with motor impairments in both upper and lower limbs.
Mathilde Liffran, Malo Gaubert, Alice Dufey, Elise Bannier, Audrey Rico, Jean‐Christophe Ferré, Raphaël Chouteau, Laure Michel, Emmanuelle Le Page, Virginie Callot, Bertrand Audoin, Sarah Demortière, Benoît Combès, Anne Kerbrat   +13 more
wiley   +1 more source

The role of primary motor cortex : more than movement execution

, 2020
The predominant role of the primary motor cortex (M1) in motor execution is well acknowledged. However, additional roles of M1 are getting evident in humans owing to advances in noninvasive brain stimulation (NIBS) techniques.
Abualait, Turki, Yoo, Woo-Kyoung, Chen, Annabel Shen-Hsing, Shahid Bashir, Kashyap, Rajan, Bashir, Shahid, Bhattacharjee, Sagarika   +6 more
core   +1 more source

Cognitive Neural Prosthetics: Brain Machine Interfaces Based in Parietal Cortex [PDF]

, 2005
Systems neuroscience has recently emerged as an applied field in the form of neural prosthetic development. This integration of empirical systems neuroscience with engineering in order to develop functional interfaces between external devices and the ...
Meeker, Daniella Elena Patricia
core   +1 more source

Effect of functional electrical stimulation hand cycling on functional connection of brain networks in stroke patients: a study based on functional near-infrared spectroscopy

Zhongguo kangfu lilun yu shijian
Objective To explore the potential central mechanisms of functional electrical stimulation (FES) hand cycling in promoting upper limb motor recovery after stroke.
XU Sheng, ZHANG Min, YANG Qingqing, WANG Qinglei, GENG Ayan, WANG Tong, GUO Chuan   +6 more
doaj   +1 more source

Spatial and Volumetric Characteristics of Glioblastoma: Associations With Clinical Presentation and Survival

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective We aim to comprehensively analyze how regional tumor and edema characteristics are associated with clinical presentations and survival outcomes in a large cohort of glioblastoma patients. Methods Patients with IDH‐wildtype glioblastoma who received brain MRI from 2010 to 2023 were included.
Daniel J. Zhou, Marc Jaskir, Julian Gal, Yombe Fonkeu, Christos Davatzikos, MacLean P. Nasrallah, Jose Garcia, Rubo Xing, Stephen J. Bagley, Arati Desai, Richard E. Phillips, Steven Tobochnik, Colin A. Ellis, James J. Gugger, Nishant Sinha, Joel M. Stein, Kathryn A. Davis   +16 more
wiley   +1 more source